Le Parlement en temps de crises politiques dans le royaume de Portugal (XIV-XVe siècles)

SUMMARY

This article focuses on the role of the Cortes in the course of two decisive moments of the Portuguese monarchy: the choice of a king on the one hand and the decision to accept a regency on the other. The Cortes of Coimbra (1385) are first analysed in the context of the political events that preceded them, in terms of the novelty of being summoned by the social forces of the kingdom, and in terms of their ideology and innovative measures. As a result, a king was chosen—King John I, the founder of the House of Avis—and reforms of a noticeable ‘constituent’ tendency were proposed. Attention is then focused on the Cortes of Lisbon (1439), which were equally unusual in their summoning and performance. There, it was decided that the infant Don Pedro, brother to the late king Don Duarte, would be in charge of the regency while the heir to the throne, Don Afonso V, was not yet of age. This prevented the queen from occupying the role the monarch had intended for her. In both cases these Cortes are very special given that they legitimated revolutionary acts which had previously taken place. This behaviour reinforces the idea that by comparison with other kingdoms in the Iberian Peninsula, the Portuguese Cortes had a strong leadership role in moments of political crisis and in the assertion of the power and social formation of the monarchy.     

母鼠妊娠期铅镉联合暴露对仔鼠脑组织的氧化损伤及乙酰半胱氨酸的保护效应

45只怀孕SD母鼠被随机分为9组,即A组(对照组,饮用蒸馏水)、B组(铅组,300 mg/L)、C组[铅 N-乙酰半胱氨酸(N-NAC)组,300 mg/L 20 mmol/L]、D组(镉组,10 mg/L)、E组(镉 NAC组,10mg/L 20 mmol/L)、F组(低剂量铅镉联合组,150 mg/L 5 mg/L)、G组(低剂量铅镉联合 NAC组,150mg/L 5 mg/L 20 mmol/L)、H组(高剂量铅镉联合组,300 mg/L 10 mg/L)、Ⅰ组(高剂量铅镉联合 NAC组,300 mg/L 10 mg/L 20 mmol/L).采用饮水染毒,染毒时间为21 d,分娩后每窝随机选取6只乳鼠测定脑匀浆超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GSH-Px)、乙酰胆碱酯酶(TChE)活性和丙二醛(MDA)的含量.结果表明,低剂量铅镉联合作用具有中间效应(介于铅、镉单独毒性作用之间),而高剂量铅镉联合作用表现协同或叠加效应.NAC拮抗组与染毒组比较,MDA含量显著降低,SOD、GSH-Px、TChE、CAT活性有升高趋势,说明NAC可以提高大鼠的抗氧化能力,对母鼠铅镉暴露所致新生鼠脑脂质过氧化损伤有一定的保护作用.     

A novel histological technique for distinguishing between epithelial cells in forensic casework

There are a number of forensic cases in which the identification of the epithelial cell type from which DNA originated would provide important probative evidence. This study aimed to develop a technique using histological staining of fixed cells to distinguish between skin, buccal and vaginal epithelium. First, 11 different stains were screened on formalin-fixed, wax-embedded cells from five women. Samples were analysed qualitatively by examining staining patterns (colour) and morphology (absence or presence of nuclei). Three of the staining methods – Dane's, Csaba's and Ayoub-Shklar – were successful in distinguishing skin epithelial cells from buccal and vaginal. Second, cells were smeared directly onto slides, fixed with one of five fixatives and stained with one of the three stains mentioned above. Methanol fixation, coupled with the Dane's staining method, specific to keratin, was the only technique that distinguished between all three cell types. Skin cells stained magenta, red and orange and lacked nuclei; buccal cells stained predominantly orange–pink with red nuclei; while vaginal cells stained bright orange with orange nuclei and a blue extracellular hue. This staining pattern in vaginal cells was consistent in samples collected from 50 women aged between 18 and 67. Identification of cell type from unlabelled micrographs by 10 trained observers showed a mean success rate of 95%. The results of this study demonstrate that histological staining may provide forensic scientists with a technique for distinguishing between skin, buccal and vaginal epithelial cells and thus would enable more conclusive analyses when investigating sexual assault cases.     

A Fossilised Constitution?

Abstract.  The purpose of this paper is to analyse the limits of constitutional reform. Some constitutions, for example, the German (art. 79, sec. 3), the Italian (art. 139), the Portuguese (art. 288), the French (art. 89, sec. 5), and the Brazilian (art. 60, sec. 4), contain an "essential core" of rights, which is usually understood as being immune to change. The initial focus in the paper is on the discussion on whether and to what extent these "essential cores" are indeed immune to change. A second focus is on Ross's paradox. Here I analyse and reject Ross's own solution to the paradox and I show, too, that the paradox admits no solution that does not imply a discontinuity in the legal system.     

Invitation or Ambush: The Scope of an Insured's Duty to Cooperate and the Slippery Slope of Information Sharing

The policyholder's “duty to cooperate” is built into every liability insurance policy, either expressly or through the application of a state's common law. The scope of an insured's duty to cooperate is often difficult to discern, however, in terms of the type and extent of information that the insured should provide as part of the insurer's investigation of the underlying matter for which coverage is being sought. Traditionally, the duty to cooperate was intended to encourage information sharing to allow the insurer to afford the policyholder a comprehensive, informed defense to the underlying claimant's allegations. This article examines the scope of the duty to cooperate and how that duty impacts the insured's obligation to share some reasonable amount of information as part of the insurer's investigation and defense of the underlying claim, noting potential pitfalls and risks that may arise from information sharing.     

TRENDS IN FEMALE DELINQUENCY

National arrest statistics combined with juvenile court, self-report, and field observational data are used to evaluate current conceptions of the changing nature of female delinquency. Adolescent females made arrest gains in the categories of larceny (e.g., shoplifting). liquor law violations (e.g. underage drinking), and runaways. Studies of juvenile gangs show no increase in female violence or gang-related delinquencies while self-report data show that, with the exception of marijuana use and drinking, female delinquency has remained generally stable over the past decade. We conclude that patterns of female delinquency, especially as revealed in nonofficial sources of evidence, have changed very little in recent years and that female delinquency continues to reflect traditional sex roles. The evidence suggests that the Women's Movement has had little or no effect on female delinquency. At the end of the report. we suggest alternative views regarding female delinquency and the forces shaping it.