Chronic hydrocephalus and alcohol abuse in a young male suicide

The paper describes a case of suicide in a young man affected by compensated chronic hydrocephalus who was subject to alcohol abuse. The case was studied by means of a complex set of analyses, including circumstantial and clinical data, anatomohistopathological findings, and chemicotoxicologic tests. What clearly emerges in the case is the importance of a continuing neuropsychological follow-up in patients with shunted hydrocephalus. The forensic interest in the case is due to the peculiar autopsy findings discussed in relation to the possible causes of sudden death in subjects with hydrocephalus.     

Controlling Immigrants: The Latent Function of Italian Administrative Orders

Enforcement of new—or relatively new—administrative powers targeting control and criminalization of behaviorbehavior has become increasingly common in Italian cities in recent years. Defined as ordinanze sindacali, Mayors’ Administrative Orders (MAOs) have traditionally been among the powers available to mayors to regulate urban life. Under a new national law passed in 2008, their use in controlling undesirable behavior ranging from minor social and physical incivilities to prostitution and social problems like begging and vagrancy has become increasingly common. In this paper, using data from our own research and from national and local studies, we discuss these orders from a new perspective, showing how they have been used in Italy to criminalize statuses and behaviors of a specific vulnerable social group: namely, legal and illegal immigrants. We describe the main features of these administrative tools, their complex interactions with the criminal justice system and immigration laws, and the mechanisms through which they target irregular and regular immigrants and their use of public space. We contextualize their enforcement in Italian cities in the broader development of exclusionary policies against immigrants and in the more general tendency to increase criminalization of groups and behaviors that seem to be part of a common punitive turn in many Western countries.     

Disenchanted Presents,Haunted Pasts,and Dystopian Futures: deferred millennialism in the cinema of Meng Jinghui

Meng Jinghui's Chicken Poets (2002) presents a postmodern meditation on the state and fate of Chinese cultural production, intellectual discourse, and social relations at the turn of the century and the millennium. Albeit released two years after 2000, it retains symptomatic traits of the fin-de-siècle and millennial mentality and is therefore examined as an instance of ‘deferred’ or ‘residual’ millennialism. As typical of such narratives, it merges visions of hope and horror, dream and disaster. The film is founded on a dialogic intersection of multiple ‘time–spaces’ of signification, each providing a separate locus of reflection and critique. Besides disclosing distinct discursive targets, the structural interplay of these different chronotopes also establishes generic distinctions within the narrative. Chicken Poets relates to the present as a self-reflexive Künstlerfilm addressing the conflict of creation and commodity in times of mechanical reproduction and mediated stardom. Its enquiry into the past triggers ghostly resurrections and nostalgic visions of compensation and resistance. Its imagination of the future generates apocalyptic fantasies of disaster while disclosing prospects of redemption.     

Rapid analysis of caffeine in "smart drugs" and "energy drinks" by microemulsion electrokinetic chromatography (MEEKC)

A novel method based on microemulsion electrokinetic chromatography (MEEKC) with diode array detection (DAD) for rapid determination of caffeine in commercial and clandestine stimulants, known as "energy drinks" and "smart drugs", is described. Separations were carried out in 50 cm × 50 μm (ID) uncoated fused silica capillaries. The optimized buffer electrolyte was composed of 8.85 mM sodium tetraborate pH 9.5, SDS 3.3% (w/v), n-hexane 1.5% (v/v) and 1-butanol 6.6% (v/v). Separations were performed at a voltage of 20 kV. Sample injection conditions were 0.5 psi, 3 s. Diprofilline was used as internal standard. The determination of the analytes was based on the UV signal recorded at 275 nm, corresponding to the maximum wavelength of absorbance of caffeine, whereas peak identification and purity check was performed on the basis of the acquisition of UV radiation between 200 and 400 nm wavelengths. Under the described conditions, the separation of the compounds was achieved in 6 min without any interference from the matrix. Linearity was assessed within a caffeine concentration range from 5 to 100 μg/mL. The intra-day and inter-day precision values were below 0.37% for migration times and below 9.86% for peak areas. The present MEEKC method was successfully applied to the direct determination of caffeine in smart drugs and energy drinks.     

“Tampering to Death”: A Fatal Codeine Intoxication Due to a Homemade Purification of a Medical Formulation

Many homemade tamper processes of medical codeine formulations are available on selected “forums” on the Internet, where recreational codeine users claim to be able to purify codeine by removing additives, such as acetaminophen, to avoid or limit adverse effects. In this work, it is reported and discussed a fatal case of codeine intoxication. The findings of objects such as jars, filters, and tablets, and amounts of unknown liquid material at the death scene investigation suggested a fatal codeine intoxication after the tampering procedure called “cold water extraction.” Toxicological results obtained from the analysis of both the nonbiological material and the body fluids of the decedent integrated with the information collected at the death scene investigation confirmed the above‐mentioned hypothesis. This report underlines the importance of a tight interconnection between criminalistics and legal medicine to strengthen the identification of the cause of death and the reconstruction of the event.     

Carbohydrate-deficient transferrin (CDT): A reliable indicator of the risk of driving under the influence of alcohol when determined by capillary electrophoresis

Carbohydrate-deficient transferrin (CDT) is a marker of chronic alcohol abuse, which has recently been introduced to evaluate the physical fitness for obtaining a driving license. The aim of the present study was to evaluate the prevalence of elevated CDT levels in subjects stopped while driving under the influence of alcohol by using a validated method based on capillary electrophoresis. The study was carried out on a group of 40 drunken drivers (group A) and on a control group (n = 51) of subjects chosen from the general population (group B). CDT was directly determined by capillary electrophoresis in free solution and UV detection at 200 nm. CDT results from both groups were classified as “negative” or “positive” on the basis of the cut-off set at 2.00% (CDT index). The subjects classified as “positive” in group A were 24 (60%), whereas in group B were 2. The subjects classified as “negative” in group A were 16 (40%), whereas in group B was 49 (96.1%). The comparison of the observed percentages, evaluated with the χ²-test, was highly significant (p < 0.001). The present study confirms the high prevalence of chronic alcohol abusers among drunken drivers and the usefulness of CDT as a predictor of the risk of drunk driving.