Ethyl Glucuronide Concentration in Hair of Detainees: A Preliminary Study

Through the measurement of ethyl glucuronide in hair (hETG), it is possible to assess chronic alcohol abuse over time. In this paper, we present a study on hETG in Italian prison inmates. Analyses were performed by LC-MS according to a previously published method. Results were evaluated using the cut-offs established by the Society of Hair Testing. Positives samples (ETG > 30 pg/mg) accounted for 6% of all subjects, with concentrations ranging from 42 pg/mg up to 270 pg/mg, abstinent subjects (ETG < 7 pg/mg) accounted for 88%, and moderate alcohol consumption (7 < ETG < 30 pg/mg) for 6% of the subjects. No females displayed ETG values above 30 pg/mg. Among positive samples, only two subjects did not declare heavy alcohol consumption and were found strongly positive at 210 and 270 pg/mg. To the best of our knowledge, this represents the first study on ETG hair concentration on prison inmates.     

A New Paradigm

<正>The"Four Comprehensives"aim at putting China on track to achieve its economic and social development targets.In an effort to avoid a hard landing from the economy,China should face the current downward pressure on its growth by boosting effectivedemand and progressively switching to a new growth model.At the opening of the annual National People’s Congress(NPC)in March,Chinese Premier Li Keqiang announced that the of-     

"Vaginal" bleeding in prepubertal age: a rare scaring riddle, a case of the urethral prolapse and review of the literature

The entities responsible for isolated vaginal bleeding are a broad spectrum of diseases. Vaginal bleeding in a prepubertal child is always treated as an alarming symptom both by parents and professionals. Most often, one of the first hypotheses is that a sexual abuse may be occurred and the clinical work up is oriented to explore it and eventually confirm or substantiante another diagnosis. Among the possible differential diagnosis urethral prolapse has to be considered. We report the case of a 6 years-old Caucasian girl referred to our Service for a mild vaginal bleeding and with the suspicion of sexual abuse, excluded after the confirmation of the presence of urethral prolapse. The clinical picture and workup are described and compared with a review of the international literature on the issue.     

Linguistic justice in IP policies: evaluating the fairness of the language regime of the European Patent Office

Alternative intellectual property laws relating to the use of languages in IP organisations can result in an asymmetric distribution of costs of patenting between innovators. We present a framework for the characterisation and evaluation of the fairness of the language regime of the European Patent Office (EPO), which is currently based on three official languages: English, French and German. We estimate that the costs of access to patenting procedures borne by English-, French- or German-speaking applicants are at least 30 % lower than those borne by European applicants whose first language is not one of the current official languages of the EPO. In order to correct language-related cost asymmetries, we explore two possible alternative language regimes. In both cases, we introduce a centralised system of financial compensation that covers translation costs borne by European applicants whose first language is not one of the official languages of the EPO. In the first alternative, financial compensation is covered by savings on current translation costs at the granting stage. In the second alternative, the number of official languages is increased to five and financial compensation is funded by an increase in filing fee and by partial savings on translation costs at the granting stage. We show that both alternatives could substantially reduce language-related costs asymmetries among European applicants. In addition, we show that the five-language alternative would reduce the global costs of access to patenting procedures borne by all European applicants. Thus, more multilingualism can be cheaper than less multilingualism, provided that “implicit costs” are taken into account. We conclude discussing under which conditions the alternative language regimes proposed could have a positive impact on the effectiveness and the cost-effectiveness of the EPO language regime.     

Suicidal Smothering by Rubber Latex Gloves and Handkerchief

Asphyxial deaths are common in forensic practice, being sustained by a variety of mechanisms that cause an oxygen deficiency to the brain. Several classification models have been proposed in the literature, the most recent one being that of the International Network for Forensic Research Group (INFOR). This report describes an unusual case of suffocation where the obstruction of the airways was caused by a gag formed of three latex gloves and a handkerchief. The manner of death (differential diagnosis between homicide and suicide) and the different alternatives of classification are discussed.     

