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1.
测定了痢疾杆菌福氏 2a 30 1株与喹喏酮类药物耐药性相关的 gyrA基因和 parC基因的序列 ,并对其环丙沙星耐药诱变株的 gyrA和 parC基因喹喏酮类药物耐药性决定区 (QRDR)序列进行了测定分析。结果表明 ,痢疾杆菌福氏 2a 30 1株 gyrA和 parC基因分别为 2 6 2 5bp和2 2 5 6bp ,环丙沙星诱导的耐药菌 gyrA基因QRDR(2 4 5bp)发生氨基酸残基 6 9 Ala→Val和 87 Tyr→Asp改变 ,parC基因QRDR(2 37b)发生氨基酸残基 79 Ala→Asp、84 Ala→Glu和 85 Pro→Ala改变。这一研究结果对认识痢疾杆菌喹喏酮类药物耐药性的分子机理具有重要意义  相似文献   
2.
用K B法对52株动物源性金黄色葡萄球菌进行了 17 种抗生素耐药性检测。结果,试验菌对16种抗生素的耐药率达 19.2%~84.6%,耐药率最高的为氨苄青霉素,最低的为头孢曲松;其中对12种抗生素的耐药率在50.0%以上;在52株金黄色葡萄球菌中最少的耐 2 种抗生素,最多的耐15种抗生素,表明临床分离的金黄色葡萄球菌株均表现高水平耐药和多重耐药;受试菌均对万古霉素敏感。  相似文献   
3.
目的:观察复方中药制剂芪丹通脉片对健康犬心脏冠状动脉血流量及阻力的影响,方法:分离犬的冠状动物左旋支及主动脉根部,放置电磁流量计探头,测定不同药物在给药前后不同时刻碱诉冠状动脉血流量,计算冠状动脉阻力。结果:芪丹通脉片高剂量(生药2g/kg)能明显增加冠状动脉血流量,减少冠状动脉阻力,结论:芪丹通脉片能够增加冠状动脉血流量,调整和改善心肌供血,为缺血性心脏病的治疗提供了实验论据。  相似文献   
4.
贪污、贿赂犯罪嫌疑人通常以拒供、谎供、翻供等方式来对抗对其罪行的侦查、讯问,侥幸、畏罪、矛盾、抗拒等心态是支撑上述诸种对抗方式产生的内在心理基础.犯罪心理学研究表明,检察人员在初查、第一次讯问等关键阶段对犯罪嫌疑人有意设定的心理限制,将带来对此类案件的突破.  相似文献   
5.
在中国法治建设中需要积极恢复与倡导人权和抵抗权精神,进一步将各项法律中规定的抵抗权(抵制权)落实到位。在此方面,对罗马公法的抵抗权原理与儒家法文化传统的抵抗权精神进行比较研究具有重要的理论价值和现实意义,主要体现为人民主权论与民本民胜论、良心博爱论与自然人权论、道法天刑论与自然法思想、批判暴政与抵抗不义的比较研究。  相似文献   
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7.
During the late 1970s, members of the Polish democratic opposition revised and reinterpreted key elements in the Polish past in support of their contemporary ideas about Polish society and opposition. The birth of the independent press in Poland in 1976 provided these debates with a medium for wide dissemination and discussion. Analysis of democratic opposition debates in the independent press on the Polish–Lithuanian Commonwealth, historic Polish–Russian relations, and the struggle for and achievement of independence in the early twentieth century shed light on the ways in which the democratic opposition perceived Polish society and the legacy of tolerance, diversity, nationalism, and socialism within it. It also reveals the major divisions within the democratic opposition and its primary tactical proposals prior to the birth of the Solidarity trade union in 1980. Forty years later, these debates continue to reverberate.  相似文献   
8.
This study examines the semiotic resources deployed in resisting negative stereotypes of Nigeria in the international community, particularly representations of the country in the Western media. Data for the study were drawn from Nigeria’s Heart of Africa nation branding campaign. The study applies the discourse-historical approach (DHA) pioneered by Ruth Wodak of the Vienna School of CDA. DHA attempts to integrate much available knowledge about the historical sources and the background of the social and political fields in which discursive events are embedded. Further applying Reisigl and Wodak's presentation of the discursive strategies normally oriented towards understanding texts related to nations and national identities, among others, the study reveals that in appropriating the semiotic resources in the campaign, the discourse producers have predilection for the discursive strategies of mitigating negative attributes which the out-group intensifies, and highlighting positive attributes which the out-group seemingly under-reports in its representations of Nigeria. Notwithstanding the rhetorical dynamics of the semiotic resources, the study concludes that enduring national image management thrives on creating new images and associations lived by a country’s citizens rather than tries to refute old ones.  相似文献   
9.
Global production network (GPN) analysts argue that workers actively contribute to the shaping of GPNs through different forms of agency. In this contribution I extend this argument to the tactical agency of small producers. By focusing on the phenomenon of side-selling among Filipino banana contract farmers, I show that these tactics have contributed to the emergence of alternative trade networks that undermined traditional lead firm behaviour and inspired new struggles over chain governance. However, as a diverse and ambiguous group of growers engages in this tactical agency, predominantly as small capital, they also contribute to the continuation of broader dynamics of capital accumulation and labour exploitation.  相似文献   
10.
ABSTRACT

Teodor Shanin's The Awkward Class helped to launch two immensely important research directions. First, resistance by Russian peasants to modernizing agricultural policies by both Tsarist and Soviet governments opened new questions about collectivization of agriculture, and made Russian history relevant to the study of ‘developing societies.’ Second, the idea of cyclical mobility of peasant households challenged the then widely held assumption that peasants were destined to disappear. Instead of explaining ‘persistence’ of peasants, Shanin explored distinct logics of peasant households and communities. This helped to define a new inter-disciplinary field called peasant studies.  相似文献   
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