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A fatality following ingestion of the drug baclofen (Lioresal) is described. Baclofen was identified in urine by gas chromatography/mass spectrometry. After derivatization with trinitrobenzene sulfonic acid, baclofen was quantitated in serum and urine by high-performance liquid chromatography. The concentration of baclofen was 17 mg/L in serum and 760 mg/L in urine collected approximately 12 h after the overdose. To our knowledge, this is only the second reported fatality involving a baclofen overdose. The previous case did not include quantitation of baclofen in any biological fluid.  相似文献   
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Charles Taylor's engagement with Marx and the Marxist tradition has been relatively neglected in the literature on his work. This is a strange omission, because he was not only a pivotal figure in the development of the New Left, but also wrote many pieces which critically engaged with the main principles of Marx and Marxism. This paper re-examines Taylor's engagement with Marxism and thereby exposes a neglected element in his political philosophy. The following themes emerge: the self; Taylor's conception of the affirmation of ordinary life; democracy; ecology; and religion. In one area at least, the affirmation of ordinary life, a crucial element of Marxism is retained and positively endorsed by Taylor. In relation to the other themes, while he raises important issues for Marxist theory, he is, at times, far too quick to dismiss Marx's arguments and also misses similarities between those arguments and his own work.  相似文献   
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The social welfare effects of legislatures in presidential systems, such as the U.S. Congress, are frequently lamented. In response, there are proposals to reform the separation of powers system by giving presidents control of the legislative agenda and weakening rules such as the filibuster. We provide a game-theoretic analysis of the policy and social welfare consequences of a more executive-centric system. Integrating standard assumptions about legislative and executive incentives into a dynamic model of decision making with private investment, we show there are a variety of conditions under which stronger executives do not produce better outcomes. Moreover, we characterize how these conditions depend on factors such as the stability of the policymaking environment or investment fundamentals. Our findings are robust and consistent with empirical observations that U.S. policy outputs are not necessarily worse than those of nations with stronger executives, which more closely approximate prominent proposals by populist-oriented reformers.  相似文献   
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Larmer  Miles; Fraser  Alastair 《African affairs》2007,106(425):611-637
Zambia's 2006 election was won by incumbent President Levy Mwanawasaand his Movement for Multi-Party Democracy (MMD). However, itis argued here that the most important outcome of the campaignwas the successful articulation of a new populist politics byMichael Sata's Patriotic Front (PF), which won a significantmajority in urban areas. Sata's attacks on foreign investors(particularly from China) for their abuse of the workforce andtheir supposedly corrupt relationship with the MMD resonatedwith urban Zambians, already angered by the negative impactof economic liberalization. PF's campaign injected popular socialdemands into what had become a moribund political debate. TheMMD government is now adopting PF policies in an attempt torestore its own urban support base. The article describes thecampaign and its outcomes, contrasting the political discourseof the MMD and PF and analysing the differences in voting behaviourbetween rural and urban Zambians. It argues that recent reliefof 92 percent of Zambia's international debt, along with therenewed profitability of the copper mining industry, have createdconditions for the re-emergence of a nationalist-developmentalpolitical framework.  相似文献   
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This article seeks to interrogate the category of the ‘political’ through an exploration of the present trajectory of feminist peace activism in Sri Lanka. It provides a critical appraisal of current strategies adopted by the majority of feminist organizations that seem to suggest a shift from ‘refusal’ to ‘request’. This results in the resort to more ‘feel safe’ campaigns, rather than the placement of oneself in an antagonistic and oppositional relationship with the state, which continuously calls the political into question. It concludes by considering two other kinds of political trajectories and the disparate conceptual challenges each offers.  相似文献   
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