组织细胞DNA含量变化与死亡时间的相关性研究

目的研究人死后各器官组织细胞DNA降解变化规律,探讨其在推断死亡时间方面的应用价值,为推断死亡时间提供科学依据。方法已知死亡时间人尸体的心、肝、脾、肾,按死后6,12,24和48h四个时间段取材,制成石蜡切片,经Feulgen染色并图像分析;同时将各器官组织按不同时间段取材,制成单细胞悬液,应用流式细胞仪检测DNA含量。结果(1)人体各器官组织细胞经FCM检测,脾细胞核DNA随死亡时间延长呈现较好的下降梯度,而心、肝、肾,则由于自溶较快,死后6h细胞核DNA含量已很低,其变化情况与死亡时间的相关性不佳;(2)各器官组织细胞核DNA染色强度指数均随死亡时间的延长而下降。结论(1)机体死亡后,各器官组织细胞核DNA含量随死亡时间延长逐渐减少,具有一定的变化规律,其中以脾细胞核DNA含量的变化趋势与死亡时间最具相关性,肝、肾次之,而心最差;(2)方法学分析,图像分析技术(IAT)与流式细胞术(FCM)两种检测方法在研究组织细胞DNA含量变化方面,各有利弊,可互补不足。     

长春市上市公司在地方经济发展中的地位与作用

上市公司的发展和壮大为长春市地方经济的发展提供了有效的资本支持，加快了长春市经济结构的合理调整和优化组合，对长春市经济持续，快速和健康发展起到了重大作用。具体表现在：上市公司进入证券市场，拓宽了融资渠道，以上市公司为龙头，带动相关行业的腾飞。通过资本流动，加快了经济结构的调整，通过产权交易，转换了经营机制，提高了管理水平等。     

论循环型社会的内涵和意义

循环经济是解决经济系统与环境系统之间的矛盾、实现人与环境和谐发展的重要途径.循环型社会是循环经济思想的发展和深化.发展循环经济,离不开社会系统的支撑.构建循环型社会是循环经济真正实现的前提和保障.本文系统阐述了循环型社会的概念和内涵,并从理念、价值观、伦理、经济、技术等方面论述了循环型社会的特征以及与科学发展观的关系.     

Preliminary studies into fluorescent semiconductor nanorods for the detection of latent fingermarks: Size matters,shape matters

The effect of the shape of semiconductor nanocrystals on their performance for visualising latent fingermarks was investigated for the first time. Highly luminescent CdSe/CdS core/shell nanocrystals in rod and spherical shapes were synthesised in organic solvent and transferred to aqueous solution using ligand exchange. The 3-mercaptopropionic acid coated nanorods and nanospheres were characterised using electron microscopy and UV-visible absorbance and luminescence spectrophotometry. A simple and rapid development of fresh to less than a week-old natural fingermarks from 4 donors (male and female) on non-porous surfaces including glass slides, aluminium foil and germanium disks using both CdSe/CdS core/shell nanorods and spherical dots was achieved, wherein nanorods demonstrated an enhanced development of ridge details in comparison to the spherical dots.     

Evaluation of alizarin and purpurin dyes for their ability to visualize latent fingermark on porous surfaces

Anthraquinones are a group of dye with many members and a wide range of industrial uses ranging from food, textiles to printing. Even though the reactions of anthraquinone dyes with amino acids are known, they have not yet been subjected to an examination regarding their ability in fingermark detection. In the presented study, the potential of alizarine and purpurin, natural anthraquinone dyes, as a fingermark reagent was examined in comparison with ninhydrin and lawsone. Alizarin and purpurin react with latent fingermark residue on copier paper and thermal paper to yield yellow-orange coloured impressions. The products formed also display photoluminescence properties when illuminated at 440 nm viewed through red filter. Both natural anthraquinone dyes exhibited some superior properties at the development of latent fingermarks on these surfaces compared to ninhydrin and lawsone.     

