A method using two dimensions of the patent classification for measuring the technological proximity: an application in identifying a potential R&D partner in biotechnology

This paper aims to show how the information contained in patent documents can be used to identify basic and specific technological proximities between firms and therefore a potential research and development (R&D) partner. More generally, it looks at patents as a strategic tool that can be used for concluding cooperative R&D agreements (CRDA). The approach begins by looking at the state of the art on the role of technological proximity in CRDAs. This review clearly raises the problem of measuring technological proximity, which needs to be gauged at a two-fold level: general and specific. Then a dual method based on patent portfolios for analyzing the profiles of different potential partners is described along with an example of its application. Concretely, the exploratory study proposed here is based on an analysis of the patent portfolios of 14 French listed biotechnology companies and those of their main R&D partners. The analysis of 5,603 patents filed by the focal firms and their partners shows how the approach can be used to identify compatible partners that are more or less technologically matched.     

False homozygosities at various loci revealed by discrepancies between commercial kits: implications for genetic databases

Routine control of 2055 consecutive genotypes revealed discrepancies between the profiles established with the SGM plus and/or Profiler plus kits on one hand, and the profiles established with the Powerplex16 kit on the other hand. Furthermore, five discrepancies for vWA, three for D8S1179, two for FGA and three for D18S51 loci were found. In 10 cases (loci vWA, FGA, D18S51, D8S1179), the SGM plus and/or Profiler plus profiles showed homozygosity and the Powerplex16 genotype revealed heterozygosities which were confirmed to be true, both by typing with individual primer pairs and DNA sequencing. In four cases (two discrepancies at locus FGA, one at D18S51 and an abnormal paternity pattern for D5S818), the Powerplex16 kit showed apparent homozygosity and the SGM plus and/or Profiler plus kits showed heterozygosity. Mutation analysis could be performed for some of these individuals and evidenced variants, presumably leading to an annealing failure of one primer; the identified mutations are reported. It is suggested that databases should include information about the kits used to determine the profiles while ensuring that the primer sequences are made available.     

Transitional politics in Afghanistan and Iraq: inclusion,consultation, and public participation

This article explores three main themes in comparing the transitional processes in Afghanistan and Iraq: (i) the clarity of the transitional frameworks and the need to separate discussions on such frameworks from debates on new constitutional arrangements; (ii) the degree of representation in the transitional institutions and the availability of channels for political consultation in the transitional processes; and (iii) the participation of civil society and the public at large in the transition processes.     

Determination of the active principles of Catha Edulis: quali-quantitative analysis of cathinone, cathine, and phenylpropanolamine

In the last years, all the vegetable material supposed to belong to the Catha Edulis species, seized at the Malpensa and Orio al Serio airports, were analyzed in our laboratory on behalf of the Tribunals of Busto Arsizio and Bergamo, respectively. After a preliminary botanic examination, the quali-quantitative determination of the active principles cathinone, cathine and phenylpropanolamine (PPA) was carried out by means of GC/MS and GC/FID techniques, which meet the requirements of the forensic analyses. We developed a fast, effective and reliable derivatization procedure which allowed to simultaneously detect cathine and PPA, whose discrimination is mandatory since PPA is not a psychoactive agent. Cathine was distributed in the various parts of the plant (leaves and stems) and its quantity ranged from 0.03% to 0.17% of the weight of the vegetable material; PPA was not detected in the twigs and its quantity in the leaves ranged from 0.07% to 0.16%. The quantitative determination of cathinone was carried out directly on the methanol solution after maceration of the vegetable material, its quantity ranging from 0.02% to 0.10%. No significant difference in the content of the two active principles was found between the fresh and the dried material.     

Networks and political engagement of migrant organisations in five European cities

This article investigates networks and political actions by migrant organisations in five European cities. It examines how political opportunity structures moderate the impact of organisational networks on organisations' political contacts and protests using data from organisational surveys undertaken between 2005 and 2008 in Budapest, Lyon, Madrid, Milan and Zurich. Results suggest that the political context moderates the role that different types of networks have on mobilisation. It is found that migrant organisational networks may be sources compensating for the lack of contextual opportunities, thus fostering the use of protest by migrant organisations. However, migrant organisational networks can also favour the creation of political subcultures, marginalised from mainstream politics. Finally, migrant networks are likely to foster migrant organisations' political integration in multicultural contexts through conventional as well as non‐conventional politics.