Detection of furadan in biological fluids

Optimal conditions have been determined for furadan isolation from biological fluids by means of the mixture of solvents ethyl acetate-acetone in volume 1:1. Possible purification of the compound from coextractive substances of biomaterial on the column with silica gel L 100/160 mcm is demonstrated. IR-spectrophotometric methods and high performace liquid chromatography with a detector of photodiode matrix are proposed for identification and quantitation of furadan in blood and urine specimens.     

Occupational safety and health of factory workers in European countries in the nineteenth century: historical and legal analysis

ABSTRACT

Historical and legal analysis of factory workers’ occupational safety and health in Europe in the nineteenth century has been carried out. In particular, the main causes of industrial injury and occupational diseases among factory workers of those times were analyzed and classified. The main negative consequences of child labor in factories are determined. The distribution of industrial injury and occupational diseases by age group is shown. The influence of labor conditions at the factories on the health of the descendants of factory workers of those times was analyzed. The features of the organization of control over compliance with the safety requirements of workers’ health are highlighted. The issues of introduction of legal regulation of factory workers’ safety and health, as well as child labor regulation (i.e. working hours limits and working conditions regulation) in factories, are analyzed. The issues of implementation of legislation that established compensations for factory workers in the event of industrial injury and occupational diseases of those times are analyzed.     

Current approaches to analysis of narcotic drugs in biological substances

A method of analysis of basic narcotic drugs in urine is described. It consists in isolation by solid phase extraction, derivation and identification by gas chromatography with mass-selective detector. The approaches applied in the above method can be used for analysis of narcotic drugs undetectable by preliminary investigations as well as for urine examination for pharmacological or other biologically active substances.     

The analysis of the methylenedioxy derivatives of amphetamine]

Methods for analysis of narcotics belonging to amphetamine methylene dioxy derivatives (MDD) are reviewed. The characteristics of these agents, their metabolism, and methods used for their detection and identification (TLC, GC, HPLC, GC/MS) are described. Methods for their extraction from biological objects (human urine and hair) are described. Efficacy of MDMA and MDEA from the urine by different extractants is assessed. The data demonstrate different potentialities for detection and identification of amphetamine MDD, including those in biological specimens (human urine and hairs), by numerous chromatographic methods.