大财团主义(Corporism):摧毁文明社会的体制弊病

大财团主义的发展及其对政府的专制统治是文明社会的弊病.它导致了危机的增加和世界大多数人口的贫困,甚至将会导致全世界的毁灭.为了人类文明和经济社会的发展,就必须消除这一弊病,制止"大财团企业"对文明和人性的统治.     

大鼠挫伤肺组织中水通道蛋白1表达变化

目的探讨水通道蛋白1（aquaproin 1,AQP1）在大鼠挫伤肺组织中的表达变化及其与肺水肿的关系。方法将SD大鼠随机分为实验组和对照组,制备肺挫伤模型,用免疫组织化学方法检测肺组织中AQP1的分布和表达变化。结果肺挫伤后1和3h肺组织出现水肿、出血,炎性细胞浸润,5h炎性反应进一步加重。AQP1表达在挫伤后1、3和5h均明显高于对照组（P〈0．01）,随着伤后时间延长,水肿加重,AQP1持续上升。正常AQP1主要分布在支气管和肺泡壁的毛细血管内皮细胞及间质细胞,挫伤后肺AQP1的表达部位未发生改变,但积分光密度值（intergrated optical density,IOD）差异有统计学意义（P〈0．01）。结论挫伤肺组织可能存在AQPs的基因表达调控失衡,导致大量水的异常跨膜转运以及在肺组织中的异常聚集,这可能是挫伤肺组织水肿形成原因之一。     

我国传染病防治领域公民权利保护的立法进展与思考

2003年以来,我国传染病防治领域公民权利保护的法制建设取得了较大进展,生命权、健康权的维护不断强化,人身自由权的限制及其生活保障更加人性化,财产权的政府处置权力与补偿义务逐渐对等化,知情权的运用逐步制度化、个体化,受救助权的实现形式日益多元化,隐私权的规定越来越具体化,不受歧视权的保护范围适度细化。但是,为了进一步完善传染病防治领域的公民权利保护,建议：加快公民权利保护均等化的立法步伐,关注公民权利保护的法律法规可操作性,提高公民维护自身权利的法律意识,汲取国外依法保护公民权利的有益经验。     

正清风痛宁关节内注射治疗强直性脊柱炎髋关节病变30例

目的:观察髋关节注射正清风痛宁注射液对强直性脊柱炎髋关节病变的疗效.方法:将2005年3月至2008年3月中国人民解放军广州军区广州总医院中医科门诊和病房治疗的强直性脊柱炎并伴有髋关节病变患者随机分成观察组(30例)和对照组(25例),观察组采用常规药物治疗,并采用正清风痛宁注射液髋关节注射,对照组采用常规药物治疗,比较治疗前和治疗后1个月的目测类比评分(visual analog scale, VAS)、Bath强直性脊柱炎功能指数(Bath ankylosing spondylitis functional index,BASFI)、Bath强直性脊柱炎疾病活动指数(Bath ankylosing spondylitis disease activity index, BASDAI)、血沉(erythrocyte sedimentation rate, ESR)、C反应蛋白(C-reactive protein, CRP).结果:两组患者治疗后VAS、BASFI、BASDAI、ESR和CRP均比治疗前显著降低(P<0.05),而且观察组VAS和BASFI的改善情况显著优于常规药物对照组(P<0.05).结论:常规药物治疗基础上联合应用正清风痛宁注射液治疗AS髋关节病变在改善患者局部疼痛和功能方面明显优于单纯常规药物治疗.     

Postmortem Diagnosis of Fatal Hypothermia by Fourier Transform Infrared Spectroscopic Analysis of Edema Fluid in Formalin-Fixed,Paraffin-Embedded Lung Tissues

The goal of this study was to investigate whether pulmonary edema could become a specific diagnostic marker for fatal hypothermia using Fourier transform infrared (FTIR) spectroscopy in combination with chemometrics. The spectral profile analysis indicated that hypothermia fatalities associated with pulmonary edema fluid contained more β-sheet protein conformational structures than the control causes of death, which included sudden cardiac death, brain injury, cerebrovascular disease, mechanical asphyxiation, intoxication, and drowning. Subsequently, the results of principal component analysis (PCA) further revealed that the content of β-sheet protein conformational structures in the pulmonary edema fluid was the main discriminatory marker between fatal hypothermia and the other causes of death. Ultimately, a robust postmortem diagnostic model for fatal hypothermia using a partial least-squares discriminant analysis (PLS-DA) algorithm was constructed. Pulmonary edema fluid spectra collected from eight new forensic autopsy cases that did not participate in the construction of the diagnostic model were predicted using the model. The results showed the causes of death of all these eight cases were correctly classified. In conclusion, this preliminary study demonstrates that FTIR spectroscopy in combination with chemometrics could be a promising approach for the postmortem diagnosis of fatal hypothermia.     

