Comparative Analysis of the Chemical Profiles of 3,4-Methylenedioxymethamphetamine Based on Comprehensive Two-Dimensional Gas Chromatography-Time-of-Flight Mass Spectrometry (GC × GC-TOFMS)*

Abstract: The chemical profiling of illicit drugs is an important analytical tool to support the work of investigating and law enforcement authorities. In our work, comprehensive two‐dimensional gas chromatography–time‐of‐flight mass spectrometry (GC × GC‐TOFMS) combined with nontargeted, pixel‐based data analysis was adapted for the chemical profiling of 3,4‐methylenedioxymethamphetamine (MDMA). The validity and benefit of this approach was evaluated by analyzing a well‐investigated set of MDMA samples. Samples were prepared according to a harmonized extraction protocol to ensure the comparability of the chemical signatures. The nontargeted approach comprises preprocessing followed by analysis of variances as a fast filter algorithm for selection of a variable subset followed by partial least squares discriminant analysis for reduction to promising marker compounds for discrimination of the samples according to their chemical profile. Forty‐seven potential marker compounds were determined, covering most of the target impurities known from the harmonized one‐dimensional profiling as well as other compounds not previously elucidated.     

故意伤害罪新论

由于我国刑法只规定一个伤害故意,因此,当行为人出于轻伤的故意导致他人重伤结果,应当怎样处罚,不仅在刑法理论中没有一个统一的基准,在司法实践中也是见仁见智。实施暴力行为,导致被害人重伤或死亡的,应当属于故意伤害罪的结果加重形态。在故意伤害的情况下,即便有被害者的承诺,由于作为伤害的社会意义并没有变更,因此,不能阻却构成要件的符合性。但是,基于被害者承诺的违法性的阻却,在某种情况下可以成立。阻却违法性的判断,应当根据被害者处分自己身体的安全这一法益,是否具有社会相当性而进行。针对同时伤害的情况,不应认定为共同伤害。     

Comparison of two methods for isolating DNA from human skeletal remains for STR analysis

Abstract: The quality and efficiency of a standard organic DNA isolation method and a silica‐based method using the QIAGEN Blood Maxi Kit were compared to obtain human DNA and short tandem repeats (STRs) profiles from 39 exhumed bone samples for paternity testing. DNA samples were quantified by real‐time PCR, and STR profiles were obtained using the AmpFlSTR^® Identifiler^® PCR amplification kit. Overall, the silica‐based method recovered less DNA ranging from 0 to 147.7 ng/g (average 7.57 ng/g, median = 1.3 ng/g) than did the organic method ranging from 0 to 605 ng/g (average 44.27 ng/g, median = 5.8 ng/g). Complete profiles (16/16 loci tested) were obtained from 37/39 samples (95%) using the organic method and from 9/39 samples (23%) with the silica‐based method. Compared with a standard organic DNA isolation method, our results indicate that the published silica‐based method does not improve neither the quality nor the quantity of DNA for STR profiling.     

Watch for those fragments of evidence: the use of an automatic timepiece to help correlate a helicopter crash site from the Vietnam War

This case study illustrates the use of the date function on an automatic wristwatch to help identify a Vietnam War helicopter crash site. The location of a crash incident can sometimes be uncertain because of inadequate or inaccurate wartime records and the passage of time. Artifacts recovered from a prospective crash scene are regularly used to correlate the loss incident. In this case study, a recovered automatic watch displayed a date 2 days later than the reported loss incident. Although the date conflicts with the aircraft crash incident report, it is observed that a fully wound automatic watch continues to work for c. 2 days after movement of the watch ceases. Thus, the watch's date in fact correlates with the aircraft crash incident report. It is noted that automatic watches may also be used to date scenes of crime.     

Decaying Mouse Volatiles Perceived by Calliphora vicina Rob.‐Desv.

