Colchicine Extract Suicidal Lethal Poisoning Confirmation Using High‐Resolution Accurate Mass Spectrometry: A Case Study

A case of suspected acute and lethal intoxication caused by colchicine has been reported. The woman was hospitalized after her suspicion of suicidal poisoning by a rare autumn crocus (Colchicum autumnale). Suspected colchicine poisoning was confirmed using a novel UHPLC method with a modern reversed‐phase stationary phase with a sub 2‐micron superficial porous particle size combined with a QTOF mass spectrometer. Sample preparation procedure included the addition of propiverine as internal standard, protein precipitation using methanol and solid phase extraction. High‐resolution MS only and targeted MS/MS modes are reported for the qualitative analysis and screening of other potential drugs of abuse in blood samples. All Ion MS mode was used for quantitative determination of colchicine afterward. The concentration of colchicine in the blood sample was approximately 41 ng/mL, and more than 200 μg/mL of the plant extract used for the suicide.     

东北三省提升对俄经贸合作水平值得思考的几个问题

中俄经贸合作形势大好,这为东北三省振兴老工业基地提供了新机遇。但是,近年来东北三省对俄经贸合作不尽如人意。要改变这种状况,使对俄经贸合作登上新台阶,达到较高水平,必须对其意义有新的认识,开拓新的发展思路。     

芦根中甾体的GC-TOFMS鉴定

目的：提取并测定芦根中甾族化合物的成分和相对含量。方法：采用气相色谱．飞行时间质谱法进行测定分析。结果：芦根提取物中含有4种甾体化合物。结论：该鉴定方法对药物成分的结构分析和临床用药具有指导意义。     

Classification of Opium by UPLC‐Q‐TOF Analysis of Principal and Minor Alkaloids

Opium is the raw material for the production of heroin, and the characterization of opium seizures through laboratory analysis is a valuable tool for law enforcement agencies to trace clandestine opium production and trafficking. In this work, a method for opium profiling based on the relative content of five principal and 14 minor opium alkaloids was developed and validated. UPLC‐Q‐TOF was adopted in alkaloid analysis for its high selectivity and sensitivity, which facilitated the sample preparation and testing. The authentic sample set consisted of 100 “Myanmar” and 45 “Afghanistan” opium seizures; based on the data set of the 19 alkaloid variables in them, a partial least squares discriminant analysis classification model was successfully achieved. Minor alkaloids were found to be vitally important for opium profiling, although combined use of both principal and minor alkaloids resulted in the best geographical classification result. The developed method realized a simple and accurate way to differentiate opium from Myanmar and Afghanistan, which may find wide application in forensic laboratories.     

Minimizing the cost of dispatch delays by holding patrol cars in reserve

At many police departments high-priority callers sometimes incur undue delays that could be avoided by the use of a differential response strategy that takes full account of the different costs of delay for different priority calls. In this article we examine such a strategy, in which lower-priority callers may not be served immediately, even though some response units are available. Arriving priorityi callers are queued whenever the number of busy patrol units equals or exceeds the cutoff number for that priority. Our purpose is (1) to find a practical way of choosing the set of cutoff numbers that will minimize the expected total cost of delays for the entire system and (2) to use that method to investigate how the optimal set of cutoffs changes in response to changes in several important variables, including the relative costs of delay for different priorities, the overall workload, and the relative frequencies of different priority calls.     

从违法征地到违规用警——“征地型”群体性事件研究

违法征地是农村“征地型”群体性事件频发的根源。征地农民因权益受损往往护地抗争,地方政府惯常做法是把公安机关放在处置一线,警民对立使冲突升级,最终形成“政府违法征地→农民抗争→政府违规用警→警民冲突”局面。要真正做到慎用警力妥善处置此类事件,从根本上防止因用警不当导致冲突升级、发生流血伤亡事件,关键在于坚决遏制违法征地。     

示范诉讼对解决航班延误纠纷的启示

由航班延误引发航空运输承运人及其代理人与旅客、托运人之间的纠纷愈演愈烈。国内各大机场都出现了乘客在遇到航班延误后要求高额赔偿、占机等过激行为,导致航空公司声誉受损、社会影响不佳。因航班延误导致的诉讼也日益增多,现有的司法解决方法对纠纷解决显得捉襟见肘。示范诉讼以较小的诉讼规模解决因航班延误所引起的群体性纠纷中共通的事实或法律问题,为乘客提供正当有效的司法维权途径,并促使当事人在裁判外达成和解,有利于纠纷的妥当解决。     

From Career Girl to Sexy Stewardess: Popular Culture and Women’s Work in the Canadian and American Airline Industries

This article examines three popular renditions of female flight attendants in Canada and the United States in teen fiction, film, and advertising, with attention to representational shifts from the 1940s to the 1970s. Our analysis demonstrates that the more sexualized image of the 1960s was a significant departure from the more complicated immediate postwar presentation of the flight attendant as a resourceful and capable career girl, albeit one still constrained by dominant notions of white, middle-class femininity. Created by management decisions in the face of increased capitalist competition, in concert with the influence of popular culture and gender ideology, the sexy stewardess altered the workplace environment for female flight attendants, but the legacy of earlier popular culture may well have aided their resistance to sexualization.     

试析中国资本外逃

本文通过分析国际收支平衡表误差与遗漏项数据的直接采用及与进出口贸易总额的比例来反映资本外逃的规模.同时又对其影响及原因、途径等进行了较为详尽的分析以图揭开资本外逃的神秘面纱.     

劳务派遣中雇主责任分配制度构建

在企业利润最大化目标的驱使下,劳务派遣以其低风险、低成本的特性得到用工单位的广泛青睐。其规模和比例不断扩大,并趋向主流化。但对劳务派遣中雇主角色定位以及雇主责任的分配存在较大争议。立法亦未给出明确的规定。劳务派遣规模的扩大与有关雇主责任法律规定的不足矛盾突出,派遣劳动者的权益得不到保障。应当立法明确派遣方与要派方的＂共同雇主＂身份,规定各自应承担的雇主责任,以按份责任为主,连带责任为补充,并对对方履行雇主责任互负担保义务。