滥用药物体内代谢的研究进展

毒品在体内尿苷二磷酸葡醛酸转移酶、细胞色素P450、羧酸酯酶、磺基转移酶、丁酰胆碱酯酶、儿茶酚-O-甲基转移酶和吗啡6-脱氢酶等代谢酶催化下,发生葡萄糖醛酸化、水解、氧化、磺酸化等多种反应,生成有活性或者无活性的代谢产物,然后经尿液、胆汁或者其他途径排出体外。不同毒品的代谢途径不同。本文介绍了近年来吗啡类、苯丙胺类、氯胺酮、大麻类和可卡因等毒品在人和动物体内的代谢研究,综述了这些毒品体内代谢的代谢部位、代谢酶、代谢产物及其生理活性的研究进展。     

Who speaks for the European border security industry? A network analysis

This article contributes to the literature on the European border security industry with a network analysis of a new bipartite data set. The network is composed of speakers and their speech topics at a European border security conference taking place from 2008 to 2015. Speakers are linked to conferences by year of attendance and to speech topics to identify key actors and discourses using measures of centrality. A multiple regression quadratic assignment procedure (MR-QAP) is used to explain the continuity of conference speech topics. The centrality analysis reveals a number of “hubs” and the discourse analysis reveals a consistent focus on social control and surveillance over human rights. The MR-QAP regression suggests that shared discourses are driven by organisations which act as key speakers at many events, and whose discourses are prioritised over those of other actors. The article concludes with notes on the critical implications of the findings.     

四妙除痹汤内服外洗治疗热痹60例

目的：观察四妙除痹汤内服外洗对热痹（风湿类疾病急性期或活动期）患治疗前后体温（T）、血沉（ESR）、C反应蛋白（CRP）、抗“O”（ASO)变化及临床疗效。方法：96例热痹患，随机分为治疗组（60例）和对照组（36例），分别给予四妙除痹汤及布洛芬片治疗，观察其疗效及治疗前后T、ESR、CRP、ASO变化。结果：四妙除痹汤治疗热痹汤治疗热痹具有明显的疗效（P＜0．01），并与其降低T、ESR、CRP、ASO 等相关（P＜0．01）。结论：四妙除痹汤对热痹患有一定疗效。     

网络媒体的发展对期刊媒体的影响与对策

互联网在中国的迅猛发展 ,给传统媒体带来了深刻的影响和冲击。网络扩大了信息传播 ,实现了受众体的自由选择。要充分利用网络信息传递快速及时的特点 ,为期刊选题策划提供信息服务。在信息传播现代化的社会 ,期刊应加快适应社会的步伐 ,不断完善其功能 ,发挥自身的优势 ,以适应市场经济的需要。     

正确认识网络对青少年的影响

网络对青少年的正面影响是 :有助于青少年掌握现代科学文化知识 ;有助于培养和树立青少年的现代观念 ;有助于青少年建立新型的社会关系。负面影响是 :可能使青少年对现实认识发生扭曲 ,由于网络中灰色化信息泛滥 ,使得青少年的人生观、价值观受到冲击 ,因此 ,我们必须加强网络文明建设。     

猪圆环病毒2型感染对猪肺泡巨噬细胞生物学活性的影响

将猪圆环病毒2型(PCV2)BF株经口、鼻接种40日龄健康仔猪,在接种后不同时间宰杀,收集猪肺泡巨噬细胞(PAM),同时设立对照。用FITC-Annexin V/PI双染色流式细胞术和琼脂糖凝胶电泳检测PAM凋亡现象,通过EA花环试验测定Fc受体数目,通过吞噬鸡红细胞试验测定吞噬功能,分析PCV2感染对PAM生物学活性的影响。结果显示,在整个试验期内2种方法均没有检测到PAM凋亡,表明PCV2感染不会诱发PAM凋亡。PAM的Fc受体数和吞噬鸡红细胞数的变化规律一致,与对照组相比,两者数量在接种后第3 d明显下降,第7 d有所回升,之后基本恢复,表明PCV2感染后PAM吞噬和清除病原的功能出现短暂下降。     

法律行为形式要件的类型分析

法律行为的形式要件能够影响到法律行为的效力,是法律行为效力的重要因素。笔者针对学界对形式要件类型的不同说法,以历史的视角去分析如何确立法律行为形式要件类型的应然形态,并基于现代民法强调方式自由之宗旨认为:对于法律行为以不要式为原则,以要式为例外;只要当事人的表意行为符合法律行为的其他成立要件,并且其意思表示足以为外界所客观识别,原则上可采取其意欲的任何形式,法律上不加干涉。从而在此基础上确立法律行为形式要件基本类型。     

高等院校网上信息安全的防范

全国高等院校办公及文档上网工程中潜在的不安全因素,应采取措施解决网上安全问题。     

用间接免疫酶组化法检测“502”胶显现人指纹ABO血型的研究

本文研究应用间接免疫酶组化法检测“502”胶显现人指纹的ABO血型.结果显示69例个体中,检出65例指纹的ABO血型,检出率为94.2%.该方法具有特异性好、准确灵敏、结果可靠、重复性好等特点,为法医物证检验个人识别提供了一种新的手段.     

Understanding the Structure of a Large Heroin Distribution Network: A Quantitative Analysis of Qualitative Data

An analysis is reported of 2,408 wiretap conversations gathered in the course of prosecuting a heroin dealing organization in New York City in the 1990s. The five-step analysis, which included a social network analysis of phone contacts, revealed a large, loosely structured group of 294 individuals, most of whom had very limited contacts with others in the group. The group’s active core comprised 38 individuals with extended contacts, little status differentiation and some task specialization. A smaller more tightly connected group of 22 individuals was somewhat independent of the remainder of the core and appeared to constitute a “communal business”. The existence was not confirmed of the large criminal conspiracy described by the prosecution that operated at all levels of trafficking and dealing, from wholesale distribution to street sales. Rather, it appeared that the 294 individuals comprised one segment of the heroin market in the city. However, the discrepancy could be due to the fact that the prosecution drew upon a wider set of information about the individuals concerned than provided by the wiretap data. The study supports recent analyses that see organized crimes, such as drug trafficking, as mostly the work of small groups of loosely linked entrepreneurs rather than large, highly structured criminal syndicates.