我国媒介组织结构的设计及其发展趋势

科学地设计媒介组织结构对于保障我国媒介企业高效运作并实现其目标具有十分重要的意义。进行媒介组织结构的设计,必须考虑媒介所处环境、媒介的经营战略与目标、技术和规模等因素的影响,同时兼顾效益目标、分工协作、统一指挥、权责对等、合理管理幅度与层次以及集权与分权原则。随着时代的变化,媒介企业正在尝试用市场和非层级制组织形式代替层级制,扁平化、小型化、网络化、弹性化和团队化等趋势日益明显。     

加快推进结构调整 实现长春经济跨越式发展

长春市经济结构主要问题是产业结构低度化、调整机制尚未形成、城镇化水平低。只有加快结构调整,才能实现跨越式发展。调整必须确定新的思路,用高技术特别是信息技术改造和提升传统产业,创造新的优势：用信息化和城镇化推动农村结构调整,创造独特优势;调整所有制结构,创造体制优势。长春市经济结构调整和跨越式发展的有利条件包括调整和发展面临难得的历史机遇,调整和发展的空间广阔,物质技术基础雄厚等。     

Museums for peace: agents and instruments of peace education

Although museums for peace claim peace education to be a primary mission, their definitions of ‘peace’ and their aims and practices for peace education vary widely. In this article, we draw from the field of critical museology and the knowledge construction perspective to understand the role of museums for peace in the service of peace education. From the constructivist viewpoint, the museums’ narratives are not objective or historical truths. Rather they are the museum designers’ constructed interpretations of the events, people, and places that are memorialized. The museums’ exhibits, narratives, and programs reflect a wide range of definitions of peace including some which conflict and contradict each other. The variations in defining peace contribute to differences in how the museums view and exercise their role in educating for peace. From this analysis, we observe how contemporary museums for peace can play a significant role in peace education by raising awareness about multiple definitions of peace and by enabling audiences to reflect on, discuss and participate in deliberated paths toward personal peace and cultures of peace.     

六味地黄汤通过树突状细胞Notch信号通路调节T细胞分化干预自身免疫性脑脊髓炎

目的 通过观察树突状细胞(dendritic cells,DCs)Notch信号通路对CD4+T细胞分化的影响,探究六味地黄汤干预实验性自身免疫性脑脊髓炎(experimental autoimmune encephalomyeli-tis,EAE)的机制.方法 采用主动免疫法诱导2D2小鼠EAE模型,采用磁珠分选收集...     

加快完善社会主义市场经济体制的理论认知与现实路径

我国经济体制由计划经济向市场经济转变是历史的选择。社会主义市场经济具有坚持公有制为主体、多种所有制经济共同发展和按劳分配为主体、多种分配方式并存,把社会主义制度和市场经济有机结合起来,不断解放和发展社会生产力的显著优势,是中国共产党和中国人民的伟大创造。新时期,应紧紧围绕"政府和市场"关系这一核心问题,按照"市场机制有效、微观主体有活力、宏观调控有度"的要求,多措并举,加快完善社会主义市场经济体制。     

OFDI如何影响装备制造企业结构性分解的全要素生产率？——基于差异性路径的分析

将全要素生产率结构性分解为三个维度，即技术进步、纯技术效率以及规模效率，这三种形式也可看作是OFDI影响企业全要素生产率提升的差异性路径，基于这三类差异性路径，构建了中国装备制造业OFDI与全要素生产率之间的机制分析框架。借助中国装备制造业上市公司数据，利用倾向得分匹配（PSM）方法从实证角度验证OFDI提升装备制造企业全要素生产率的差异性路径，并检验了OFDI分别对装备制造业下六个细分行业中微观企业全要素生产率的影响效应。结果显示，装备制造业上市公司OFDI显著促进纯技术效率提升，但显著抑制规模效率。且正负向效应都逐年减弱。分样本数据显示，交通运输设备以及计算机通信和其他电子设备制造企业OFDI对纯技术效率和规模效率的影响效应最为显著。     

