| 电针对慢性应激抑郁模型大鼠脑肠肽类激素的影响 |
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| 引用本文： | 秦丽娜 史榕荇 图娅. 电针对慢性应激抑郁模型大鼠脑肠肽类激素的影响[J]. 安徽中医药大学学报, 2007, 0(1): 25-26 |
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| 作者姓名： | 秦丽娜 史榕荇 图娅 |
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| 作者单位： | 北京中医药大学 北京100029 |
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| 基金项目： | 国家自然科学基金项目（30472181） |
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| 摘 要： | 目的:探讨电针“百会”、“印堂”、“天枢”穴改善抑郁症消化功能障碍的机制。方法:将30只SD雄性大鼠随机分为正常组、模型组、电针组,每组10只。用放射免疫法测定脑肠肽类激素下丘脑生长抑素(SS)和血清胃泌素(GAS)的含量。结果:慢性应激抑郁型模型大鼠下丘脑SS显著下降和血清GAS显著升高(P<0.01);电针可以升高下丘脑SS和降低血清GAS含量(P<0.05,P<0.01)。结论:调节脑肠肽类激素的释放,可能是电针改善抑郁状态下大鼠消化功能的作用途径之一。
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| 关 键 词： | 抑郁症 电针 消化功能障碍 脑肠肽 |
| 修稿时间： | 2006-10-12 |
The Effect of Electroacupuncture on Brain-gut Peptides in Rats with Chronic Stress Induced Depression |
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| QIN Li-n,SHI Rong-xing,TU Ya. The Effect of Electroacupuncture on Brain-gut Peptides in Rats with Chronic Stress Induced Depression[J]. Journal of Anhui Traditional Chinese Medical College, 2007, 0(1): 25-26 |
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| Authors: | QIN Li-n SHI Rong-xing TU Ya |
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| Affiliation: | Beijing University of Traditional Chinese Medicine, Beijing 100029, China |
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| Abstract: | Objective : To explore the treating mechanism of the functional dyspepsia caused by depression with electro-acupuncture at Baihui,Yintang,Tianshu points.Methods: Thirty male sprague dawley rats were randomly allocated to three groups follows: control group,model group and electroacupuncture group.To measure hypothalamus somatostatin(SS) and serum gastrin(GAS) with radioimmunoassay(RIA).Results: In rats with depression induced by chronic stress,the SS was lower(P<0.01) and the GAS was higher than that in control group(P<0.01).After electro-acupuncture,the SS was raised significantly(P<0.05) and the GAS was lowered(P<0.01).Conclusion: Electroacupuncture modulate the secretion of brain-gut peptides,it improves the functional dyspepsia caused by depression. |
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| Keywords: | Depression Electroacupuncture Functional dyspepsia Brain-gut peptides |
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