楚雄州当前毒品犯罪状况及对策

楚雄州的禁毒形势可以用两句话来概括 :一是禁毒斗争取得了一定成果 ;二是面临的形势依然严峻。因此 ,必须树立长期作战的思想 ,加强情报信息工作 ,有针对性地打击毒品犯罪 ,堵源截流 ,同时 ,加强禁吸戒毒 ,禁种铲毒和大麻禁种改植工作 ,搞好禁毒宣传 ,全面创建“无毒社区”。     

大蒜素对卵巢癌细胞株HO8910生长的抑制作用

目的：观察大蒜素对卵巢癌细胞株HO8910的抑制作用。方法;用不同时间不同剂量大蒜素作用于HO8910,通过肿瘤细胞药敏试验。观察肿瘤细胞存活率,并通过透射电镜观察一定剂量的大蒜素作用于HO8910一定时间后,肿瘤细胞形态的改变。结果：50-100μg/ml大蒜素可显抑制肿瘤细胞的生长。且在作用2h时即出现显的抑制,随着作用时间的延长,抑制作用愈明显,72h害到高峰,透射电镜结果显示：50μg/ml的大蒜素作用HO891024h。细胞肿胀。细胞膜破碎,胞浆脱落。细胞核裸露;小剂量（25μg/ml)则HO8910呈现细胞凋亡样改变;细胞胞浆呈空泡,染色质边集,核仁固缩,胞质呈片状脱落。结论：大蒜素可显抑制HO8910的生长,且有明显的时间及剂量效应,大剂量的大蒜素对HO8910细胞呈直接杀伤作用。而小剂量则诱导细胞凋亡。     

毒品案件主观认定中的自由心证

在并未明确和确立自由心证制度的我国,自由心证已在刑事证据审查的广大领域占有了重要的一席之地,并发挥着潜移默化的证明作用。基于毒品犯罪证据收集中的实际困难,司法人员在犯罪嫌疑人拒不认罪,并否认自己主观明知的案件中,较多地从客观证据出发,运用经验规则与逻辑规则形成自己的主观判断(心证)。然而,自由心证是否公正和理性,则取决于司法人员的学识、经验和道德操守。     

A sudden death with lung embolism after inadvertent infusion of zinc oxide shake lotion

A 74-year old woman in postoperative treatment after a colonic surgery died immediately after perfusion of about 1.5 mL of a white emulsion which was believed to contain 1% propofol via cardiac catheter into the right atrium. It was strongly suspected that a syringe with a zinc oxide shake lotion (consisting of 20% ZnO, 20% talc, 25% glycerol and 35% water) which was intended for external treatment had been mistaken for the propofol syringe. During autopsy, an anatomic cause of death could not be found. In order to exclude an intoxication and to determine the significance of the perfusion fluid in this context, toxicological and histological investigations were performed. Propofol and other drugs applied to the patient were found in therapeutic or sub-therapeutic range. However, in comparison to a control case, the zinc concentrations determined by AAS were about 200 times higher in lung tissue, 10 times higher in heart blood and 3–4 times higher in kidney and liver tissue. No increase was seen in venous blood. Histology showed a strong embolism of the lung tissue with birefingent sharp-edged crystals, which were identified as the talcum, and an amorphous component (ZnO). The same embolism was seen to a medium extent also in the brain sections and to a low extent in heart, liver, pancreas and kidney. Pulmonary embolism by talcum and zinc oxide was established as the cause of death which occurred by syringe swap due to insufficient security precautions in the drug administration. The results are discussed in context of pulmonary microembolism cases frequently described for drug addicts after injection of crashed talcum containing tablets.     

科学发展观下云南毒品问题探析

从科学发展观看云南的毒品问题,本质上是一个发展问题。云南毒品问题的原因是多方面的,其自身特征为:一是发展落后,特别是经济落后是云南毒品危害形势严峻的突出原因;二是边疆地域特殊是云南毒品问题最直接的外在诱因;三是民族、宗教分裂势力及境外敌对势力与毒品问题交织,使云南毒品问题非常复杂。因此,我们要站在科学发展观的高度来认识、分析和治理云南的毒品问题,从而把握本质,达到标本兼治,禁绝云南毒品的目的。     

The designer drug situation in Ibiza

A total of 137 urine samples and 46 serum samples, corresponding to 154 self-confessed designer drugs consumers in Ibiza island, were analyzed for the presence of designer drugs: amphetamine and amphetamine derivatives (methamphetamine, methylenedioxymethamphetamine (MDMA), methylenedioxyethylamphetamine (MDEA), methylenedioxyamphetamine (MDA), p-methoxymethylamphetamine (PMMA), p-methoxyamphetamine (PMA), etc.), ketamine and γ-hydroxybutyric acid. Among this population, coming both from the forensic clinic and from the emergency room of a hospital, a total of 99 cases were found positive for some designer drug. This study shows the prevalence of methylenedioxymethamphetamine (MDMA) among designer drug users, sole or in association with other drugs. Also, the mixture of MDMA with other designer drugs, ethanol and/or cocaine is shown to be more likely to produce toxic symptoms requiring clinical attendance in a hospital emergency room. These findings along with the consumption history, the concentrations of drugs and metabolites in urine and serum and the toxicological significance for the interpretation of some MDMA metabolites such as 4-hydroxy-3-methoxymethamphetamine (HMMA) are discussed in this study.     

药物不良反应纠纷处理的困惑和思考

由药物不良反应引起的医疗纠纷日益增多,由于目前没有相应的法律法规来解决此类纠纷,使患者、医院和生产厂家都感到十分困惑和无奈。要处理好药物不良反应所引起的纠纷应该:1防患于未然,积极预防药物不良反应的发生;2依法处理,企盼相关的法律法规尽快出台;3加强监测,应用网络技术加强监测和报告;4更新理念,积极筹措药物不良反应补偿基金。     

医疗机构药品缺陷责任的法律分析

药品缺陷责任法律制度关系人民群众切身利益,十分重要。我国相关法律制度十分不完善,既没有维护好受害者的权益,同时又未能将责任在责任主体间进行公平分担。现行法律制度根本无法达成以上目标,必须重新建构科学合理的药品缺陷责任制度。在此基础上,实践中医疗机构药品缺陷责任畸重的问题才能得到根本上的解决。     

Drug Views

Abstract

Substance abuse is a significant social problem and political issue. Students at a Midwestern university were surveyed on their drug views. The findings suggest that race is a statistically significant factor on students' views toward drugs. White students were more likely than non-Whites to view drugs as a pressing social issue, to consider drug use as a character weakness, and to support a punitive response to drug use. In contrast, non-Whites were more likely than Whites to view drug abuse as an illness, to support treatment as a response, to be tolerant of marijuana use, and to support legalization of marijuana. Both groups of students considered alcohol a dangerous drug. Differences associated with race remained statistically significant in multivariate analysis after controlling for age, academic standing, political affiliation, and religiosity.