Academic entrepreneurship: founding and governance determinants in university spin-off ventures

The Journal of Technology Transfer - Academic research is generally seen as one of the most important goals of a university, but universities are being called upon simultaneously to assist in...     

External Pressures and Internal Dynamics in the Institutionalization of Performance-Based Budgeting: An Endless Process?

The well-known practice of performance-based budgeting (PBB) is a relevant component of the New Public Management (NPM) reform agenda and has become widespread, with varying approaches and results across countries. However, its variation within specific countries has remained largely unexplored. This study analyzes three organizations operating within the same context—three ministries in Italy—to contribute to a new understanding of PBB variation by illustrating why the same PBB practice can or cannot be implemented and internalized similarly across these organizations and thus become (or not) fully institutionalized. The study adopts and enriches the institutional approach by extending beyond isomorphic convergence toward PBB and explaining practice variation, linking the interactions between external pressures and internal dynamics at the organizational level to PBB institutionalization. The empirical analysis shows how a lack of alignment between external pressures and internal dynamics contributes to an unfinished and apparently endless process of institutionalization.     

Whole Plastome Sequences of Two Drug-Type Cannabis: Insights Into the Use of Plastid in Forensic Analyses

DNA is one of the fastest growing tools in forensic sciences, increasing reliability in forensic reports and judgments. The use of DNA has increased in different areas of the forensic sciences, such as investigation of plant species, where plastid DNA has been used to elucidate and generate evidence in cases of traceability of genetically modified and controlled plants. Even with several advances and the practice of using DNA in forensic investigations, there are just few studies related to the identification of genetic tools for the characterization of drug and nondrug-types of Cannabis. Herein, the whole plastomes of two drug-type Cannabis are presented and have their structures compared with other Cannabis plastomes deposited in the GenBank, focusing in the forensic use of plastome sequences. The plastomes of Cannabis sativa “Brazuka” and of the hybrid Cannabis AK Royal Automatic presented general structure that does not differs from the reported for other C. sativa cultivars. A phylogenomic analyses grouped C. sativa “Brazuka” with the nondrug C. sativa cultivars, while the hybrid Cannabis AK Royal Automatic placed isolated, basal to this group. This suggests that the analysis of plastomes is useful toward genetic identification of hybrids in relation to C. sativa.     

What is the best sample for determining the early postmortem period by on-the-spot flow cytometry analysis?

The level of degradation of DNA as a means for determining the time of death has been proposed as a valid adjunct to the classic thanatochronologic methods. The twofold aim of this work was to determine which organ might reveal both a correlation between the percentage of degradation of the DNA and the time lapse since death, and would be easiest to sample and yield the most reproducible results even in technically unfavorable situations such as on-the-spot investigations at the scene of death. A comparison of the spleen, blood, and liver showed that hepatic tissue best meets these specific needs because it shows a virtually linear correlation between the time elapsed since death and the level of degradation of the DNA, and it can easily be sampled at the scene of death by use of a common biopsy needle.     

Religiöse Diskurstraditionen

Die jüngere Forschung zum sozialen Handeln von Muslimen in westeuropäischen Einwanderungsländern hebt häufig die reflexive Individualisierung von Lebensformen und religiösen Gesinnungen vor allem junger Muslime hervor. Der folgende Beitrag hinterfragt die diesem Ansatz zugrunde liegende Annahme eines Wertekanons ziviler europäischer Gesellschaften und Öffentlichkeiten, in die sich in Europa sozialisierte junge Muslime vermeintlich einfügen und muslimische Identitäten ?europäisch“ rekonstruieren. Dieser Transformationsprozess wird in diesen Theorien sowohl im Hinblick auf die familiale Lebenswelt wie im Hinblick auf die öffentliche Sphäre, in denen Muslime agieren, unterschätzt. Im Rückgriff auf Ansätze der historisch-vergleichenden Soziologie und der Religionsanthropologie erarbeitet der Aufsatz zunächst einen Begriff von ?Tradition“, der die Konstituierung, Verwaltung und Transformation von religiösen Diskursen, Praxen und Subjekten diachronisch und transgenerationell erklärt und der Gleichzeitigkeit von sozialer Einbettung und diskursiver Autonomie von Tradition Rechnung trägt. Wir zeigen, dass die sozialen Praktiken von Muslimen in Europa eine Transformation erfahren, die ihre besondere Grundlage im muslimischen Reformdiskurs im kolonialen und postkolonialen Kontext mehrerer Zentren der islamischen Welt hat. Der Fall junger Kopftuch tragender Musliminnen in Deutschland und Frankreich, die der zweiten und dritten Migrantengeneration angehören, zeigt schließlich weder eine selbst-reflexive Identitätssuche noch das ?coming out“ der Heldinnen einer nicht-westlichen Modernität, sondern ein praxisorientiertes und wissensgestütztes Räsonieren der jungen Frauen über die Wiedereinbettung des Traditionsdiskurses in die sozialen Felder (Familie, Studium, Arbeit und islamische Vereine), in denen sie operieren. Ihr Streben, das von der Traditionsdynamik der Kohärenzsuche geleitet wird, konfiguriert eine ?Alltagspolitik“, in der die Frauen ihre islamisch inspirierten Lebensprojekte gleichzeitig von moralisch erstarrten familiären ?Lebenswelten“ und von normativ erstarrten politischen Öffentlichkeiten abkoppeln und kultivieren.     

Demonstration of a gastric bioptic specimen mix-up by laser capture microdissection (LCM) and DNA fingerprinting

We demonstrate here the successful use of laser capture microdissection (LCM) and DNA fingerprinting in the identification of a case of gastric bioptic specimen mix-up. A 70-year-old man, suffering from chronic atrophic gastritis, underwent to a gastric biopsy and received a diagnosis of gastric cancer. In the absence of any clinical evidence of gastric cancer, a specimen mix-up was suspected. LCM was used to retrieve gastric cells from the histologic slide, classified as gastric carcinoma, and suspected to be mislabelled. DNA was extracted from microdissected cells, and a total of 16 different genetic loci were analyzed, using an identity test. Comparison of the results with those obtained using DNA extracted from a control slide, and from patient's saliva, demonstrated a distinct DNA fingerprint pattern in all genetic markers examined, clearly indicating the occurrence of a specimen mix-up. The combined use of LCM and DNA fingerprinting represents the most accurate and sophisticated method available for the identification of specimen mix-up, especially when only the tissue on the suspected slide is available.