益气养阴活血通腑法为主治疗老年早期糖尿病肾病31例

目的 :观察益气养阴活血通腑法为主对老年早期糖尿病肾病 (DN)的临床疗效。方法 :随机将 50例老年早期DN患者分为西药对照组 (简称对照组 ) 19例和中西药并用治疗组 (简称治疗组 ) 31例。对照组予常规降血糖、糖尿病教育及对症处理 ,治疗组加用以益气养阴活血通腑为主的中药治疗。结果 :在治疗 8周后 ,治疗组 2 4h尿清蛋白排泄量 (UAE)显著减少 (P <0 .0 1) ,与对照组比较有显著性差异 (P <0 .0 1)。结论 :益气养阴活血通腑法为主对老年早期DN具有较好的肾脏保护作用。     

做实高速公路交通安全管理工作的五点思考

高速公路具有车流量大、行车速度快等特点。一旦发生交通事故，多为车毁人亡，甚至造成多车连环追尾、死伤惨重的重特大恶性交通事故。基层高速交警除了在日常勤务中履行交通法规宣传职责，加大对交通参与者进行交通安全宣传和“五进”宣传力度外，应从贴近路面、贴近群众、贴近业主单位出发，在实际工作中寻找预防交通事故的切入点，强化交通安全管理，确保高速公路平安、畅通。     

论国际海运货物保险的保险利益

本文分析了英国法环境下国际海运货物保险利益界定的弊端 ,建议我国确立以“风险承担”为界来界定保险利益的法律模式 ;结合实际对实务中颇具争论的“保险利益的相对性”、“保险利益与保险合同效力”和“保险利益与损失”等问题进行了研究 ,提出了自己的观点和立法建议。     

试析物资采购中的贪污手段及查验对策

贪污犯罪常见于物资采购业务中 ,作案人常用的手段有变换单据金额、重复报帐、编造业务等。通过对原始凭证的查验 ,能够收集贪污犯罪的会计证据 ,从而揭露和证实犯罪。实践中需要查验的主要内容有单据的规格、质量 ,单据上字迹书写程度及特征 ,涂改的字迹 ,发票开具者与收款者、单据的印鉴与单据是否相符 ,单据的遮盖点 ,发票的填制时间及号码等等。     

Replevin – Repeal or Retain?

In the light of the current Green Paperproposing extensive reform of bailiff'slaw in England and Wales, this article weighsup the arguments for and against retaining themedieval remedy of replevin (a processfor the summary recovery of goods seized indistraint and the subsequent trial of thelegality of their seizure). The common law andstatutory provisions are reviewed and compared.It is concluded that there is no need to retainreplevin, as the statutory procedure availablein cases of wrongful interference withgoods provide equivalent remedies, without anyof the procedural and costs disadvantages ofreplevin.     

Differentiation of vaginal cells from epidermal cells using morphological and autofluorescence properties: Implications for sexual assault casework involving digital penetration

This work explores morphological and autofluorescence differences between vaginal and epidermal cells detectable through Imaging Flow Cytometry (IFC), a non-destructive, high-throughput technique. These differences were used to build a predictive framework for classifying unknown cells as originating from vaginal or epidermal tissue, which was tested on hand swabbings with and without digital penetration. Many more cells possessing a vaginal signature (median posterior probability ≥0.90) were detected in digital penetration samples than control hand swabbings. Minimum interpretation thresholds were developed to minimize/eliminate false positives; these thresholds were also effective when screening licked hands, indicating the potential utility of this method for a variety of biological mixture types and depositional events relevant to forensic casework.     

Novel cellular signatures for determining time since deposition for trace DNA evidence

With the increase in sensitivity of DNA profiling, questions about how and when the DNA was deposited have become a driving issue in forensic cases. To address this, we propose a novel method to determine time since deposition of trace DNA samples based on morphological and autofluorescence properties of individual epithelial cells which can change as the sample ages. To develop this signature, a series of trace DNA samples were generated by contact/handling a substrate and then allowed to age anywhere between one day and more than one year prior to collection. Imaging flow cytometry (IFC) was then used to characterize the morphology and autofluorescence profiles of individual cells within each sample followed by multivariate modelling and predictive classification.Resultsshowed that epithelial cell populations could be classified with high accuracy (∼90%) into one of three time-since-deposition groups: < 1 week, between 1 week and 2 months, and > 2months. Differences across age groups were largely driven by decreases in brightfield contrast and increases in the intensity of autofluorescence. To further test this approach for forensic casework, 47 individual donor cell populations spanning each time deposition group were classified blindly against the remaining data set. Samples containing at least 75 cells and a posterior probability greater than 0.90 showed classification accuracies ∼95%. Accuracies for individual time groups were 97% (<1 week), 92% (1week-2months), 98% (>2 months) with an average posterior probability for all time groups ∼0.96. This indicates that autofluorescence and morphological analyses may provide probative information regarding time since deposition for many types of trace DNA samples in forensic casework.     

刍论细节管理的现实选择

增强责任心是做好细节管理的基础,提高复制能力是做好细节管理的必需,养成高度的职业能力是做好细节管理的根本,建立数字化指标是做好细节管理的手段,遵循完善的流程是做好细节管理的精髓,培养规则意识是做好细节管理的保障,关键的、有效的细节决定成败。总体而言,规则意识、数字化管理、职业能力、完善的流程和抓好有效细节等是实现细节管理的关键和保证。     

DVC微量注射VIP对大鼠GMBF放大和电针调整效应

目的：采用中枢迷走神经背核复合体（DVC）微量注射血管活性肠肽（VIP），观察胃黏膜血流量（GMBF）变化和电针对GMBF的调整作用。方法：采用脑立体定位仪对大鼠中枢进行定位和注射，电针足三里穴，用氢气清除法测定GMBF；放射免疫法测量外周血中VIP含量。结果：DVC微量注射VIP后，血中VIP含量增加（P＜0．01），GMBF明显增加（P＜0．01）。电针（EA）足三里穴加强了GMBF放大效应。结论：DVC注射VIP对GMBF有放大效应，证实在神经－内分泌－免疫网络系统（NEIS）中VIP是重要的神经肽，DVC是VIP作用的社会中枢特异性部位之一，电针具有协同作用。