Analyzing Criminal Trajectory Profiles: Bridging Multilevel and Group-based Approaches Using Growth Mixture Modeling

Over the last 25 years, a life-course perspective on criminal behavior has assumed increasing prominence in the literature. This theoretical development has been accompanied by changes in the statistical models used to analyze criminological data. There are two main statistical modeling techniques currently used to model longitudinal data. These are growth curve models and latent class growth models, also known as group-based trajectory models. Using the well known Cambridge data and the Philadelphia cohort study, this article compares the two “classical” models—conventional growth curve model and group-based trajectory models. In addition, two growth mixture models are introduced that bridge the gap between conventional growth models and group-based trajectory models. For the Cambridge data, the different mixture models yield quite consistent inferences regarding the nature of the underlying trajectories of convictions. For the Philadelphia cohort study, the statistical indicators give stronger guidance on relative model fit. The main goals of this article are to contribute to the discussion about different modeling techniques for analyzing data from a life-course perspective and to provide a concrete step-by-step illustration of such an analysis and model checking.

Information pathways into prison mental health care

Police and court liaison and diversion services provide important specialist mental health input along critical stages of the criminal justice pathway. Effective sharing of information between the services and relevant justice agencies is essential. However, various problems exist with the flow of information between agencies and services across the criminal justice pathway. This service evaluation explored how clinically relevant information is transferred, by drawing on the perspectives of prison health care staff in a large urban UK male prison. A qualitative service evaluation was conducted using semi-structured interviews with a purposive sample of 11 prison staff. The main themes included: gaps in the transfer of essential information, (particularly concerning risk and offending information); information gathering to fill these gaps; the importance of professional relationships, information sharing between agencies; and information solutions. Improving information transfer across the criminal justice pathway could prevent treatment delays and ensure more timely mental health care in prison.     

Mephitic projects: a forensic leisure science analysis of the BTK serial murders

Although it has been suggested among both forensic experts and a small number of leisure scientists that serial murder may be a form of recreational leisure, such suggestions remain largely unexplored both theoretically and empirically. Given the absence of scholarship on this possibility, this project explored and analyzed the structure and function of leisure activities within an unusual case (Dennis Rader) of serial murder. A thorough analysis of relevant case documents confirmed that serial murder itself can be experienced by the killer as a form of recreational leisure with the potential for optimal psychological experience (flow), and that various leisure activities may function in specific ways within the serial murder process. An unexpected finding in this case was that leisure, specifically project-based leisure, served to structure specific killings. Findings provide valuable new insights for forensics behavioral experts that may be used to guide future research.     

The Downsian roots of affective polarization

A growing literature studies the relationship between ideological and affective polarization. By taking a Downsian approach to affective polarization we contribute to this literature and demonstrating that affective polarization is driven by congruence between citizens and their party, relative to other parties, in the general liberal-conservative space and across a host of salient issue domains. We find robust support for our theory using individual-level national election survey data from the United States, United Kingdom, Germany, and Finland. Moreover, we find that ideological differences inform affective polarization independently from partisan identifications and that they drive more out-party animosity than in-party affinity. These findings have implications towards a more unified understanding of the citizen determinants of affective polarization and the role ideology plays in shaping the views held by partisans across democracies.     

Development of latent fingermarks on thermal paper: Preliminary investigation into use of iodine fuming

Thermal paper finds its extensive use in the modern day life and could act as a vital piece of physical evidence carrying latent fingermarks. A large number of citations are available in literature suggesting various techniques to develop these marks but all are suffering with one or the other drawbacks such as complex and cumbersome procedure, pre- or post-treatment, background coloration and efficiency to develop aged fingermarks. In present study, a very simple and novel method involving iodine fuming has been suggested to develop fingermarks which were not only permanent but also without any background coloration. The suggested method does not involve any pre- or post-treatment of the substrate and was able to develop very old fingermarks (upto >1 year). In this study an attempt has been made to explain the reaction mechanism of the process. In case of different types of thermal papers, presence of different substituents on leuco dye (lactone ring) structure resulted in development of different colored fingermarks upon reaction with iodine. Sebaceous material laden marks have been found to be more intensely developed as compared to eccrine marks, and the difference was more pronounced in case of aged fingermarks.