Criminological and Medico-legal Aspects in Homicidal and Suicidal Sharp Force Fatalities

The interpretation of sharp force fatality dynamics may be difficult in some cases, but a contribution to analysis of the phenomenon may be provided by case studies. Therefore, the purpose of our study is focused on identifying, in observed sharp force fatalities, reliable parameters that can differentiate a homicidal and suicidal manner of death, with particular reference to criminological parameters. Data derived from sharp force fatality cases in Padua and Venice from 1997 to 2019, anonymized and collected in Excel, included personal, circumstantial, clinical, and psychopathological–criminological data, as well as crime scene investigation, necroscopic, and toxicological data. Statistical analyses were performed using chi-square and Wilcoxon rank-sum tests. Possible predictors of homicide were analyzed by logistic regression. Six parameters (bloodstains distant from the body, clothing lacerations, hesitation/defense wounds, number of injuries, and potential motives) were significantly different in the two groups (p < 0.05). An independent statistical association between potential motives explaining the crime (p < 0.001; OR 27.533) and homicide on multiple logistic regression analysis was highlighted. The absence of clothing lacerations was inversely related to homicide (p = 0.002, OR 0.092). To the best of our knowledge, this is one of very few Italian studies concerning the differential diagnosis between homicidal and suicidal sharp force fatalities. The dynamics of the event is established in most cases by the integrated evaluation of data from crime scene investigation and the autopsy. Nevertheless, in an atypical scenario, a psychopathological–criminological analysis may provide essential elements, and particular attention should be given to the identification of potential explanatory motives.     

Multi-Rater Agreement Using the Adapted Fracture Healing Scale (AFHS) for the Assessment of Tubular Bones on Conventional Radiographs: Preliminary Study*

Better understanding of the timing of fracture healing may help in cases of interpersonal violence but also of personal identification. The intra- and inter-rater agreement for the adapted fracture healing scale (AFHS) assessing the post-traumatic time interval on radiographs were tested. This is a preliminary study, providing essential information on method reliability for upcoming studies using the AFHS. Five raters (two radiologists, a forensic pathologist, an orthopedist, and an anthropologist) were presented with a test in three parts consisting of 85 radiographs (from 30 adults) of fractures of tubular bones in different stages of healing purposefully selected from more than 1500 radiographs. The raters were firstly asked to assess 15 features describing fracture healing as present, absent, or not assessable. Thereafter, the raters were asked to choose from the AFHS a single-stage best representing the observed healing pattern. The intra- and inter-rater agreement were assessed using single-rating, absolute agreement, two-way mixed-effects intra-class correlation (ICC) coefficients. The intra-rater ICC of radiologist 1 ranged from 0.80 to 0.94. The radiologists’ inter-rater ICC ranged from 0.68 to 0.74, while it ranged from −0.01 to 0.90 for the other raters. The good to excellent ICC among the radiologists and forensic anthropologist provides good foundation for the use of the AFHS in forensic cases of trauma dating. The poor to good results for the other physicians indicate that using the AFHS requires training in skeletal anatomy and radiology.     

The Impact of ‘New Technology' on the ‘Red Brigades' Italian Terrorist Organisation

The analysis of the ‘New Technology' (NT), as a highly potent set of criminal instruments is becoming more and more relevant. In fact, the most recent expressions of both National, European and International Terrorism have revealed a progressively wider use of goods and services related to NT. The present article studies the several forms of NT exploitation by the ‘Red Brigades' (BR), Italian terrorist group. The information collected is the result of a cross-analysis of doctrine; privileged witness interviews (experts and investigators); participant's observation of websites created by terrorist and subversive movements, sharing the same ideology at the base of the BR organisation and Journal articles on the latest successes by police against the BR, as well as the evaluation of the confiscated technological material. The result is a qualitative view of the interaction between NT and BR phenomenon, in the light of the increasing importance of specific technological tools, carefully selected by the criminal organisation to achieve pragmatic and contingent goals. It is relevant also to anticipate two series of conclusions: first, we show the substantial willingness of the ‘new generation' of BR to search for alternatives to traditional channels of communication, finding in NT, Internet in particular, a valid support, as it provides new and more anonymous vehicles of information exchange, inside and outside the organisation itself. A close ideological connection with a new transnational phenomenon is evident: the Urban Subversive Associations (Black-Block, Anarchic-Insurrectional). Young people with a high degree of technological skill form a potential ‘cradle' of recruitment for the BR movement.     

Selectivity on aid modality: Determinants of budget support from multilateral donors

Since the late 1990s a selection on policy approach to aid was advocated such that more aid should be allocated to countries with good policies, but there is little evidence that this has occurred. This paper argues that donors may exercise selectivity over the aid modality. Specifically, multilateral donors will cede more recipient control over aid by granting more budget support to those recipients with better expenditure systems and spending preferences (towards the poor) aligned with the donor. We test this for European Commission and World Bank budget support over 1997?C2009 and find some support. Both donors have given budget support to almost half of the countries they give aid, and it is usually a significant share of their aid. The principal determinants of receiving budget support are having a poverty reduction strategy in place, which can be considered a good indicator of aligned preferences, and indicators of government efficiency. These variables did not, however, influence the amount of budget support given. Multilateral donors have been more likely to give budget support to countries with aligned spending preferences and better quality systems, even if they have not reallocated the total aid envelope in that way.