Volatiles emitted by decaying human remains are in the focus of recent research. The identification of core volatiles in this field is of high importance, because cadaveric volatiles generally show high variation. In this study, the volatile profiles of five mice (Myodes glareolus) were sampled with charcoal filter tubes from their time of death until advanced decay. Eleven compounds were quantitated by means of gas chromatography–mass spectrometry. Electroantennographic experiments with female Calliphora vicina antennae led to the identification of dimethyl trisulfide, dimethyl disulfide, nonanal, hexan‐1‐ol, 1‐octen‐3‐ol, 3‐methylbutan‐1‐ol, and heptanal as electrophysiologically active compounds. When these were compared, dimethyl trisulfide (17 ng/μL) and dimethyl disulfide (11 ng/μL) were found to be emitted in higher concentrations. The roles of these compounds and nonanal as core volatiles for cadaver detection or postmortem time determination and their correlation to the stages of decay and the accumulated degree days are discussed.     

Family Group Conferencing and Re‐Offending Among First‐Time Juvenile Offenders: The Indianapolis Experiment

Restorative justice processes, and family group conferences in particular, have become increasingly common in justice system practices across the globe. There has also been significant scholarly interest. Yet, with several notable exceptions, much of the research has been characterized by relatively weak designs, and questions related to the impact of family group conferences on re‐offending remain unanswered. This research is intended to begin to address these issues. The study is based on an experiment conducted in Indianapolis, Indiana whereby young, first‐time‐offending youths were randomly assigned to either a family group conference or one of a number of court‐ordered diversion programs. Nearly 800 youths participated in the experiment, and the cases were tracked for 24 months following their initial arrest. Survival analysis techniques were used to compare prevalence patterns of re‐offending among the treatment and control groups. The results indicated a significant difference between the two groups with the control group experiencing higher rates of failure (re‐offending). The differences were most pronounced during the period of 3–8 months following the initial arrest. Incidence rates were also compared. Assignment to the treatment group was negatively related to incidence of offending. Given the consistent finding of victim benefits in restorative justice processes, the results suggest that conferences hold promise as an effective intervention, at least for young first‐time offenders, and warrant continued experimentation.     

Timing is everything: a quantitative study of presidentialist regime dynamics in Eurasia, 1992–2016

Why do some countries with presidentialist constitutions feature more political closure than others at a given time? A quantitative study of post-Soviet countries since independence finds that much of the observed variation in political closure reflects timing, or the particular point at which a country happens to be within a regime cycle, rather than structural or other factors usually cited to explain regime change. Specifically, how much time a president has had to coordinate rivalrous networks around his or her authority is at least as strong a predictor of the level of regime closure as are economic development, economic growth, resource rents, proximity to Europe, and key cultural factors, even when controlling for the level of closure in the preceding year. This pattern is not found among countries with divided-executive constitutions, indicating it is related to the constitution rather than a general phenomenon.     

网络电信诈骗犯罪帮助取款行为的定性——以两个文件存在的冲突为切入点

关于在网络电信诈骗犯罪中帮助取款行为,在《关于办理诈骗刑事案件具体应用法律若干问题的解释》和《关于办理电信网络诈骗等刑事案件适用法律若干问题的意见》两份文件中均有体现,但是二者对于帮助取款行为的认定存在冲突,表现为对"明知"的内容和程度的认定有差异、帮助取款行为的时间节点的认定不同、对诈骗罪既未遂标准判定不同。网络电信诈骗帮助取款行为定性的路径选择是:对"明知"内容和程度的认定进行类型化判断;对帮助取款行为介入的时间节点进行类型化划分;以"失控说"作为判断诈骗罪既未遂的标准。     

The British general election: Synthetic forecasts

Election forecasting work, in Britain and elsewhere, has been confined mainly to traditional approaches – statistical modeling or poll-watching. We import a new approach, which we call synthetic modeling. These models, developed out of forecasting efforts from the American 2012 presidential election, we are currently testing in a comparative European context. In this exercise, we apply the strategy to forecasting British general elections, in particular the upcoming 2015 contest. These synthetic forecasts come from hybrid models blending structural knowledge with contemporary public opinion. We generate ongoing nowcasts, from six months prior, to one month before, Election Day itself.