Age, sex and body mass index in relation to calvarial diploe thickness and craniometric data on MRI

It might be critical to determine sex, body mass and age of the individual from skull in forensic medicine and anthropology. Our purpose in this study was to evaluate whether a relationship existed between the diploeic bone thickness measured from glabella, bregma, lambda, opisthocranion, and euryon regions and sex, age and body mass index of the individual. Glabella-opisthocranion, vertex-basion, euryon-euryon, basion-opisthion length were also determined for the same purpose. The anthropological landmarks were determined on sagittal and axial T1-weighted sequences and measurements were obtained on a workstation by two radiologists. A total of 107 subjects (F/M:59/48; mean age: 45.05+/-15.28, age range: 21-81) were included in the study. The mean body mass index was 25.51+/-4.44 [17.50-41]. There was a statistically significant linear correlation between age and diploe thickness from glabella, bregma, lambda, opisthocranion, right and left euryon. There was sexual dimorphism in all craniometric data including the distance between glabella-opisthocranion, vertex-basion, euryon-euryon, basion-opisthion, and calvarial volume. There was a statistically significant linear correlation between body mass index and basion-opisthion length. The diploe thicknesses from certain points of the calvarium are statistically related to each other. A standard cerebral MRI examination would be sufficient to obtain anthropological landmarks and craniometric data. According to this study, it might be possible to identify age, sex and body mass index of the individual from diploeic thickness and craniometric data.     

Analysis of Dopamine D2 Receptor (DRD2) Gene Polymorphisms in Cannabinoid Addicts*

Abstract: The gene encoding the dopamine D2 receptor (DRD2) has been suggested as a candidate gene for substance dependence. In this study, the possible association between Taq1A and Taq1B DRD2 polymorphisms and cannabinoid dependence was investigated. One hundred and twelve cannabinoid addicted and 130 healthy control subjects were included in this study. The Taq1A and Taq1B genotypes were determined in all subjects by polymerase chain reaction. For each polymorphism (A or B), the subjects were categorized into three groups according to their genotype, that is, the subjects with alleles A1/A1, A1/A2, A2/A2; B1/B1, B1/B2, and B2/B2. A significant association was found between Taq1A gene polymorphism and cannabinoid addicts compared to the control subjects. This finding suggests that polymorphism of the Taq1A, but not the Taq1B, may be associated with the susceptibility to cannabinoid dependence. Further clinical studies are required to be carried out for confirmation and evaluation of these findings.     

A serious medicolegal problem after surgery: gossypiboma

After surgery, the most common foreign bodies retained in the abdominal cavity are the surgical sponges. The aim of the present study was to emphasize the importance of gossypiboma, which is a serious and medicolegal problem. The records of 12 patients with a confirmed diagnosis of gossypiboma after abdominal surgery at Dicle University Hospital were retrospectively reviewed between January 1994 and December 2009. Eight of the 12 patients were females, and 4 were males. Previously, 7 patients had been operated on electively, and 5 had undergone operations on an emergency basis. Abdominal ultrasonography clearly demonstrated gossypibomas in 5 patients, and computed tomography demonstrated a more precise image of retained surgical sponges in 3 patients. One patient died because of ventricular fibrillation; the other 11 patients were discharged in good health. To eliminate the risk of gossypibomas, all sponges should be counted at least twice (once preoperatively and once postoperatively); use of small sponges should be avoided during laparotomy, and only sponges with radiopaque markers should be used. The surgeon should explore the abdomen before closure. In cases in which the sponge count is uncertain, an abdominal x-ray should be performed before closure.