中西医结合除铜治疗对肝豆状核变性患者肝硬化的长期疗效观察

目的:观察长期中西医结合除铜治疗对肝豆状核变性(hepatolenticular degeneration,HLD)肝硬化的疗效.方法:对首次入院未经正规除铜治疗的48例HLD患者分别在中西医结合除铜治疗前、疗后1年和疗后2年行Child-Pugh分级评分,并行血清透明质酸(hexadecenoic acid,HA)、层黏连蛋白(laminin,LN)和Ⅳ型胶原(Ⅳ-collagen, Ⅳ-C)检测和肝脏声像图检查.结果:治疗后1年,48例患者中Child-Pugh分级和肝脏声像图检查结果较治疗前好转者分别为32例(66.67%)和21例(43.75%),血清HA、LN和Ⅳ-C水平较治疗前显著降低(P<0.05,P<0.01);治疗后2年,Child-Pugh分级评分和肝脏声像图检查结果较治疗前好转者分别为44例(91.67%)和31例(64.58%),与治疗后1年比较,差异有显著性(P<0.05),血清HA、LN和Ⅳ-C水平均较治疗前和治疗后1年显著降低(P<0.05,P<0.01).结论:长期中西医结合除铜治疗可明显改善HLD患者的肝硬化程度,坚持长期正规治疗对改善本病预后至关重要.     

The Oprah shows I would like to see

This essay addresses how Oprah's book choices are inevitably affective but not necessarily feminist. By reading Oprah's book choices as highly individualistic, I analyze how her choices might be more aggressive and more complex, thereby offering a sense of community rather than the power of individuality to her huge audiences. My argument is based on a belief in Oprah's communicative power, and especially if her book choices were invested with more complications than individual resolutions.     

电针内关和心俞对家兔急性心肌缺血的协同保护作用

目的：观察电针内关和心俞穴对家兔急性心肌缺血的协同保护作用。方法：40只家兔随机分为对照组、模型组、内关组（电针内关穴）、心俞组（电针心俞穴）、关俞组）电针内关和心俞穴）。通过耳缘静脉注射垂体后叶素复制急性缺血性心电图模型，观察电针治疗后心电图T波、ST段变化。结果：关俞组T波、ST段改善最明显（P＜0．05），缺血性心电图恢复时间最短（P＜0．05）。结论：电针心俞和内关穴对急性心肌缺血具有协同保护作用。     

Collateral Damage: An Analysis of the Achievements and Unintended Consequences of Batterer Intervention Programs and Discourse

This paper reviews and critiques two prevailing program models for batterer intervention in order to highlight both their valuable achievements and attendant costs and consequences. We analyze these batterer intervention program models at 3 levels. First, we describe the historical development and basic program components of the intervention models. Second, we trace differences in the models to their grounding in different psychological assumptions and theories about behavior change, masculinity, and violence. Third, differences between the models are mapped onto contrasting approaches to the regulation of human deviance in the criminal justice and mental health systems. Based on this analysis, we conclude that further attention to structural and contextual factors, such as class, race, economic stress, and substance abuse in explanations of domestic violence is needed, together with alternative approaches to collaboration between victim advocates and batterer intervention providers.     

抑郁症心理治疗新进展

抑郁症的治疗一直以来具有多元化的特点,目前的发展趋势是药物治疗合并心理治疗。就心理治疗而言,治疗方法在不断改革创新。国内以内观、意向对话为代表。国外的研究一方面在澄清各种心理治疗之间不同的治疗作用,同时也在积极地将心理学后现代的理论成果运用于抑郁症的治疗,比如积极心理学、自体心理学。今后的理论研究与实践,一方面要注重总结经验,在现有的成果上进行整合性的创新;另一方面在实践中要区分不同年龄,性格以致文化背景的患者应用何种治疗方法,使抑郁症治疗更具有针对性。     

中药周期序贯疗法对子宫内膜异位症不育患者体外受精胚胎移植的影响

目的 观察中药周期序贯疗法在子宫内膜异位症(endometriosis,EM)合并不育症患者行体外授精胚胎移植(in vitro fertilization-embryo transfer,IVF-ET)过程中的治疗作用.方法 将准备行IVF-ET的EM合并不育患者随机分为对照组(28例)和中药组(25例),对照组采用...     

噬菌体在细菌性疾病诊断和治疗中的应用

从重组噬菌体法、生物扩增法、噬菌体触发的离子级联感应技术及耐药性检测4个方面阐述了噬菌体在病原菌检测中的作用;从细菌分型的角度阐述了噬菌体在病原菌分型中的应用;从活噬菌体、裂解酶、药物载体3个方面陈述了噬菌体在细菌性疾病治疗方法中的研究进展,并分析了噬菌体在应用中的优缺点,展望了今后的研究和应用前景。     

内观疗法在罪犯改造中的本土化应用

内观疗法作为一种独立的心理治疗方法,通过回顾和检讨内观者自己过往的所作所为,进行自我洞察、自我分析,以纠正自己的不良态度,改善自己的人格特征,使内观者在内观的过程中产生健康人应有的做了错事后的罪恶感、羞耻感,通过内观者对自我形象和他人形象进行调整,提高与他人的共鸣、协调和自我控制的能力,其与罪犯改造高度的适切性,决定着将其引入罪犯改造必将带来良好的效果。     

Segmental Hair Analysis—Interpretation of the Time of Drug Intake in Two Patients Undergoing Drug Treatment

The present study involved segmental testing of hair in two clinical cases with known dosage histories. Hair analysis confirmed the first patient's exposure to the prescribed sertraline and citalopram for several months. Citalopram was generally distributed along the hair shaft in accordance with the drug ingestion period. By contrast, “false” positive results were observed for sertraline in distal hair segments, corresponding to a period of no sertraline exposure, which may indicate incorporation from sweat or sebum, which transport the drugs along the hair surface. The second patient received various drugs during her treatment for brain cancer. Metoclopramide, morphine, oxazepam, paracetamol, sumatriptan, tramadol, and zopiclone, which had been part of the therapy, were all detected in the proximal hair segment. The results of these two cases indicated that results—especially concerning the time of drug intake—must be interpreted with caution and allow for the possibility of incorporation from sweat or sebum.     

Community mobilisation and HIV activism in Zimbabwe

ABSTRACT

Community mobilisation and activism is thought to encourage HIV testing and treatment and assist patient recovery. This article draws on interviews conducted with 60 people living with, and affected by HIV, in four marginalised areas of Harare, Zimbabwe. The lenses of civil society and social movements are used to analyse how people living with HIV draw on, and construct, systems of support based on the ways in which their communities know and understand the epidemic. I consider how neighbourhoods negotiate and assert community and individual needs in relation to HIV and how such systems can develop into community networks and wider coalitions. The article concludes by positing that, by interrogating official responses to the epidemic, HIV-related activism and social movements can help to domesticate formal commitments to international health protocols and compliance, particularly in terms of the intent, as well as the participatory rhetoric, of health based rights.