Determination of MDMA, MDA, MDEA and MBDB in oral fluid using high performance liquid chromatography with native fluorescence detection

This paper describes the analytical methodology for the determination of MDMA, MDA, MDEA and MBDB in oral fluid. After a liquid–liquid extraction, the analysis was carried out by high performance liquid chromatography (HPLC), with fluorescence detection. The detector wavelength was fixed at 285 nm for excitation and 320 nm for emission. The mobile phase, a mixture of phosphate buffer (pH = 5) and acetonitrile (75:25), and the column, Kromasil 100 C8 5 μm 250 mm × 4.6 mm, allowed good separation of the compounds in an isocratic mode in only 10 min. The method was validated and showed good limits of detection (2 ng/mL) and quantitation (10 ng/mL) for all the amphetamine derivatives. No interfering substances were detected. A stability study of these compounds in oral fluid stored at three different temperatures (−18, 4 and 20 °C) over 10 weeks was conducted, showing a time-dependent degradation of the four compounds.     

The Lost Sexenio: Vicente Fox and the New Politics of Economic Reform in Mexico

The 2000 presidential election of opposition candidate Vicente Fox signaled an end to seven decades of Mexico's single-party regime and seemed to herald the advent of truly competitive politics. But by 2003, economic reform had largely stalled, and Fox's party suffered a historically unprecedented midterm' loss in the congress. This article analyzes the underpinnings of policy gridlock in the Fox administration. Fox inherited the need for microeconomic restructuring and increased competitiveness, more innovative and pragmatic state policies, the need to pay attention to the country's sharp income inequalities, and the challenge of crafting a political strategy that could build a middle ground and foster policy consensus. With his party's minority standing in the congress, Fox was constrained from the start by divided government. But more effective statecraft and coalition building would have helped. These will be essential elements for the success of any post-Fox regime.     

A New Scramble for African Oil? Historical, Political, and Business Perspectives

It has been suggested that Africa is experiencing a ‘NewScramble’ thanks primarily to its oil and gas wealth,with the United States and the People’s Republic of Chinaactively competing for access to Africa’s resources. Thisarticle aims to scrutinize the claim that Africa is facing aNew Scramble, analysing the nature of the economic and politicalchanges at work, the importance of Africa’s oil, and thepolitical and economic forces behind the new oil rush. The articlestarts with an overview of the phenomenon labelled by some asthe ‘New Scramble’. The main body of the articleevaluates the existence of a New Scramble from three subjectperspectives: history, international relations, and businessstudies. Finally, by analysing the likely impact on the economiesof oil-producing states, it considers whether we should dismayor rejoice over the ‘New Scramble for Africa’. Itconcludes that the existence of a New Scramble or a US–Chineserace for Africa should be treated with some caution and thatthe use of terms such as ‘scramble’ and ‘race’is perhaps misleading, while the economic impact of oil investmentsis likely to be bleak.     

Correction to: The Public Power of Judgement: Reasonableness Versus Rationality—Setting the Ball Rolling

International Journal for the Semiotics of Law - Revue internationale de Sémiotique juridique - In the original publication of the article, the paragraph beginning “We begin with two...     

What is the Theory Legal Argumentation For?

The paper aims to present the legal theories of legal argumentation constructed in the last century, organised into two groups: the precursors (Viehweg, Perelman and Toulmin) and the authors of the standard theory (MacCormick and Alexy). Then, some criticisms about all these conceptions are presented. And finally, an outline of a theory of legal argumentation is made, capable of overcoming some of the previous criticisms. The fundamental idea for this is to build a very abstract concept of argumentation that could then allow various interpretations or conceptions of legal argumentation. From here, one would be in a position to find an answer to the three main argumentative questions raised by legal practice: how to analyse an argument, how to evaluate it, how to argue.