The generic drug market in Japan: will it finally take off?

Historically, brand-name pharmaceuticals have enjoyed long periods of market exclusivity in Japan, given the limited use of generics after patent expiration. To improve the efficiency of the health-care system, however, the government has recently implemented various policies aimed at increasing generic substitution. Although this has created expectations that the Japanese generic drug market may finally take off, to date, generic usage has increased only modestly. After reviewing the incentives of key market participants to choose generics, we argue that previous government policies did not provide proper incentives for pharmacies to boost generic substitution. We offer some recommendations that may help to increase generic usage.     

The collaboration of ‘ghostwriting’ and literature – the case of Kawabata Yasunari

Abstract: Kawabata Yasunari is Japan's first Nobel Prize recipient for literature and thus an emblem of the modern Japanese writer, but as this essay demonstrates, this writer's career, like that of so many throughout Japan's premodern and modern history, is spanned by the curious practice of ghostwriting. Taking up the specific case of Kawabata, the article exposes a wider conflict between the modern West's notion of the original artist, underwritten by its idea of individualized creativity, and modern Japan's persistent adherence to ghostwriting's more collaborative premodern concept of creativity. Subjecting fine-grained literary historical analysis to its far-reaching theoretical consequences for the modernness of modern literature, Japanese and otherwise, this essay shows how the spectre of Kawabata's ghostwriting haunts our contemporary, and therefore possibly anachronistic, understanding of ‘modern’ literary practice.     

New Conventions Required: Ideas to Re-invigorate Japanese Party Politics

Over the past 20 years, Japanese politics has changed significantly. There have been many improvements over the old LDP politics. At the same time, however, the rules of the game, which were predicated on the dominance of a single political party and on factional politics, have inevitably changed, and, in accordance with this situation, the conventions that prescribed the party-political order have fallen by the wayside. Given this situation, new conventions are now required that will make Japanese politics function. This article will discuss the most pressing topics: they are the appointment of the prime minister, the political cycle, bicameralism and party politics, intra-party governance, and the relationship between ministers and bureaucrats. These rules will not derive from new laws or institutions, but will be based on new conventions agreed to by the political parties. Political parties are to be the key actors in creating the new conventions, which should provide the rules of the game for Japanese politics.     

东亚世界的形成与中国皇权——以六朝时期为重点

中国的汉与六朝时期,日本和朝鲜都开始接受汉字、儒教、礼制,与中国一道构成了东亚世界.一方面,中国皇帝为巩固国内统治,需要利用周边民族的朝贡来提高自身权威;另一方面,由于倭国在从分裂走向统一及统一后不断与朝鲜半岛政权合纵连横的纷争中,为使自己处于优势位置,也有必要利用中国皇帝的权威.正是在这种利益关联的互动中,形成了以中国为中心的古代东亚的国际关系.此外,周边诸国为了提高自身的国际地位,也接受了中国的价值观,特别是基于礼的文化.     

Autopsy report on central pontine myelinolysis triggered by vomiting associated with digoxin intoxication

An 87-year-old male, prescribed digoxin and furosemide for congestive heart failure and Alzheimer disease, had dehydration and anemia due to poor food intake and hemorrhagic cystitis. Repeated vomiting due to an upper respiratory infection caused disturbance of consciousness and hypotension. The patient was admitted to hospital and diagnosed with digoxin intoxication and hypernatremia. The serum sodium (Na⁺) level was corrected, but the patient died 4 days after admission following uncontrollable seizure. A histologic examination after an autopsy revealed characteristic findings of central pontine myelinolysis (CPM). This is the first autopsy report on CPM triggered by vomiting in association with digoxin administration.