| 慢性支气管炎肺气虚证大鼠血清IL-8、MDA、SOD变化特征 |
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| 引用本文： | 赵蜀军,蔡圣荣,方志斌,刘涌,王元勋. 慢性支气管炎肺气虚证大鼠血清IL-8、MDA、SOD变化特征[J]. 安徽中医药大学学报, 2005, 0(2): 21-23 |
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| 作者姓名： | 赵蜀军 蔡圣荣 方志斌 刘涌 王元勋 |
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| 作者单位： | 安徽中医学院中西医结合临床学院 安徽合肥230038(赵蜀军，蔡圣荣，方志斌，刘涌)，安徽中医学院中西医结合临床学院 安徽合肥230038(王元勋) |
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| 基金项目： | 安徽省自然科学基金;00044118; |
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| 摘 要： | 目的:通过对肺气虚证大鼠血清白介素 8 (IL 8 )、丙二醛 (MDA)和超氧化物歧化酶(SOD)变化的实验研究,为肺气虚证客观定量化诊断和深入研究肺气虚证的本质提供依据。方法:将 60只大鼠随机分为对照组与模型组。复制肺气虚证模型,分别检测动脉血中IL 8、MDA和SOD水平。结果:模型组IL 8、MDA升高, SOD下降, (P<0. 05或P<0. 01),与对照组比较,差异有显著性。结论:肺气虚证大鼠血浆中IL 8、MDA和SOD含量的变化可作为肺气虚证重要的客观指标之一。
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| 关 键 词： | 肺气虚证 白介素-8 丙二醛 超氧化物歧化酶 |
| 修稿时间： | 2005-01-21 |
Changes and Meanings of IL-8, MDA, and SOD in Rats with Pulmonary Qi deficiency of Chronic Bronchitis |
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| ZHAO Shu-jun,CAI Sheng-rong,FANG Zhi-bin,Liu Yong,WANG Yuan-xun. Changes and Meanings of IL-8, MDA, and SOD in Rats with Pulmonary Qi deficiency of Chronic Bronchitis[J]. Journal of Anhui Traditional Chinese Medical College, 2005, 0(2): 21-23 |
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| Authors: | ZHAO Shu-jun CAI Sheng-rong FANG Zhi-bin Liu Yong WANG Yuan-xun |
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| Abstract: | Objective: To study the changs of interleukin-8(IL-8),malondial dehyde(MDA), and muperoxides dismutase(SOD) in rats, furthermore provide the evidence for essence and diagnose standard of pulmonary Qi deficiency syndrome. Method: Sixty rats were randomly divided into control group and model group. The pulmonary Qi deficiency rat models were set up. the changes of IL-8,MDA and SOD were analyzed.Result: In model group , the levels of IL-8 and MDA increased significantly in comparison with those of control group while the level of SOD decreased significantly (P<0.05 or P<0.01).Conclusion : It is one of the important factors of pulmonary Qi deficiency aggravating gradually that IL-8, MDA, and SOD variety were distantly significant. |
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| Keywords: | PuLmonary Qi deficiency Interleukin-8 Malondial dehyde Superoxides dismutase |
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