健脾补肾泄浊法治疗肾性贫血30例临床观察

目的:观察健脾补肾泄浊法配合促红细胞生成素(EPO)治疗肾性贫血的临床疗效。方法:治疗组给予EPO(宁红欣)3000u皮下注射,并口服健脾补肾泄浊中药;对照组只给予EPO3000u皮下注射。结果:治疗组总有效率为86.2%,对照组总有效率为70.0%。治疗组疗效优于对照组,差异有显著性(P<0.05)。两组治疗后血红蛋白、红细胞比容均较治疗前明显上升(P<0.01),但治疗组优于对照组(P<0.05);治疗组血清肌酐、尿素氮、血清总蛋白治疗后与治疗前相比,差异有显著性(P<0.05),两组间比较,差异亦有显著性(P<0.05)。结论:健脾补肾泄浊法配合EPO治疗肾性贫血,能明显改善患者贫血状况,对肾功能有较好的保护作用,提高患者生活质量。

Effects of the therapy of Strengthening the Spleen,Tonifying the Kidney and Eliminating Turbid Urine in Treating Renal Anemia

Objective:To observe the curative effect of the therapy of strengthening the spleen,tonifying the kidney and eliminating turbid urine combined with erythropoietin(EPO) in treating renal anemia.Method:the treatment group was treated with the traditional Chinese medicine of strengthening the spleen ,tonifying the kidney and eliminating turbid urine and EPO hypodermic injection,while the control group was treated with EPO hypodermic injection.Result:The total effective rate of the treatment group was 86.2%,which was better than that(70.0% )of the control group(P<0.05).After the treatment, hemoglobin and hematocrit remarkablely increased in the two groups(P<0.01),but the treatment group was better than the control group (P<0.05).In treatment group,Serum creatinine,blood urea nitrogen and total protein were significamt different before and after the treatment(P<(0.05)),which were significamt different between the two groups after the treatment (P<0.05).Conclusion: The therapy of strengthening the spleen,tonifying the kidney and eliminating turbid urine combined with EPO can significantly improve the patientsanemia condition,protect renal function and improve the patientslife quality.