城市轨道交通对旅游边缘区旅游增长极影响机制研究——以杭州为例

论文首先从城市轨道交通建设改善城市旅游边缘区可达性、城市轨道交通建设促进对城市旅游边缘区的旅游需求、城市轨道交通建设促进对城市旅游边缘区的旅游需求、城市轨道交通建设促进新城区的建设等4方面分析了城市轨道交通建设对城市旅游增长极形成与发展的影响机制,然后以杭州市为例,从杭州城市旅游边缘区人口的增长、杭州城市轨道建设与旅游边缘区旅游需要统筹发展、杭州城市轨道交通建设尽可能向城市旅游边缘区腹地拓展等3方面论述了杭州城市轨道交通建设对杭州城市旅游边缘区旅游增长极形成与发展的影响。     

群体性事件的成因与对策探析

市场经济的建设呼唤着民主进程的加速推进,它一方面唤醒了民众的主体维权意识,另一方面过渡膨胀的主体意识,又诱发了大量的群体性事件的发生。在转型期社会中,为了有效控制群体性交发事件发生：一要保持畅通的公力救济渠道;二要坚持社会公平的制度取向,防止贫富差别日益扩大;三要转变政府职能,规范政府行为,切实维护群众利益;四要建立起相应的利益表达机制。     

电感耦合等离子体质谱法测定金寨地区仿野生茯苓不同部位及其土壤中11种无机元素

目的 探究无机元素在金寨地区仿野生茯苓不同用药部位中的分布及在土壤中的富集特点。方法 采用微波消解法处理茯苓皮、白茯苓、赤茯苓及其菌核生长附近土壤,应用电感耦合等离子体质谱法测定茯苓不同部位及其土壤中K、Na、Mg、Fe、Mn、Zn、Cu、Se等11种无机元素含量。结果 金寨地区仿野生茯苓各部位元素分布有一定差异,大多数元素在茯苓皮中含量较高,茯苓不同部位总的无机元素含量从高至低顺序为茯苓皮、赤茯苓、白茯苓;茯苓不同部位对无机元素的吸收有选择性,但均以K、Fe、Mg、Na含量较高;茯苓不同部位对11种元素的富集系数存在差异,变化范围为0.005 2～0.782 3。结论 所建立的电感耦合等离子体质谱法简便、准确,适用于金寨地区仿野生茯苓不同部位及土壤中11种无机元素的含量测定。     

Potential for the Remediation of Methamphetamine Contamination Using Ozone,

The deposition of methamphetamine within indoor environments due to illegal activities can pose a health risk for occupants. Current cleaning techniques are costly and inefficient, calling for the development of alternative remediation methods. In addition, the fate of methamphetamine in indoor environments is largely unknown, negatively impacting our knowledge on the health risks associated with contaminated dwellings. Under the conditions of this study, 97% of surface deposited methamphetamine on a paper substrate was consumed after 12 min of exposure to ozone, thus demonstrating potential for its use as a remediation agent. The reaction had an effective second‐order rate constant with an upper limit of 2.15 ± 1 × 10^?18 cm³/molecule/s, and the main product observed was phenyl‐2‐propanone (P2P) at 8.3% yield, as determined using GC/MS. Several products observed in this study have also been reported as by‐products of methamphetamine synthesis, including P2P—a known methamphetamine precursor, which indicates that their detection at a potential clandestine site is not necessarily evidence of manufacture.     

Carbon‐Based Fingerprint Powder as a One‐Step Development and Matrix Application for High‐Resolution Mass Spectrometry Imaging of Latent Fingerprints

Carbon‐based materials are often used as matrices for matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS) and its imaging (MALDI‐MSI). However, researchers have refrained from using carbon‐based fingerprint powder (CFP) as a matrix due to high background and contamination. In this work, the compatibility of CFP is reevaluated with MALDI‐MSI using a high‐resolution mass spectrometer (HRMS) and compared to traditional organic matrices. Relevant fingerprint compounds were easily distinguished from carbon cluster peaks when using HRMS. For fair comparison, half of a fingerprint was dusted with CFP while the other half was dusted with traditional organic matrices. All compounds studied had comparable, or higher, signal‐to‐noise (S/N) ratios when CFP was used as the matrix. Additionally, chemical image qualities closely followed the trend of S/N ratios. CFP proved to be an effective one‐step development and matrix application technique for MALDI‐MSI of latent fingerprints, when carbon cluster peaks are well separated by a HRMS.     

