Genetic discrimination: Huntington's disease and the Americans with Disabilities Act

This Note discusses the potential for genetic discrimination, current views as to whether genetic conditions will be covered by the Americans with Disabilities Act ("ADA"), and the specific issue of whether presymptomatic persons who test positive for Huntington's disease should be classified as persons with a "disability" within the meaning of the ADA. In considering whether presymptomatic Huntington's individuals have a disability under the ADA, an analogy is made between Huntington's disease and HIV-positive status. Inter alia, Huntington's disease and HIV-positive status are analogous in that, at the time of diagnosis, victims of both diseases may have no symptoms and may remain healthy for a number of years; but even though the exact time of onset of both diseases is unascertainable, death of both victims within a given range of years is highly likely. Further, both Huntington's disease and HIV are transmitted to offspring at a relatively high rate. Given these similarities, the author argues that Huntington's individuals should be afforded the protections of the ADA for the same reasons that HIV-positive persons are protected.     

STR Data for the AmpFlSTR Identifiler loci in three ethnic groups (Malay, Chinese, Indian) of the Malaysian population

Allele frequencies for the 15 STR loci in the AmpFlSTR Identifiler kit were determined and compared for the three main ethnic groups of the Malaysian population comprising 210 Malays, 219 Chinese and 209 Indians. Blood was placed on FTA paper and DNA was purified in-situ.     

The transnational protection regime and democratic breakthrough in Taiwan and South Korea

External state pressure is understood to have played a causally significant role in democratic breakthrough in Taiwan and South Korea during the 1980s. This article problematizes the international dimensions of democratization in Taiwan and South Korea by first providing a revisionist account of external agency which involved complex networks of transnational nonstate and substate actors. These included human rights activists, Christian churches and related ecumenical organizations, members of the Taiwanese and Korean diaspora communities in the US, academics and students, foreign journalists, and members of the US Congress. In forming a transnational “protection regime” during the 1970s and 1980s to protect the political opposition from repressive governments, they contributed to the development of effective democratic movements. The case studies provide us with a more comprehensive view of the international dimensions of democratization, speaking to both the country specific and general theoretical literatures on democratization at the same time.     

Un-Packing Packaged Cultures: Chinese-ness in International Business

This paper focuses on how the Chinese are represented in the international business literature. Chinese cultures are packaged to make knowledge about the Middle Kingdom more accessible to a general audience. The ways in which these packaged cultures are framed and constructed will be questioned here. Drawing inspiration from Foucault, this article identifies four traits of a packaged culture – it mediates, it asserts the uniqueness of the culture, it selectively packages the culture and it claims that cultural differences matter in business. These traits will form the basis for comparing and examining three methods of packaging a culture, namely the general-macroscopic, ethnographic present and critical emergence approaches. This paper concludes that researchers should reflect on the power they yield when they represent another culture, and that the general public may privilege theories that are accessible rather than sound.

Beyond the Rails

The inauguration of the railway be-tween China and Laos is a key milestone in the realization of the Pan-Asian Railway Network running between Kunming, capital of Yunnan Province in southwest China, and Singapore.     

NEW DIMENSIONS

The active involvement of China in UN peacekeeping operations in the past three decades has earned it the status of global peace provider. Ever since China first deployed troops to the UN's blue helmets in 1990, when it sent five military observers to the Middle East, its commitment to serving the wellbeing of humanity through UN peacekeeping remains a key initiative showcasing the country's soft power.     

RCEP: Building Bridges,Not Walls

The parliamentary ratification of the Regional Comprehensive Economic Partnership (RCEP) agreement by 10 signatory states has finally set the world's biggest ever free trade bloc into motion, albeit only among the ratifying na-tions, on January 1, 2022. Six Association of Southeast Asian Nations (ASEAN) member states, namely Brunei, Cambodia, Laos, Singapore, Thailand and Viet Nam, as well as Australia, China, Japan and New Zealand, have completed the ratification procedures. The RCEP was also signed by another four ASEAN members, namely Indonesia, Malaysia, Myanmar and the Philippines, as well as the Republic of Korea (ROK). Once in full effect, it will cover approximately 30 percent of the world's population and one third of global GDP. The agreement manifests the firm commitment of all 15 signatory economies in the Asia-Pacific region to upholding an open, inclusive and rules-based multilateral trading system. Its implementation is particularly timely for the region as its economies struggle to recover from the impacts of COVID-19 and rising trends of de-globalization.     

Haplotype diversity of 16 Y-chromosomal STRs in three main ethnic populations (Malays, Chinese and Indians) in Malaysia

We have analyzed 16 Y-STR loci (DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385a/b, DYS393, DYS391, DYS439, DYS635 or Y-GATA C4, DYS392, Y-GATA H4, DYS437, DYS438 and DYS448) from the non-recombining region of the human Y-chromosome in 980 male individuals from three main ethnic populations in Malaysia (Malay, Chinese, Indian) using the AmpFlSTR((R)) Y-filertrade mark (Applied Biosystems, Foster City, CA). The observed 17-loci haplotypes and the individual allele frequencies for each locus were estimated, whilst the locus diversity, haplotype diversity and discrimination capacity were calculated in the three ethnic populations. Analysis of molecular variance indicated that 88.7% of the haplotypic variation is found within population and 11.3% is between populations (fixation index F(ST)=0.113, p=0.000). This study has revealed Y-chromosomes with null alleles at several Y-loci, namely DYS458, DYS392, DYS389I, DYS389II, DYS439, DYS448 and Y-GATA H4; and several occurrences of duplications at the highly polymorphic DYS385 loci. Some of these deleted loci were in regions of the Y(q) arm that have been implicated in the occurrence of male infertility.