Evaluation of Purkait's triangle method for determining sexual dimorphism

The identification of sex from the skeleton is an important demographic assessment in medicolegal investigations. Rama Purkait developed a method for estimating sex using measurements from a triangle defined by three points on the proximal end of the femur using skeletal material from Bhopal, India. This method was tested with measurements on 200 Indo-European and African American adult femora from the Terry collection using discriminant function analysis to determine if Purkait's method was valuable for determining sex in Americans. A side-by-side analysis was conducted of Purkait's "triangle method" and the maximum diameter of the femoral head to determine their relative value in assessing sexual dimorphism. In the study sample a single variable from Purkait's method provided 85.5% prediction accuracy, similar to 87% for the head diameter. Combining threshold values for a single variable from Purkait's method and the femoral head diameter raised the predictability to greater than 90% for both sexes.     

小鼠皮肤切创愈合过程中磷酸化 p38MAPK 表达及其与时间的相关性

目的探讨小鼠皮肤切创愈合过程中损伤区磷酸化p38MAPK(p-p38MAPK)的表达情况,以及不同损伤时间p-p38MAPK的变化规律。方法应用免疫组织化学和Westernblot的方法检测33例小鼠皮肤切创后各个时间段p-p38MAPK表达情况。结果正常组织中有少量的p-p38MAPK表达。伤后3～12h损伤区p-p38MAPK主要表达于中性粒细胞中,1～5dp-p38MAPK阳性表达主要为单核细胞和成纤维细胞。7～14dp-p38MAPK阳性表达主要以成纤维细胞为主。阳性细胞率3～12h逐渐升高,1d有所下降,3、5d阳性细胞率保持在高水平,7～14d阳性细胞率逐渐降低。Westernblot显示各个时间段均有p-p38MAPK的表达。其中12h和3d为2个p-p38MAPK含量的高峰。结论在小鼠切创愈合过程中p-p38MAPK在损伤区对诱导中性粒细胞、单核细胞和成纤维细胞的凋亡起重要的作用,同时p-p38MAPK的规律性表达可用于损伤时间的推断。     

FTIR图像—单点模式法无损鉴别不同品牌激光打印机墨粉色痕

利用傅里叶红外图像系统,采用单点模式对收集到的八种品牌激光打印机墨粉色痕进行红外扫描,采集样品红外光谱,并对其中两种样品红外光谱进行二阶导数运算,得到对应的二阶导数光谱。实验表明,该方法可有效区分不同品牌激光打印机墨粉色痕,并可为其他书写材料无损检验鉴定提供借鉴。     

对“韬光养晦”的哲学审视

摘要：本文简析了“韬光养晦”外交战略的历史与现实,并结合《孙子兵法》的相关论述,指出中国必须全面审视、理解和坚持“韬光养晦”策略,并要正确认识到“韬光养晦”相较于一种手段更是一种价值。该文认为,破除激进主义的简单思维,破除盛世的迷梦,冷静地正视,有效地反击,运用东方文明的智慧,从而最大限度地突破围堵,为国家的和平发展营造最佳的战略环境,才是当前中国外交战略的根本所在。     

犯罪均值频率——一种犯罪时间分布的测度指标

犯罪在时间分布方面有其特定规律,常规的犯罪总数或平均数等统计量存在不稳定性、偏差性和数据保密性等问题,不利于犯罪时间分布特征的客观对比分析。犯罪均值频率指标克服了传统时间分布统计量存在的问题,可以用来分析犯罪是否偏好发生于特定的时间内,满足了犯罪时间分布规律分析需求。运用该指标对某市5年内的入室盗窃犯罪在星期日别、月份上的时间分布规律进行了实证研究,结果表明,入室盗窃在该市3月份和9-12月份表现为高发期,而在周末则表现为犯罪低谷期。     

Comparative Analysis of the Chemical Profiles of 3,4-Methylenedioxymethamphetamine Based on Comprehensive Two-Dimensional Gas Chromatography-Time-of-Flight Mass Spectrometry (GC × GC-TOFMS)*

