化瘀温经利湿法治疗慢性盆腔炎20例临床观察

目的观察化瘀温经利湿中药对慢性盆腔炎患者的疗效及对外周血CD4^＋CD25^＋CD127^lo调节性T细胞（regulative Tcells，Treg）的影响。方法将40例慢性盆腔炎患者按随机数字表法分为化瘀温经利湿中药治疗组20例和西药对照组20例，两组均以1个月为1个疗程，均治疗1个疗程，观察临床疗效及对症状出现率的影响；采用流式细胞术检测患者治疗前后外周血CD4^＋CD25^＋CD127^loTreg的数量及其在CD4^＋T淋巴细胞中所占的比例；并检测治疗前后血沉（erythrocyte sedimentation rate，ESR）和C反应蛋白（C—reactive peptide，CRP）水平。结果与对照组比较，治疗组总有效率和CD4^＋CD25^＋CD127^loTreg表达水平显著升高，ESR、CRP及症状出现率显著降低（P〈0．05）。结论化瘀温经利湿中药治疗慢性盆腔炎的作用机制，可能与其上调CD4^＋CD25^＋CD127^loTreg表达水平，促进免疫调节，降低炎症反应有关。     

Lipidic compounds found in soils surrounding human decomposing bodies and its use in forensic investigations – A narrative review

Following decomposition of a human body, a variety of decomposition products, such as lipids, are released into the surrounding environment, e.g. soils. The long-lasting preservation in soils and their high diagnostic potential have been neglected in forensic research. Furthermore, little is known about the preservation, chemical transformation, or degradation of those human derived lipids in soils. To date, several studies identified various lipids such as long-chain free fatty acids and steroids in soils that contained decomposition fluids. Those lipids are preserved in soils over time and could serve as markers of human decomposition in forensic investigations, e.g. for estimating the post-mortem interval or identifying the burial location of a human body. Therefore, this review focuses on the current literature regarding fatty acid and steroid that have been detected in soils and associated with human body decomposition. After a short introduction about human decomposition processes, this review summarises fatty acid and steroid analysis applied in current case studies and studies related to taphonomic research. This review provides an overview of the available studies that have used fatty acids and steroids as identifiers of human decomposition fluid in soils in a forensic context and discusses the potential for developing this innovative field of research with direct application in a forensic context.