The British mosquito eradication campaign in colonial Lagos, 1902-1950

The impact of malaria on the demography of European settlers in Lagos from the mid-nineteenth century posed a serious threat to British imperialism in Nigeria. This prompted the British administration to take vigorous measures to address the unsanitary conditions within Lagos, a major causation of the disease. This paper examines the colonial programmes on the eradication of mosquitos in Lagos, the colonial capital of Nigeria. It highlights the political and economic implications of this programme, and the responses of African colonial subjects to the initiative. The government adopted divergent solutions, ranging from racial segregation to swamp reclamation. However, each of these had a downside. Segregation policies, at a time of growing nationalism among an increasingly politically conscious African educated class, would breed political unrest. Swamp reclamation, on the other hand, would require seizing privately owned land and depriving fishermen and wood collectors who earned a living by exploiting the resources of these swamps, critical for their survival and for the colony’s coffers. When the colonial administration finally settled on swamp reclamation, it faced the problem of cost that needed to be balanced with the sacrosanct principle that colonies should be self-sustaining economies and not be a burden to the metropolis. Existing studies have overlooked the resistance or reaction of Lagosians to swamp clearance and forest ordinance. The paper relies on a combination of primary, secondary and oral sources, including a body of archival documents and some interviews.     

The deferred promise of radical cure: pharmaceutical conjugations of malaria in the global health era

Abstract

This paper explores the changing political economy of malaria drug discovery by tracing the career over the last four decades of a single molecule, tafenoquine. First identified as a promising antimalarial by the US Army in the 1970s, tafenoquine has recently been approved by the Food and Drug Administration for the radical cure of vivax malaria – the first product to receive marketing authorization for this indication in more than 65 years. The new drug is the result of a collaboration between the pharmaceutical company GlaxoSmithKline and the not-for-profit organization Medicines for Malaria Venture, with the financial support of the Bill and Melinda Gates Foundation. The successful development of tafenoquine, the paper argues, signals an important transition within the global health era: from the chemotherapeutic humanitarianism that characterized pharmaceutical efforts against malaria in the early 2000s, towards a period of drug discovery driven by the promise of global disease eradication. The paper uses the example of tafenoquine to advance a more general argument about the multiple and evolving pharmaceutical conjugations of malaria – the articulation of competing visions of the disease around the capabilities (and limitations) of particular molecules.     

The European Union and transnational health policy networks: a case study of interaction with the Global Fund

This article examines the nature of the engagement between the European Union and the Global Fund created to combat HIV/AIDS, tuberculosis and malaria. The authors reveal that in relations between the EU and the Fund, influence is reciprocal although asymmetrical with the EU commanding more leverage. They also contend that the EU considers its engagement with the Global Fund as successful to the extent that the success of this interaction is contingent on the Global Fund's capacity for implementation. They conclude that the relationship between the EU and the Fund will continue for the foreseeable future.     

An Autopsy Case of Sudden Unexplained Death Caused by Malaria*

Abstract: Sudden unexplained deaths, especially those unwitnessed can lead to forensic issues and would necessitate the need for a meticulous and complete postmortem examination including ancillary investigations to discover the cause of death. We herein report a case of sudden unexplained death caused by malaria in an apparently healthy individual. This fatal case is presented to remind the forensic pathologist of the possibility of malaria as a cause of sudden unexplained death in malaria‐endemic regions. In the present case, histopathological examination demonstrated the presence of parasitized red blood cells with malarial pigment in the blood capillaries in the brain, myocardium, pericardium, lungs, kidneys, liver, and the spleen. Cerebral malaria with acute renal insufficiency or pulmonary edema with an acute respiratory distress syndrome might have been the cause of death.