社会整合:新时代推进党建引领城市基层治理的有效路径

党建引领城市基层治理是党中央强化基层党建、推动基层治理的重大战略部署,亟待学术界予以研究和回应。城市基层党组织可以充分发挥社会整合功能,通过利益整合、结构整合和价值整合达成稳固党的基层政权、提升社区可治理性和强化社区凝聚力等目标,以此实现政党领导和治理绩效之间双向促进的良性循环。城市基层党组织应当以社会整合为着力点,从以推动利益协调和红色网格建设强化党组织权威、以形塑家庭关系和公益网络培育横向合作关系、以培育文化共同体和议题设置能力提升传播有效性等方面来构建党建引领基层治理的实践路径。     

双循环新发展格局的研究视角、逻辑主线和总体框架

加快构建双循环新发展格局是我国经济全球化战略转型的重大选择。内需主导型全球价值链可以作为我国构建新发展格局理论和实践研究的一种切入视角。构建双循环新发展格局是技术大变革之下全球价值链分工动态演变和深化的理论逻辑使然，也是改革开放以来经济发展规律自然演进的历史逻辑使然，更是进入新发展阶段的需求端、供给端和制度端发展条件变化的现实逻辑使然。构建双循环新发展格局的总体框架可以概括为：首先，基于内需市场构建国内价值链，形成国内大循环；其次，实现国内价值链与全球价值链深度对接，以国内大循环带动国际循环；最后，以国际循环促进国内循环，形成双循环相互促进的新发展格局。其中的政策实施重点在于，要坚持以推动高质量发展为主题，坚持以深化供给侧结构性改革为主线，坚持系统观念，统筹发展和安全，加快建设现代化经济体系。     

Identifying reliable ions for the statistical differentiation of structurally similar fentanyl analogs

Definitive identification of fentanyl analogs based on mass spectral comparison is challenging given the high degree of structural and, hence, spectral similarity. To address this, a statistical method was previously developed in which two electron-ionization (EI) mass spectra are compared using the unequal variance t-test. Normalized intensities of corresponding ions are compared, testing the null hypothesis (H₀) that the difference in intensity is equal to zero. If H₀ is accepted at all m/z values, the two spectra are statistically equivalent at the specified confidence level. If H₀ is not accepted at any m/z value, then there is a significant difference in intensity at that m/z value between the two spectra. In this work, the statistical comparison method is applied to distinguish EI spectra of valeryl fentanyl, isovaleryl fentanyl, and pivaloyl fentanyl. Spectra of the three analogs were collected over a 9-month period and at different concentrations. At the 99.9% confidence level, the spectra of corresponding isomers were statistically associated. Spectra of different isomers were statistically distinct, and ions responsible for discrimination were identified in each comparison. To account for inherent instrument variations, discriminating ions for each pairwise comparison were ranked based on the magnitude of the calculated t-statistic (t_calc) value. For a given comparison, ions with higher t_calc values are those with the greatest difference in intensity between the two spectra and, therefore, are considered more reliable for discrimination. Using these methods, objective discrimination among the spectra was achieved and ions considered most reliable for discrimination of these isomers were identified.     

Comparisons between Japanese and Han Chinese populations for 261 autosomal STR loci

In this study, Japanese and Han Chinese individuals (n = 32, each) were genotyped for 261 autosomal STRs, and allele frequencies were calculated for each locus in each population. The average number of alleles for all loci in Japanese and Han Chinese populations was 6.65 and 6.56, respectively. The tests for deviations from HWE performed using an exact test showed that the number of STRs (P > 0.05) in Japanese and Han Chinese populations was 236 and 241, respectively. Calculation of forensic parameters showed heterozygosity, and the exclusion means in the Japanese population were 0.7185 and 4813 and those in the Han Chinese population were 0.7308 and 0.5008. In addition, population genetic analyses, such as principal component analysis and factorial correspondence analysis, were performed and a differential formula with likelihood ratios was applied for various number of STR loci based on the effectiveness of differentiation between the two populations. Accordingly, this study suggests that statistical differentiation between genetically close populations, such as the Japanese and Han Chinese populations, is possible if approximately 40–50 effective STR loci are analyzed.