STR analysis of artificially degraded DNA-results of a collaborative European exercise

Degradation of human DNA extracted from forensic stains is, in most cases, the result of a natural process due to the exposure of the stain samples to the environment. Experiences with degraded DNA from casework samples show that every sample may exhibit different properties in this respect, and that it is difficult to systematically assess the performance of routinely used typing systems for the analysis of degraded DNA samples. Using a batch of artificially degraded DNA with an average fragment size of approx. 200 bp a collaborative exercise was carried out among 38 forensic laboratories from 17 European countries. The results were assessed according to correct allele detection, peak height and balance as well as the occurrence of artefacts. A number of common problems were identified based on these results such as strong peak imbalance in heterozygous genotypes for the larger short tandem repeat (STR) fragments after increased PCR cycle numbers, artefact signals and allelic drop-out. Based on the observations, strategies are discussed to overcome these problems. The strategies include careful balancing of the amount of template DNA and the PCR cycle numbers, the reaction volume and the amount of Taq polymerase. Furthermore, a careful evaluation of the results of the fragment analysis and of automated allele calling is necessary to identify the correct alleles and avoid artefacts.     

Strategische Umweltprüfung für die Offshore-Windenergienutzung – Großräumige Wirkungen und Monitoring – Tagung an der Universität Lüneburg, Professur für Öffentliches Recht, 20.4.2006

Ohne Zusammenfassung     

Antitrust Enforcement: Abuse Control or Notification?

The European Union is currently revising its system of centralised authorisation for agreements between firms falling within the scope of Article 81 (1) of the EC Treaty but qualifying for exemption from the general prohibition. The proposed reform in the 1999 White Paper on Modernisation of the Rules Implementing Articles 81 and 82 of the EC Treaty involves the abolition of the notification and exemption system and its replacement by a directly applicable exception system where restrictive practices qualifying for exemption are lawful per se and subject to abuse control. This paper compares both the current notification system and the proposed system of ex-post control in a game-theoretical framework. If precommitment to an enforcement probability by the antitrust authority is not possible and a mixed equilibrium exists for both systems, the notification system is superior to the system of abuse control in terms of social welfare.     

How to benefit from publicly funded pre-competitive research: an empirical investigation for Germany’s ICR program

This paper contributes to the debate on the systemic effects of technology policy by investigating spillovers of pre-competitive publicly funded Industrial Collective Research (ICR) in Germany which is carried out by non-profit research institutes. Using data for 911 firms surveyed in 2006, the results show that non-actively involved firms in ICR projects use ICR results to a large extent. Almost all of these firms are engaged in collaborative research projects with non-profit research institutes. We conclude that company–scientists linkages are an important pre-requisite to absorb ICR results by non-actively involved firms in ICR projects.     

Functions of mass media in interpersonal communication

SUMMARY

This paper is the result of a research project on the function(s) of mass media in interpersonal conversation. Based on their research findings the authors conclude that mass media and mass media topics play an important role in conversation; that it forms an integrated component of personal communication; that the mass media is particularly often mentioned in small groups and in groups of lower intensity of conversation, and that the mentioning of the mass media as such fulfills several functions in conversation.     

Changes in the handling of corruption scandals in Japan since 1994

Over the last fifty years, the Japanese political landscape has been shaken from time to time by the exposure of corruption scandals. In 1993, a multiparty coalition won government in Japan and initiated a package of reform legislation that was passed by the Diet in 1994. The system of legal controls was tightened, penalties for wrongdoing were increased, and the flow of money in politics was made more transparent. However, after more than five years of debate about reform and putting an end to money politics, corruption is still prominent in Japanese politics, and the number of corruption scandals even seems to be growing. Dr. Verena Blechinger of the German Institute for Japanese Studies analyzes how corruption scandals were handled up till 1993, and how this has changed since. She argues that the process of political reform since 1994 has brought about change in the structural framework of the Japanese political system which has caused a shift in relations between the three main political elite groups.     

Introduction: Dimensions of Sino–Japanese rivalry in a global context

Abstract

This special issue analyzes the evolving notion of Sino–Japanese rivalry and its effects on concrete foreign policy measures of both states in a global context. China’s emergence as a great power and Japan’s attempts to ‘normalize’ its foreign relations took place alongside both countries increasing their political engagement in world regions beyond Northeast Asia. As a result, there has been increasing mutual monitoring of and increasing concern expressed about the intentions and actions of the respective other on these different levels of world politics. This has largely been neglected in the literature. This special issue closes the gap in the literature by providing answers to the following questions: Is there a Sino–Japanese rivalry in the first place? Which factors define this rivalry? Are there different levels and/or kinds of rivalry? Which factors influence Sino–Japanese rivalry in different regions and on different levels of the international system? Do these factors differ across regional and institutional boundaries? Answering these questions requires us to conceptualize what is meant by rivalry as well as to focus on Sino–Japanese interaction in different world regions and on the level of international institution building. This special issue also contributes to the literature on interstate rivalry by challenging common understandings of the concept of rivalry and by adding new facets and interpretation of rivalry based on the concrete empirical cases. It will therefore provide a broadened perspective on the characteristics of Sino–Japanese relations, the mutual impacts of Japan’s and China’s globalizing foreign policies, and on our understanding of the determinants and mechanisms of interstate rivalries.     

From Form to Function to Sustainable Solutions? Reforming Public Sectors in Low Income Countries: New Approaches and Available Evidence of “What Works”

The article reviews the evidence about success of public sector reforms in low and middle income countries, external support for such reforms, and recent ideas of how such support could be better designed and implemented. Enthusiasm for supporting public sector reforms has decreased over the past decade, and available data suggest that there has been little overall improvement. However, it also indicates that a small number of countries have significantly strengthened their public sectors over the past 10 to 20 years. The article then reviews five new approaches that have been proposed for better supporting public sector reforms. It looks at how they diagnose what has not worked and the implications of what should be carried out differently. Furthermore, it explores to what extent the available evidence of overall stagnation as well as of success cases fits with these proposed alternatives, to gauge to what extent they are likely to make a difference. The final section sets out the implications. Development agencies should seek to deliberately test a combination of the proposed alternative approaches, particularly in more difficult contexts, taking political feasibility as a basis and adding other elements. The urgency to make progress remains high. Copyright © 2016 John Wiley & Sons, Ltd.