肺气肿肺气虚证大鼠血气分析、血中细胞因子及肺组织病理学的改变

目的 :探索肺气虚证的本质。方法 :将 6 0只大鼠随机分为模型组与对照组 ,复制肺气肿肺气虚证模型 ,分别检测 pH、氧分压 (pO2 )、氧饱和度 (SaO2 % )、二氧化碳分压 (pCO2 )、白细胞介素 6 (IL 6 )、白细胞介素 8(IL 8)、肿瘤坏死因子 α(TNF α)及肺组织病理学的改变。结果 :模型组pH、pO2 、SaO2 %下降 ,pCO2 升高 ,与对照组比较 ,差异有显著性 (P <0 .0 1 ) ;模型组IL 6、IL 8、TNF α升高 ,与对照组比较 ,差异有显著性 (P <0 .0 1 ) ;病理组织学及超微结构检查显示肺组织有慢性支气管炎及肺气肿病变。结论 :肺气肿肺气虚证大鼠存在低氧血症和高碳酸血症 ,血中细胞因子IL 6、IL 8、TNF α升高 ,可能是肺气虚证从轻度向中、重度发展的重要原因之一。     

Acute myoglobinuria as a fatal complication of heroin addiction

A fatal case of myoglobinuria complicating heroin addiction is described. Clinically the patient had no overt symptoms of rhabdomyolysis. Pathologists should be alerted to this rare complication in heroin addicts who die of no apparent cause. The antimyoglobin immunoperoxidase technique is useful in confirming the diagnosis.     

Restriction fragment length polymorphism analysis of forensic science casework in the People's Republic of China.

Restriction fragment length polymorphism (RFLP) analysis for the purpose of individualization is now being used in casework in the People's Republic of China. This report describes the use of the multilocus minisatellite probe 33.15 to solve three cases, including two homicides and a rape. In the third case, fetal tissue was analyzed to prove that the alleged rapist was, in fact, the father. In each case, analysis of deoxyribonucleic acid (DNA) resulted in a positive match. The probability of chance association of the DNA fingerprint was calculated as 5.6 x 10(-12), which is similar to the figures reported in the literature.     

海口市交通状况与交通拥挤的研究

通过分析海口市的路网结构和交通流的特性,提出了交通拥挤评价的标准,根据评价的结论对海口市的路网提出改善措施,并介绍了重点路口的改善对策。     

英国的调解制度--近期发展

本文分析了英国近来的一些案例,介绍了英国在采取非诉方法解决争议方面的最新发展,强调了法院在一些案件中的态度.     

Quantitative analysis of chlorpromazine by electron spin resonance (ESR) spectroscopy

A simple and sensitive method is described for quantitative analysis of chlorpromazine in blood, serum, urine and tissue homogenate. The chlorpromazine cation radical produced by adding perchloric acid and 2,3-dichloro-5,6-dicyano-p-benzoquinone to the sample can be detected by the ESR method at room temperature. The sensitivity limit is 10 ng, that is, 20 μl of the solution containing 0.5 μg chlorpromazine/ml. The time needed for the measurement is within 10 min. The chlorpromazine radical thus produced is very stable; for example, 95% of the radical was observed after 24 h. The advantage of this method is discussed by comparing with the ordinary spectrophotometry which requires the purification of the sample.     

Acidic and neutral drugs screen in blood with quantitation using microbore high-performance liquid chromatography–diode array detection and capillary gas chromatography–flame ionization detection

Blood previously acidified with aqueous saturated ammonium chloride solution was extracted with ethyl acetate. The dried extract was subjected to acetonitrile–hexane partition. The acetonitrile portion was analysed for the presence of acidic and neutral drugs by HPLC–DAD (200 mm×2.1 mm I.D. microbore ODS-Hypersil column) and GC–FID (25 m narrow-bore×0.25 mm I.D. HP-5 column with 0.33 μm film thickness). The protocol was found to be suitable for both clinical toxicology (including emergency toxicology) and postmortem toxicology. At least 66 drugs of interest were unequivocally identified by RRTs (HPLC) and UV spectra (DAD) match while another 12 were unequivocally identified by double RRTs match (HPLC and GC). Quantitation was facilitated by incorporating calibration blood standards in each assay batch. The five drugs most commonly encountered in clinical blood specimens (1150 cases) were: paracetamol (47.4% of the cases); chlormezanone (6.6%), theophylline (1.74%), naproxen (1.65%) and mefenamic acid (1.56%). The following drugs were detected in toxicologically significant quantities in postmortem blood specimens (245 cases): phenobarbitone (1.22% of the cases), naproxen (0.82%), chlormezanone (0.82%), theophylline (0.82%), carbamazepine (0.41%) and paracetamol (0.41%).     

浅析庄子的"物化"思想

庄子认为,作为自然的存在者,人一出生就在现实的囚笼中挣扎,人类超越这一困境的坦途,即“物化”。“物化”的本质也就是人与物、人与道这两个层次之间的互动关系,通过这种互动,达到“心斋”和“坐忘”,只有这样才能摆脱工具理性的桎梏。     

伊犁河谷生态畜牧业及现代化产业化发展对策研究

畜牧业是伊犁河谷最具特色的传统产业和基础产业,大力发展生态畜牧业及现代化、产业化是河谷农业现代化的重要途径.但目前伊犁河谷发展生态畜牧业及现代化、产业化的基本制约因素凸现,为此,应从加快政府对生态畜牧业及现代化产业化的政策引导、坚持"以草立业"、扶持壮大引进畜产品加工龙头企业完善产品链条、充分发挥科技的作用、大力增加投入等方面入手,推进伊犁河谷生态畜牧业及现代化、产业化发展.