Enantiomeric Identification of Pregabalin by GC‐MS via Methylation and S‐TPC Chiral Derivatization

Pregabalin is a Schedule V controlled substance which is defined as the (S) enantiomer of 3‐(aminomethyl)‐5‐methylhexanoic acid. It is used legitimately to treat neuropathy in patients with diabetes as well as for epilepsy and fibromyalgia. Pregabalin is an amino acid and an amphoteric compound, which makes it difficult to analyze using the conventional GC‐MS instrumentation found in most forensic drug analysis laboratories. Problems associated with the traditional GC‐MS analysis of pregabalin include selective solubility, ring closure to the corresponding lactam in the GC injection port and/or the MS transfer line and difficulty with chiral derivatization due to the presence of a carboxylic acid moiety. Here, we show that these challenges can be overcome by methylating (capping) the carboxylic acid portion of the pregabalin molecule and converting to the corresponding methyl ester. Once the methyl ester is synthesized, chiral derivatization at the amine can be achieved to identify the controlled (S) enantiomer of pregabalin via GC‐MS.     

Alprazolam and Zolpidem in Skeletal Tissue of Decomposed Body Confirms Exposure

In several medico‐legal cases, bone samples analysis may provide the only source of toxicological information. This case study reports the analysis of a human bone specimen, belonging to a 46‐year‐old man, found 3 months after his death due to cervical–thoracic injuries in a motorcycle accident. Bone specimen was the only available material for toxicological analysis, among few skull hair and rotten skin. Analysis was performed by a newly developed and validated ultra‐high‐pressure liquid chromatography–mass spectrometry/mass spectrometry (UHPLC‐MS/MS) method, following simple and efficient sample pretreatment. The results were in accordance with the man's medical record: Alprazolam and zolpidem were found at 2.2 and 5.4 ng/g of bone, respectively. Both these drugs were prescribed to the deceased.     

A Fatal Case of Poisoning with Fentanyl Transdermal Patches in Japan

Fentanyl transdermal patches have been used to treat cancer‐ and noncancer‐related chronic pain. However, its inappropriate or illegal application may cause fatal poisoning. We herein present the case of a Japanese woman in her 40s who was found dead with seven 25‐μg/h fentanyl transdermal patches on her body. We established a detailed toxicological analysis procedure to quantify fentanyl, and its metabolite norfentanyl, and other drugs (acetaminophen, allylisopropylacetylurea, celecoxib, estazolam, promethazine, and sertraline) in human whole blood by ultra‐high‐performance liquid chromatography–tandem mass spectrometry. The measured fentanyl and norfentanyl concentrations in the femoral and cardiac blood were 0.051 and 0.072 μg/mL and 0.033 and 0.076 μg/mL, respectively. The decedent's fentanyl concentrations were consistent with previously reported postmortem blood levels for fatal cases of poisoning by fentanyl transdermal patches. Based on the decedent's case history, autopsy findings, and toxicological analyses, the cause of death was identified as intoxication with transdermal fentanyl.     

Mass murders in Germany – classification of surviving offenders based on the examination of court files

Personality, psychopathology, and motives of 44 surviving offenders committing mass murder in Germany over 25 years (1984–2009) were analyzed using court files and psychiatric expertises. Initially, 123 mass murders in Germany were detected in the time period 1980–2010 (inclusive deceased offenders). Using a data entry form based on ViCLAS (Violent Crime Linkage Analysis System), we categorized the 44 surviving mass murderers into three prototypes using the ‘TwoStep Cluster’-method (separation of the offenders in different groups depending on their similarity of specific items): 1. Narcissistic or aggressive men suffering from addiction or affective disorder, committing mass murder out of rage/hate when being intoxicated by alcohol, 2. Psychotic offenders with schizophrenia and comorbid substance abuse. 3. Aggressive, narcissistic or anxious adolescents, half of them suffering from affective disorder or ADHD, committing mass murder out of rage/hate. Not included are such events where the offenders died and therefore no court files or psychiatric expertises were available. Classification and subtyping of the offenders’ personalities and psychopathological conditions might help to improve the chances for an early detection of persons at risk.     

Fear of terrorism: media exposure and subjective fear of attack

In many Western countries, citizen knowledge of terrorist events is intrinsically shaped by the style of broadcasted messages published by the media. Media discourses regarding terrorist acts raise questions about how such rhetoric elicits fear in people who typically experience such events through news reports. However, we do not fully understand the impact of the media on perceptions of terrorism as clearly as we understand the relationship between the media and fear of crime. This study examines how media sources accessed actively (e.g. through newspapers; Internet) or passively (e.g. through television; radio) influence knowledge and fear of terrorism. We find receiving information about terrorism from multiple media sources increases fear of terrorism, but media sources accessed passively are not as influential as media sources accessed more actively. These results highlight how media consumption from various sources may affect one’s fear of terrorism, and further illustrates how the role of perceived knowledge may exacerbate or mitigate fear. Implications for policy and practice are discussed.