肺气肿肺气虚证大鼠血气分析、血中细胞因子及肺组织病理学的改变

目的 :探索肺气虚证的本质。方法 :将 6 0只大鼠随机分为模型组与对照组 ,复制肺气肿肺气虚证模型 ,分别检测 pH、氧分压 (pO2 )、氧饱和度 (SaO2 % )、二氧化碳分压 (pCO2 )、白细胞介素 6 (IL 6 )、白细胞介素 8(IL 8)、肿瘤坏死因子 α(TNF α)及肺组织病理学的改变。结果 :模型组pH、pO2 、SaO2 %下降 ,pCO2 升高 ,与对照组比较 ,差异有显著性 (P <0 .0 1 ) ;模型组IL 6、IL 8、TNF α升高 ,与对照组比较 ,差异有显著性 (P <0 .0 1 ) ;病理组织学及超微结构检查显示肺组织有慢性支气管炎及肺气肿病变。结论 :肺气肿肺气虚证大鼠存在低氧血症和高碳酸血症 ,血中细胞因子IL 6、IL 8、TNF α升高 ,可能是肺气虚证从轻度向中、重度发展的重要原因之一。     

法治的实现目标及其途径

法治社会的价值目标是追求民主、平等;法治的核心问题是约束、限制权力;法治国家的本质特征是体现民治;实现 法治化的基本途径是建立安全、方便、经济的参政方式。     

电子商务中知识产权的法律保护

电子商务活动对社会的多个方面造成了很大的影响,也对传统的知识产权保护内容、保护方式、具体的原理及制度构建等方面提出了新的要求。在立法尚未完善的情况下,司法为拓宽电子商务领域知识产权保护做了一定的探讨。建立完善的电子商务自律机构和规则、逐渐完善相关的立法、加大对侵权行为的打击力度、协调国际上的知识产权保护,是发展电子商务并充分保护知识产权的有效途径。     

堆型艾美球虫广东株3-1E基因的克隆与序列分析

根据GenBank中登录的堆型艾美球虫31E基因序列,设计了3条引物,以广东株堆型艾美球虫裂殖子总RNA为模板,利用反转录聚合酶链反应(RTPCR)扩增获得了31E基因部分片段,将这一片段克隆至pGEMTEasy载体中,经PCR、限制性内切酶分析和克隆片段的序列测定、比较,证实了克隆片段的可靠性。序列比较发现,所克隆的基因片段与Eimeriaacervulina美国株(US)、E.acervulinaQH株31EcDNA的核苷酸同源性分别为99.0%和99.2%,推导氨基酸的同源性分别为98.2%和97.6%。     

Anspruch der Eigentümergemeinschaft auf Herausgabe der Verwaltungsunterlagen nach Kündigung des WE-Verwalters

Der gekündigte WE-Verwalter ist verpflichtet, nach beendetem Verwaltungsverh?ltnis der Eigentümergemeinschaft die Original-Verwaltungsunterlagen auch für bereits abgeschlossene Abrechnungsperioden herauszugeben. Der Herausgabeanspruch ist – entgegen der E 5 Ob 115/05f: streitiger Rechtsweg – nach nunmehr gefestigter Rsp auf Grund schlüssiger Verweisung des § 52 Abs 1 Z 6 WEG 2002 im wohnrechtlichen Au?erstreitverfahren geltend zu machen.     

Schadenersatzreform – Gefährdungshaftung und Unternehmerhaftung

Der Entwurf eines neuen ?sterreichischen Schadenersatzrechts sieht Regelungen der Gef?hrdungshaftung sowie der Unternehmerhaftung vor. Der Beitrag untersucht die jeweilige Ausgangslage, das Reformanliegen und die Konsequenzen einer Reform.     

Coping with an unjust fate: The case of structural unemployment

Becoming a victim of structural unemployment means suffering an unjust fate. The present research examines the cognitive reactions subjects use to protect their belief in a just world and the related effects on their actual well-being within a sample of unemployed blue-collar workers in East Germany (all female). Results showed that the belief in a just world was positively correlated with attributing one’s unemployment to one’s own behavior and negatively with asking “why me?”, but uncorrelated with subjects’ readiness to change into another profession in order to get employed. Just world belief and depression were negatively related for those who either avoided the “why me?” question or who found an answer to it; but just world belief and depression was positively related for those women ruminating about an unanswered “why me?”. Results are consistent with the idea that the belief in a just world plays a significant role in the unemployed person’s coping process.     

Acidic and neutral drugs screen in blood with quantitation using microbore high-performance liquid chromatography–diode array detection and capillary gas chromatography–flame ionization detection

Blood previously acidified with aqueous saturated ammonium chloride solution was extracted with ethyl acetate. The dried extract was subjected to acetonitrile–hexane partition. The acetonitrile portion was analysed for the presence of acidic and neutral drugs by HPLC–DAD (200 mm×2.1 mm I.D. microbore ODS-Hypersil column) and GC–FID (25 m narrow-bore×0.25 mm I.D. HP-5 column with 0.33 μm film thickness). The protocol was found to be suitable for both clinical toxicology (including emergency toxicology) and postmortem toxicology. At least 66 drugs of interest were unequivocally identified by RRTs (HPLC) and UV spectra (DAD) match while another 12 were unequivocally identified by double RRTs match (HPLC and GC). Quantitation was facilitated by incorporating calibration blood standards in each assay batch. The five drugs most commonly encountered in clinical blood specimens (1150 cases) were: paracetamol (47.4% of the cases); chlormezanone (6.6%), theophylline (1.74%), naproxen (1.65%) and mefenamic acid (1.56%). The following drugs were detected in toxicologically significant quantities in postmortem blood specimens (245 cases): phenobarbitone (1.22% of the cases), naproxen (0.82%), chlormezanone (0.82%), theophylline (0.82%), carbamazepine (0.41%) and paracetamol (0.41%).     

民间组织对我国社会政治稳定的影响

民间组织在我国改革开放以后迅猛发展,对我国社会政治稳定既有积极影响的一面,也有一定的负面影响。加强对民间组织的管理,保证民间组织健康有序地发展不仅仅是登记管理机关的重要任务。公安机关作为维护社会稳定的职能部门,也应该从巩固国家政权和维护社会政治稳定的高度,积极会同登记管理机关,促使民间组织积极作用的发挥,尽可能地缩小和克服其消极面的影响,为改革开放和现代化建设创造一个稳定的社会环境。