儒家修身理论的函数矩阵分析

儒家传统修身理论 ,内容十分丰富 ,尽管有不可弥补的缺陷 ,但其中有许多内容 ,直到今天也仍然没有失去它价值的因子。儒家传统道德关于理想人格的道德构成 ,理想人格和修身路径的函数关系 ,“三纲”、“八目”的矩阵结构等 ,对当前思想政治教育都有着积极的借鉴作用     

基质金属蛋白酶3研究进展及其法医学意义

基质金属蛋白酶3是基质金属蛋白酶家族的重要成员,能够降解多种细胞外基质成分,参与组织形态发生、损伤修复、炎症反应等一系列生理、病理过程,并在风湿性关节炎、动脉粥样硬化、乳腺癌等疾病和肿瘤的发生及进展中发挥重要作用。新近的研究表明基质金属蛋白酶3可能是凋亡神经元与小胶质细胞间一种重要的信号传导分子,它通过激活小胶质细胞加剧阿耳茨海默病、帕金森病中神经元变性。此外基质金属蛋白酶3基因启动子区域5A/6A多态性与心肌梗死的发生风险相关,且血浆中基质金属蛋白酶3的浓度在心肌梗死前后存在差异,有望成为法医学鉴定中诊断心肌梗死的辅助指标。脑损伤后基质金属蛋白酶3的表达发生改变,提示其在神经组织修复、突触发生过程中具有重要作用,阐明脑损伤后基质金属蛋白酶3表达变化规律,可能提供一种推断脑损伤时间的新指标。     

固相微萃取技术的进展

衍生化顶空固相微萃取是将样品衍生化和顶空固相微萃取结合,使顶空固相微萃取技术扩展到难挥发性样品分析中。作者就衍生化顶空固相微萃取的发展历史、衍生化反应类型,以及在生物基质、水基质内痕量物质检测研究中的应用进行了综述。     

Does Socio-Economic Development Go Hand-in-Hand With Coutry＇s Institutional Quality？ The Case of Poland

The reviewed theories and worldwide empirical studies suggest that institutions affect economic growth and development, and vice versa. There is, however, little research examining the association of institutions with nations＇ socio-economic well-being in the post-communist countries of Central and Eastern Europe. This research fulfills this gap by exploring empirically institutional determinants of Poland＇s development over the period 1990-2011. The study relies on the concept of institutional matrix proposed by the New Institutional Economics. The purpose is to check the relationship between several indicators of economic and sustainable development （per capita Gross Domestic Product, Gini coefficients, Genuine Savings, the Happy Planet Index, and the Global Competitiveness Index） and institutional measures （the Worldwide Governance Indicators, the Economic Freedom of the World Index, Contract-intensive Money ratio）. To quantify those interrelations, correlation and regression analysis are used. The data are from Eurostat, the World Bank, National Bank of Poland, the Fraser Institute, the World Economic Forum, and the New Economic Foundation. The hypothesis is that the better institutions in Poland are associated with higher levels of economic growth and development. The findings provide less, than expected, evidence of strong linear relationship between the quality of institutional matrix and national development indicators in Poland.     

“一委一行两会”格局下中国金融监管协调框架探析

金融监管协调以防范系统性风险、维护金融体系稳定为最终目标,是金融监管体制的重要组成部分。自2018年3月以来,中国的金融监管体制呈现出"一委一行两会"的新格局,对金融监管协调提出了更高的要求。本文基于金融监管协调的国际经验,从中央部门协调、央地协调及金融科技发展的角度,分析了当前中国金融监管协调面临的障碍,并根据"矩阵式"管理的思路提出了解决方法并就此构建了相应的金融监管协调框架。本文提出在纵向上应强化央行的核心地位,发挥金融委的协调作用,明确央地权责及目标,强化属地责任;在横向上应重视跨部门协调、统筹金融业综合统计,同时还应与法律建设同步,及时跟踪科技发展,以期更好地发挥金融监管协调的作用。     

Time‐dependent Expression of MMP‐2 and TIMP‐2 after Rats Skeletal Muscle Contusion and Their Application to Determine Wound Age

The ability to determine vitality and estimate the survival period after a wound is critical in routine forensic practice. The mRNA levels of MMP‐2 and TIMP‐2 were examined using quantitative real‐time RT‐PCR to determine the age of a wound. Furthermore, the colocalization of them with Macrophage Marker, respectively, was detected by double immunofluorescence, and a standardized rat model of skeletal muscle contusion was established. In the antemortem contused groups, a large number of macrophages showed positive staining for MMP‐2 and TIMP‐2, and the expression of MMP‐2 and TIMP‐2 mRNA increased sharply at 3 days postinjury, with relative quantities of 5.75 and 2.98. No samples in the other groups showed relative quantities of >5.75 and 2.98; therefore, relative quantities exceeding 5.75 and 2.98 were strongly indicated 3 days after contusion. In addition, there was a significant decrease in the relative quantity in the postmortem contused groups, indicating that they were useful for diagnosing vitality.     