Abstract: The chemical profiling of illicit drugs is an important analytical tool to support the work of investigating and law enforcement authorities. In our work, comprehensive two‐dimensional gas chromatography–time‐of‐flight mass spectrometry (GC × GC‐TOFMS) combined with nontargeted, pixel‐based data analysis was adapted for the chemical profiling of 3,4‐methylenedioxymethamphetamine (MDMA). The validity and benefit of this approach was evaluated by analyzing a well‐investigated set of MDMA samples. Samples were prepared according to a harmonized extraction protocol to ensure the comparability of the chemical signatures. The nontargeted approach comprises preprocessing followed by analysis of variances as a fast filter algorithm for selection of a variable subset followed by partial least squares discriminant analysis for reduction to promising marker compounds for discrimination of the samples according to their chemical profile. Forty‐seven potential marker compounds were determined, covering most of the target impurities known from the harmonized one‐dimensional profiling as well as other compounds not previously elucidated.     

故意伤害罪新论

由于我国刑法只规定一个伤害故意,因此,当行为人出于轻伤的故意导致他人重伤结果,应当怎样处罚,不仅在刑法理论中没有一个统一的基准,在司法实践中也是见仁见智。实施暴力行为,导致被害人重伤或死亡的,应当属于故意伤害罪的结果加重形态。在故意伤害的情况下,即便有被害者的承诺,由于作为伤害的社会意义并没有变更,因此,不能阻却构成要件的符合性。但是,基于被害者承诺的违法性的阻却,在某种情况下可以成立。阻却违法性的判断,应当根据被害者处分自己身体的安全这一法益,是否具有社会相当性而进行。针对同时伤害的情况,不应认定为共同伤害。     

Comparison of two methods for isolating DNA from human skeletal remains for STR analysis

Abstract: The quality and efficiency of a standard organic DNA isolation method and a silica‐based method using the QIAGEN Blood Maxi Kit were compared to obtain human DNA and short tandem repeats (STRs) profiles from 39 exhumed bone samples for paternity testing. DNA samples were quantified by real‐time PCR, and STR profiles were obtained using the AmpFlSTR^® Identifiler^® PCR amplification kit. Overall, the silica‐based method recovered less DNA ranging from 0 to 147.7 ng/g (average 7.57 ng/g, median = 1.3 ng/g) than did the organic method ranging from 0 to 605 ng/g (average 44.27 ng/g, median = 5.8 ng/g). Complete profiles (16/16 loci tested) were obtained from 37/39 samples (95%) using the organic method and from 9/39 samples (23%) with the silica‐based method. Compared with a standard organic DNA isolation method, our results indicate that the published silica‐based method does not improve neither the quality nor the quantity of DNA for STR profiling.     

Watch for those fragments of evidence: the use of an automatic timepiece to help correlate a helicopter crash site from the Vietnam War

This case study illustrates the use of the date function on an automatic wristwatch to help identify a Vietnam War helicopter crash site. The location of a crash incident can sometimes be uncertain because of inadequate or inaccurate wartime records and the passage of time. Artifacts recovered from a prospective crash scene are regularly used to correlate the loss incident. In this case study, a recovered automatic watch displayed a date 2 days later than the reported loss incident. Although the date conflicts with the aircraft crash incident report, it is observed that a fully wound automatic watch continues to work for c. 2 days after movement of the watch ceases. Thus, the watch's date in fact correlates with the aircraft crash incident report. It is noted that automatic watches may also be used to date scenes of crime.     

Sex determination from the talus of Koreans by discriminant function analysis

The aims of this study were to investigate the sex discriminating potential of the talus in Koreans and compare this with other analyses in different populations. Statistical analyses were performed using data from nine measurements acquired from 140 tali (70 men, 70 women). The talus of Koreans is dimorphic between sexes in all measurements (p < 0.01). Discriminant function equations were generated by univariate, multivariate, and stepwise methods with a range of accuracy from 67.1 to 87.1%. Stepwise equations of other populations did not discriminate the sex of the Korean sample as accurately as each equation's own accuracies. The variables with high accuracy in this study are useful for sex determination of Koreans on the basis of confirmation of population specificity.