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《Forensic Science International: Genetics Supplement Series》2013,4(1):e73-e74
In order to increase the information about Indels, we report allele frequencies and statistical parameters of forensic efficiency obtained typing a sample of 114 unrelated healthy individuals living in San Basilio de Palenque – Colombia using a panel of 38 autosomal InDels. No significant deviations from Hardy–Weinberg expectations were found except in the marker rs10629077 (p = 0.0002). The present database will be useful for forensic and paternity purposes for the region studied. Moreover, these additional markers can help forensic laboratories to solve parentage testing as well as to improve the analysis of degraded DNA samples. 相似文献
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《Forensic Science International: Genetics Supplement Series》2013,4(1):e170-e171
This paper presents the genetic characterization of the Embera-Chami Amerindian community of Lapo-Antioquia-Colombia using 38 autosomal Indels. This group of markers showed a high discriminatory power (>99.9999%) and an appropriate power of exclusion (99.40%), allowing the use of these markers in the field of forensic genetics in this population. 相似文献
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目的调查Qiagen Investigator@ DIPplex试剂盒30个InDels多态性位点在中国汉族、藏族、维吾尔族人群中的群体遗传学数据,评估其法医学应用价值。方法采集汉、藏、维吾尔族各90名无关个体静脉血,提取DNA。使用3130xL毛细管电泳对该270份样品进行分型,通过统计计算相关的群体遗传学参数。结果实验得到270份样品的分型及基因型频率,30个InDels未明显偏离Hardy-Weinberg平衡及连锁平衡,在汉族、藏族、维吾尔族三个人群中的随机匹配概率分别为1.42×10(-11)、7.19×10(-12)、4.74×10(-13),累积非父排除率(CPE)均大于0.9951。结论该组插入缺失位点在中国的汉族、藏族、维吾尔族人群中具有较高的多态性,能达到较高的个体识别能力,可以作为现有STR检验体系的补充。 相似文献
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