大鼠脑挫伤后基质金属蛋白酶3的表达

目的 检测脑挫伤修复过程中基质金属蛋白酶3(matrix metalloproteinase-3,MMP-3)的表达,探讨其表达规律与损伤时间的相关性.方法 将大鼠分成对照组、假手术组和脑挫伤组.应用免疫组织化学技术和蛋白质印迹(Western blot)方法检测脑挫伤后不同时间脑组织中MMP-3的表达变化. 结果免疫组化结果:对照组及假手术组脑组织未见MMP-3阳性染色;伤后6h组脑组织出现MMP-3阳性染色,此后24h内染色逐渐增强,伤后5 d阳性细胞数及染色强度均达高峰,随之下降,伤后14d仍有少量MMP-3表达.Western blot结果:对照组及假手术组脑组织未见MMP-3阳性染色;挫伤后6h组出现MMP-3表达,随后表达量逐渐上升,5d达到高峰,以后逐渐下降,14d仍有表达.结论 大鼠脑挫伤修复过程中MMP-3的表达呈时序性变化规律,可望用于脑挫伤时间的推断.     

阳和平喘颗粒对慢性哮喘大鼠气道炎症及血清基质金属蛋白酶2和9水平的影响

目的观察阳和平喘颗粒对慢性哮喘大鼠血清中基质金属蛋白酶-2(matrix metalloproteinases-2,MMP-2)、MMP-9及气道炎症的影响。方法取50只清洁级SD大鼠,随机分为正常组,模型组,阳和平喘颗粒低剂量、高剂量组,地塞米松组。采用卵清蛋白致敏激发哮喘。采用苏木精-伊红染色观察哮喘大鼠肺组织病理形态变化,光镜下计数支气管肺泡灌洗液中各炎性细胞,采用ELISA法检测血清MMP-2,MMP-9水平。结果光镜下发现,阳和平喘颗粒低、高剂量组及地塞米松组大鼠气道壁黏膜及周围肺组织炎性细胞浸润较模型组减少,气道上皮细胞增生较模型组明显减轻。与模型组比较,阳和平喘颗粒高剂量组和地塞米松组肺泡灌洗液中细胞总数、各炎性细胞数量及血清MMP-2和MMP-9水平明显降低(P0.05),而阳和平喘颗粒低剂量组肺泡灌洗液中细胞总数、各炎性细胞数量以及血清MMP-2均无显著变化(P0.05)。结论阳和平喘颗粒抑制哮喘气道炎性反应与降低血清MMP-2、MMP-9水平有关。     

The British Election Study 2015 general election constituency forecast

This paper develops a votes-to-seats nowcast model using individual level data from the British Election Study Internet panel to model the flow of the vote between 2010 and 2015. Transition matrices for each constituency are calculated using multinomial models of flows between 2010 origins and 2015 destinations. Respondents are reweighted to the polling average for England, Scotland and Wales and are further reweighted using predicted turnout to downweight respondents who are less likely to vote. The forecast performed poorly in 2015 because of polling errors and because the “Ashcroft” constituency vote intention question overestimated the Liberal Democrat incumbency effect. Without these errors, the forecast would have come much closer to the result but would still have underestimated the Conservatives' seats.     

性别气质与性别霸权——对康奈尔男性气概相关理论的再思考

1995年，康奈尔在性别研究领域提出了“多样性男性气概”及“支配性男性气概”的概念及框架，但却缺少对于“女性气质”相关概念的适应性研究；我们将朱迪斯·巴特勒的性别矩阵理论引入康奈尔的理论框架，从而在新的框架中，使“男性气概”与“女性气质”不仅相互区别而且相互补充；而异性恋欲望则成为性别矩阵中联结“男性气概”与“女性气质...