Spleen and portal lymphnode pathology in fatal drug addiction

Spleen and portal lymphnode sections from 86 drug addicts submitted for medico-legal autopsy at the Institute of Forensic Medicine in Copenhagen in the year 1979 were studied together with tissue sections from 24 "normal" persons. In 70% of the drug addicts the spleen weight was more than 200 g, and in 71% portal lymphnode hyperplasia was found. Birefringent foreign material was found in spleen tissue of drug addicts in 72% and in portal lymphnode tissue in 44%. Signs of antigen stimulation in both spleen and portal lymphnode tissue evaluated by the number of germinal centre and plasma cells were found in more than 80% of the drug addicts compared with about 20% of the "normal" persons. The results were related to anamnestic information of duration of drug abuse, to the spleen weight, to the occurrence of birefringent material and to the liver changes. Examination of lysozyme and immunoglobulin containing cells using the indirect preoxidase technique was performed in a total of 72 cases of spleen tissue, 59 cases of portal lymphnode tissue from drug addicts, 24 cases of spleen tissue and 18 of portal lymphnode tissue from "normal" persons. Lysozyme, IgM and IgG containing cells were found significantly more often among drug addicts than "normal" persons. The results indicate that the splenomegalia and the portal lymphnode hyperplasia often found in drug addicts are caused by continuous antigen stimulation due to repeated injections of various antigens.     

A spatial analysis of county-level outcomes in US Presidential elections: 1988–2000

This paper identifies spatial patterns of county-level presidential election outcomes from 1988 to 2000, and tests the retrospective (reward–punishment) and issue–priority models of voting behavior within the context of county-level geographical clusters. Based on our spatial analyses, we find that: the geographical concentration of the partisan vote has increased at both the global and regional scales. Globally, counties have become more likely to be clustered with similar counties in terms of their partisan support. Regionally, Democrats have increasingly received more votes from the East and the urban areas than Republican candidates while the opposite is true in the West and the rural areas. The regression analyses also support aspects of the issue–priority model of voting behavior, while the retrospective theory is confirmed only for 1996.     

Interorganizational Collaborations for Humanitarian Aid: An Analysis of Partnership,Community, and Single Organization Outcomes

Abstract

This article explores collaborative activities across organizational and sectoral boundaries. Interorganizational collaborations are an increasingly common setup to address societal needs; however, current research lacks insights into such collaborations and their outcomes. This study contributes to the existing literature by assessing empirically perceptions of interorganizational collaboration outcomes, considering different dimensions that should be measured when planning and performing tasks of social interest. The article is set in the context of disaster relief, where actors from different humanitarian relief organizations within the public and nonprofit sector engage in collaborative activities. I describe how interorganizational collaborations create outcomes for (1) the partnership structure that is established, (2) single organizational members involved in the collaborative activity, and (3) the community targeted by the interorganizational operation.     

69例男性阴部损伤分析

从致伤原因、致伤工具、损伤类型等方面对69例男性阴部损伤案进行了统计分析．     

A fatal poisoning with LSD

Radioimmunoassay, high-performance liquid chromatography and capillary gas chromatography-mass spectrometry were used to detect and measure LSD in the first reported case of fatal poisoning by LSD. The levels found in ante-mortem serum and plasma and in post-mortem blood, liver blood and stomach contents are given.     

Searching for Equilibrium: The Tenuous Nature of the Outcome Test

Based on Engel's critique of the outcome test and Persico and Todd's response, the underlying assumptions critical to the outcome test are summarized and discussed. It is argued that many of these assumptions are not met when applied to police search data. The key underlying assumption—the principle of equilibrium—is examined in detail, and several additional concerns are raised. Thereafter, the proper interpretations of outcome test analyses are reiterated, and discussion regarding the types of racial bias demonstrated by these analyses is further explored.     

What does it mean to suffer loss? Haxton v Philips Electronics

In Haxton v Philips Electronics the Court of Appeal considered whether a widow could recover the diminution in value of her dependency claim following the defendant's tortious reduction of her life expectancy. The note outlines the development of the common law, demonstrating that Haxton is novel but not unorthodox, and tests whether Haxton's principles can provide a sound foundation for future cases. Positing three hypothetical scenarios, it argues that the disparity in outcome, rather than indicating a lack of unifying principle, as was suggested in Jobling v Associated Dairies, may be explained by combining Austin's division between primary and secondary rights with Gardner and Stevens' contributions as to how they are protected. Restitutio in integrum requires consideration of the reasons and values underlying the right in question and these are discernible in the jurisprudence. The note also considers whether Haxton could have been decided on the basis that a defendant should not profit from its own wrongdoing.     

Effectiveness of modified therapeutic community treatment within a medium-secure service for personality-disordered offenders

There is debate as to whether secure hospital treatment for offenders with personality disorder can be effective relative to criminal justice interventions. This study examines the evidence for long-term treatment of such offenders in hospital within in a modified therapeutic community model including accredited offending behaviour programmes. A panel sample of 47 patients were followed up on measures of violence risk (HCR-20, VRS) and symptom severity (SCL90-R). Intention-to-treat analysis with reliability thresholds showed significant positive change between assessment and discharge in both violence risk (VRS) and symptoms (SCL90-R) indicating a positive treatment effect. Threshold effects for treatment effectiveness seemed to occur at 1?year of treatment for risk and 3?years for symptom reduction.     

Equity: Effects of Input and Outcome Orientation on Taking, Giving, and Dividing Money

Participants who were more inclined to consider ambiguous work elements as inputs (input-oriented or Type-I persons) or as outcomes (outcome-oriented or Type-O persons) were presented with situations in which they had delivered a higher or lower work performance than another person. They were asked to take money for themselves, give money to the other person, and divide a fixed sum of money between themselves and the other as reward for the performances. The specific combination of (input or outcome) orientation of the participant and the type of transfer (giving, taking, or dividing) determined the reward the participant allocated to him- or herself and/or to the other person. Type-I persons showed an egocentric bias in their allocation behavior, whereas Type-O persons allocated according to a maximin strategy.