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Little is known about the relative influences of neighborhood and school on the alcohol socialization process. Survey data from the Young in Oslo Study (N?=?10,038, mean age 17.1 years, 52% girls) were used to investigate the details of such influences, using cross-classified multilevel models. School and neighborhood contexts were equally important for ordinary alcohol use; however, neighborhood influences were mainly explained by individual and family factors, whereas peer-based sociocultural processes played a key role in explaining school effects. Neither context had much impact on heavy episodic drinking. The study suggests that “privileged” youth may be at risk of high alcohol consumption. Parental influences and peer-based sociocultural aspects of the school milieu should be considered in prevention efforts.  相似文献   
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This paper argues that recent developments in practice and theory provide a more promising basis for public service reform in developing countries than we have had since at least the turn of the century. There have been significant instances of large‐scale reform success, such as Nepal's Public Service Commission and Malaysia's delivery unit, Pemandu, and also “pockets of effectiveness” in individual agencies in many countries. They contribute to a more fruitful and diverse repertoire of reform approaches than generally realized. Policymakers can draw on all those instances and types of reform, together with relevant rich country experiences, as they improvise and tailor responses to their always unique reform problems. Proceeding in this way helps reformers to expand the “reform space” available within the political economy. Donors can help reformers if they facilitate reform in the spirit of the Busan Partnership rather than impose their preferred models. In short, the new direction which this paper identifies can be stated as creative problem solving by local actors facilitated by sympathetic donors, building on examples of reform success and drawing on a repertoire of poor and rich country reform approaches.  相似文献   
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Degradation of human DNA extracted from forensic stains is, in most cases, the result of a natural process due to the exposure of the stain samples to the environment. Experiences with degraded DNA from casework samples show that every sample may exhibit different properties in this respect, and that it is difficult to systematically assess the performance of routinely used typing systems for the analysis of degraded DNA samples. Using a batch of artificially degraded DNA with an average fragment size of approx. 200 bp a collaborative exercise was carried out among 38 forensic laboratories from 17 European countries. The results were assessed according to correct allele detection, peak height and balance as well as the occurrence of artefacts. A number of common problems were identified based on these results such as strong peak imbalance in heterozygous genotypes for the larger short tandem repeat (STR) fragments after increased PCR cycle numbers, artefact signals and allelic drop-out. Based on the observations, strategies are discussed to overcome these problems. The strategies include careful balancing of the amount of template DNA and the PCR cycle numbers, the reaction volume and the amount of Taq polymerase. Furthermore, a careful evaluation of the results of the fragment analysis and of automated allele calling is necessary to identify the correct alleles and avoid artefacts.  相似文献   
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The amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy" is a currently used or abused designer drug and fatalities are frequently encountered in forensic practice. However, the question remains open whether an MDMA blood level can be toxic or even potentially lethal. In order to provide insight in the interpretation of a detected MDMA concentration, the distribution of MDMA and its metabolite 3,4-methylenedioxyamphetamine (MDA) in various body fluids and tissues was studied and discussed in two different fatalities. Apart from peripheral blood samples (such as femoral and subclavian blood), various blood samples obtained centrally in the human body and several body fluids (such as vitreous humour) were examined. In addition, various tissues such as cardiac muscle, lungs, liver, kidneys, and brain lobes were analysed. In contrast to the peripheral blood levels, high MDMA and MDA levels were found in cardiac blood and the majority of the organs, except for the abdominal adipose tissue. The high concentrations observed in all lung lobes, the liver and stomach contents indicate that post-mortem redistribution of MDMA and MDA into cardiac blood can occur and, as a result, blood sampled centrally in the body should be avoided. Therefore, our data confirm that peripheral blood sampling remains "the golden standard". In addition, a distinct difference in peripheral blood MDMA concentrations in our two overdose cases was established (namely 0.271 and 13.508 microg/ml, respectively). Furthermore, our results suggest that, if a peripheral blood sample is not available and when putrefaction is not too pronounced, vitreous humour and iliopsoas muscle can be valuable specimens for toxicological analysis. Finally, referring to the various mechanisms of death following amphetamine intake, which can result in different survival times (e.g. cardiopulmonary complications versus hyperthermia), the anatomo-pathological findings and the toxicological results should be considered as a whole in arriving at a conclusion.  相似文献   
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A Linear Poisson Autoregressive Model: The Poisson AR(p) Model   总被引:1,自引:0,他引:1  
Time series of event counts are common in political scienceand other social science applications. Presently, there arefew satisfactory methods for identifying the dynamics in suchdata and accounting for the dynamic processes in event countsregression. We address this issue by building on earlier workfor persistent event counts in the Poisson exponentially weightedmoving-average model (PEWMA) of Brandt et al. (American Journalof Political Science 44(4):823–843, 2000). We developan alternative model for stationary mean reverting data, thePoisson autoregressive model of order p, or PAR(p) model. Issuesof identification and model selection are also considered. Wethen evaluate the properties of this model and present bothMonte Carlo evidence and applications to illustrate.  相似文献   
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Since the suicide—homicide of 53 members of the Order of the Solar Temple in 1994 and the gas attempt by Aum Shinrikyo in Tokyo's subway in 1995, a number of European states have decided to fight against sects. France and Belgium are in the forefront of this battle. Both countries have set up official observatories of sects and state agencies involving various ministries to combat them. Preventive policies targeting sects are being carried out. In Belgium, the Anthroposophic Society, a philosophical movement listed as 1 of 189 sects suspected of being dangerous, has sued one federal entity that printed unfounded accusations against their movement in a widely distributed brochure against sects. The same Anthoposophic Society has also petitioned the Court of Arbitration to have the law establishing an observatory of sects annuled. This report deals with both legal actions.  相似文献   
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Zusammenfassung  Viele l?ndliche Regionen sind mit einer Ausdehnung der Waldfl?chen konfrontiert. Dies wird vor allem dann als problematisch empfunden, wenn die betroffenen R?ume bereits waldreich sind. Zur Steuerung der Waldzunahmedynamik bieten sich verschiedene rechtliche Instrumente an, deren Potenziale derzeit nicht voll ausgesch?pft werden. Weiterentwicklungsm?glichkeiten bestehen insbesondere im Hinblick auf die Normen zur Aufforstungsgenehmigung. Hier ist ein grunds?tzlicher normativer Paradigmenwechsel denkbar. Neureglungen k?nnten aber auch über die Einrichtung einer Experimentiergesetzgebung zun?chst beispielhaft erprobt werden. Der Beitrag entwickelt zudem einen Leitfaden für die Beurteilung einer “erheblichen Beeintr?chtigung des Landschaftsbilds”, einem bisher nicht ausreichend konkretisierten Versagungsgrund für eine Aufforstungsgenehmigung.  相似文献   
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