The Causes of Disease Impact Denialism in Nicaragua's Response to COVID-19

The response of the Nicaraguan government to the COVID-19 emergency is an extreme case of disease denialism. Such denialism is a major threat to public health, so understanding the sources of this attitude is paramount. Three explanations are offered: (a) the autonomous logic of a polarised political conflict; (b) an explanation based on an economic rationale; and (c) the regime's mystical and religiously-inspired discourse. The denialist response of the government is inexplicable without referring to the characteristics of the political regime, its political discourse and its recent developmental trajectories since the massive 2018 protests and the ensuing political conflict.     

The Personal Is Political Yet Again: Bringing Struggles between Gender Equality and Gendered Next of Kin onto the Feminist Agenda

In spite of feminist criticism of the welfare state, Norwegian society is frequently perceived as gender-equal. As a truism of public discourse, gender equality affirms a neoliberal understanding of individuals as able to act independently and to freely choose their course in life. This article disrupts that truism with an analysis of a transitional process that occurred to a seemingly free and gender-equal married woman whose everyday life took an unexpected turn at the age of 50 when her husband was diagnosed with Alzheimer’s disease. Using an abductive method, we construct a narrative with this woman as the main character. We then use the narrative as an optical device for scrutinizing encounters between the notions “free and gender-equal woman” and “gendered next of kin”, analysing the situated becoming of gender and understanding the encounters’ potential for agency and resistance. The inquiry brings a pattern of gendered encounters into being, demonstrating how a seemingly free and gender-equal woman’s strength and independence become subordinating weaknesses in encounters with the welfare state. This paradox raises questions about the politics of everyday life in a presumably gender-equal society, brings new struggles onto the feminist agenda, and demands that the personal becomes political yet again.     

重大传染病疫情报告与信息披露制度完善的思考——以《传染病防治法》修改为中心

发现—报告—披露,是重大传染病应急管理的首要阶段和首要任务.现行《传染病防治法》规定的重大传染病疫情报告与信息披露制度,在立法目的、体制机制、保障措施方面存在不足.为保障重大传染病疫情报告与信息披露的及时性和准确性,《传染病防治法》的立法目的应当保护"安全"和"秩序"目的.应当确立医师对重大传染病疫情报告的法定义务、公...     

麝香保心丸对冠心病患者外周血脂联素和瘦素水平的影响

目的 初步探讨麝香保心丸对冠心病患者外周血脂联素和瘦素水平的影响。方法 将124例确诊的冠心病患者分为麝香保心丸治疗组（61例）和常规治疗组（63例）,同时选择冠状动脉造影正常的患者122例为对照组,正规服药1个月后,通过酶联免疫吸附试验检测3组患者外周血脂联素和瘦素水平的变化。〖JP〗结果 治疗前病例组（即常规治疗组和麝香保心丸组）脂联素水平显著高于对照组,瘦素水平显著低于对照组,差异均有统计学意义（P<0.05）;与治疗前比较,麝香保心丸组和常规治疗组患者外周血脂联素水平显著升高（P<0.05）,瘦素水平显著下降（P<0.05）,且前者治疗后外周血脂联素升高值和瘦素降低值显著大于后者（P<0.05）。结论 脂联素、瘦素是冠心病的预测因子,麝香保心丸可降低冠心病患者外周血瘦素水平而升高脂联素水平。     

大鲵体表溃烂病的病理组织学观察

通过病理切片和HE染色技术,对自然发生体表溃烂病大鲵的皮肤、肌肉、肝、脾、肺、胃肠道、肾等器官的病理组织学变化进行了观察.结果显示,肠道黏膜层、黏膜下层及浆膜层有大量炎性细胞浸润,黏膜上皮细胞大量坏死;肝中央静脉扩张淤血,肝细胞肿胀,体积增大,部分肝细胞胞浆及胞核淡染、溶解、消失,只剩下细胞轮廓,肝间质充满大量淋巴细胞、单核细胞等炎性细胞;肾间质出血,大量红细胞浸润,肾小球毛细血管严重扩张、充血,肾小囊扩张,部分肾小囊内可见均质红染的蛋白样物质,肾小管上皮细胞空泡变性,部分肾小管上皮细胞坏死、溶解、消失,管内有大量管形出现;脾实质细胞弥漫性坏死;肺泡腔内充满数量不等的红细胞;肌肉可见间质水肿,间隙增宽,肌纤维零星分布;部分肌细胞肌浆凝固、红染,有的肌细胞胞浆溶解成蜂窝状,甚至胞浆大量消失,只剩下肌膜.表明,患病大鲵除体表皮肤肌肉变化外,肝、脾、肾等重要器官均出现不同程度的病理变化.