Understanding Variations of Soil Mapping Units and Associated Data for Forensic Science

Soil samples have potential to be useful in forensic investigations, but their utility may be limited due to the inherent variability of soil properties, the wide array of analytical methods, and complexity of data analysis. This study examined the differentiation of similar soils based on both gross (texture, color, mineralogy) and explicit soil properties (elemental composition, cation exchange, Fe‐oxyhydroxides). Soils were collected from Fallbrook and adjacent map units from Riverside and San Diego Counties in California. Samples were characterized using multiple techniques, including chemical extracts, X‐ray diffraction (XRD), and Fourier transform infrared spectroscopy. Results were analyzed using multiple analytical approaches to compare counties and land uses. Some analyses (XRD, extractions) were better at distinguishing among samples than others (color, texture). Ratios of rare earth elements were particularly useful for distinguishing samples between counties. This potential to “fingerprint” soils illustrates the usefulness of a comprehensive soil database for criminal investigators.     

Orphan drug incentives in the pharmacogenomic context: policy responses in the US and Canada

Advances in pharmacogenomic research and increasing industry interest in personalized medicine have important implications for the way that orphan drug policies are interpreted and applied. Concerns have been raised about the potential impact of pharmacogenomics and new genomic technologies on our understanding of how disease categories are delineated, and subsequently, how the concept of rare disease should be defined for the purposes of orphan drug policies. This article considers whether orphan drug legislation can be drafted in a way that will maximize benefits and minimize concerns relating to the impact of pharmacogenomics on orphan drug research and development. After reviewing the issues that may arise at the intersection of orphan drug policies and pharmacogenomics, this article will discuss the potential impact of pharmacogenomics at two critical points: orphan designation and approval of the drug product. At each of these points, the relevant aspects of current US orphan drug legislation are examined, focusing on the extent to which recent amendments may address concerns that have been raised previously. This analysis will then provide the foundation for a critical review and recommendations regarding the proposed new Canadian orphan drug framework.     

Death from Barotrauma Due to Compressed Air: A Medico‐legal Analysis

Lesions of the digestive tract due to barotrauma resulting from compressed air application are not common, are rarely lethal, and largely affect the sigmoid and descending colon. Moreover, their pathogenic mechanism is a topic of discussion because these lesions have multiple characteristics. Here, the authors describe an autoptic case of death from lesions of the ascending and transverse segments, with perforations and bleeding suffusions as well as ischemic areas covered the colonic wall that was extremely thinned, congested, and hemorrhagic, with considerable flattening leading to disappearance of the mucosal folds and with numerous petechial hemorrhages. The pathological framework of lung congestion made it possible to identify the mechanism responsible for this death as depletion of the heart's pumping function, which contributed significantly to the acute respiratory failure due to respiratory distress as well as to reduced mobility of the diaphragm due to intestinal distension. Acute heart failure played an important role in this death.     

The Race for Critical Minerals in an Era of Geopolitical Realignments

ABSTRACT

The decarbonisation of the global economy in response to the climate crisis and the fourth industrial revolution, featuring artificial intelligence (AI) and 5G networks (massively accelerated in response to the coronavirus pandemic), has triggered a race to secure uninterrupted access to critical raw minerals (CRMs) that are indispensable inputs for high-technology applications. Moreover, China’s Belt and Road Initiative, which unites Eurasia and Africa and loops in South America into a seamless space of trade, infrastructure and digital connectivity, challenges the dominance of traditional industrial powers (the United States, the European Union and Japan) and requires critical minerals. Rare earths, lithium and cobalt – among the most critical of the CRMs – are found in high geographic concentration, creating hotspots of contention, especially in unstable parts of the world. As economic transformations accelerate, securing access to these materials will both impact and help shape geopolitics in the years to come.     

中日在稀有金属领域的战略博弈——兼评中国稀土产业政策效果

日本本土稀有金属资源极度匮乏,但却是世界稀有金属消费大国和应用强国。随着稀有金属在战略性新兴产业应用日益广泛,中日两个稀有金属资源和应用大国在该领域展开了数轮博弈。为应对中国收紧稀有金属出口的一揽子政策措施,日本综合运用技术、经济、政治、外交手段,形成了以技术创新为核心、市场化为基本导向、官产学联动的稀有金属保障战略体系,有效缓解了其国内稀有金属供给趋紧的压力,进一步巩固了日本在稀有金属全球价值链上的竞争优势。长期以来,中国稀有金属的资源优势未能上升为产业优势。借鉴日本稀有金属保障体系,应加快构建稀有矿产资源国家战略,推动稀有金属产业链向高端环节延展,切实维护国家资源安全。     

大熊猫等八种野生珍稀动物蛔虫ITS-2基因的序列分析

为了探讨寄生在大熊猫、小熊猫、黑猩猩、白眉长臂猿和4种熊科动物(北极熊、棕熊西藏亚种、狗熊四川亚种和棕熊东北亚种)体内蛔虫的分类地位,测定了核糖体第二内转录间隔区(ITS-2)基因序列,并对这些序列进行同源性分析和采用UPGMA法构建分子系统树。结果表明:寄生在大熊猫、小熊猫和4种熊科动物体内的蛔虫均为贝蛔属蛔虫;寄生在黑猩猩和白眉长臂猿体内的蛔虫为蛔属蛔虫。分析结果提示蛔虫与宿主之间存在协同进化关系。     

Self-Control,Violent Offending,and Homicide Victimization: Assessing the General Theory of Crime

Criminologists have long recognized that offending and victimization share common ground. Using Gottfredson and Hirschis general theory of crime, with its emphasis on self-control as a theoretical backdrop, we examine the extent to which self-control is related to both violent offending and homicide victimization. To examine this issue, we use 5-year post-parole data on violent offending and homicide victimization from a sample of parolees from the California Youth Authority. Using rare-events logistic regression models, results indicate that self-control is related to each outcome, but that other risk factors are also uniquely related to each outcome. The implications of this study for theory and future research are addressed.To whom correspondence should be addressed: Department of Criminology, Law and Society, University of Florida, P.O. Box 115950, 201 Walker Hall, Gainesville, FL 32611-5950; Phone: +1-352-392-1025, ext. 213; E-mail: apiquero@ufl.edu     

Voltammetric analysis of luminescent markers in gunshot residues

Currently, SEM-EDS is used to detect gunshot residue (GSR) from the presence of Ba, Pb, and Sb in the sample. However, the development of new nontoxic ammunition (NTA) has prevented conventional metals from being found. In this work, we aim to determine the presence of an inorganic luminescent chemical marker based on rare earth in gunshot residues using the technique of squarewave voltammetry (SWV). After firing, the luminescent complex [(Eu₂Zr)(btc)₃(Hbtc)_0.5.6H₂O], which is used as a chemical marker, can be detected under a UV lamp. An aqueous solution with 0.1 mol L⁻¹ KCl as supporting electrolyte can be easily collected on carbon paste electrode surfaces for SWV analysis A = 100 mV, f = 10 Hz, and step potential of 5 mV are required. The luminescent marker incorporated into the carbon paste electrode showed two anodic peak currents in the region of 0.4 V (vs Ag/AgCl) and at 0.75 V (vs Ag/AgCl) and also a cathodic one in 0.4 V (vs Ag/AgCl). SEM-EDS was able to analyze the same voltammetric results for conventional and nontoxic ammunition containing the luminescent marker. Therefore, voltammetry and SEM-EDS are valid for detecting the new residue marker in GSR. Despite this, the electrochemical method is still more advantageous because of its low cost and lack of expensive equipment and supplies in forensic laboratories.