| 冠心病猝死心肌肌红蛋白缺失的免疫组化研究 |
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| 引用本文： | 陈新山,胡俊,秦启生,黄光照.冠心病猝死心肌肌红蛋白缺失的免疫组化研究[J].中国法医学杂志,1993(1). |
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| 作者姓名： | 陈新山 胡俊 秦启生 黄光照 |
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| 作者单位： | 同济医科大学法医病理学教研室 武汉430030 |
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| 摘 要： | 作者应用免疫组化ABC法首次对SCD及对照组病例的心肌Mb缺失情况进行了研究,并经扫描显微镜光度计测量及电子计算机统计分析,结果发现SCD组心肌Mb均有明显缺失,呈现多发、散在、节段性分布,而对照组无缺失,认为这种多发、散在、节段性Mb缺失可作为无大片心肌梗死的SCD病例的诊断标志之一,为SCD的尸检诊断开辟了新途径。
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| 关 键 词： | 冠心病猝死 肌红蛋白缺失 免疫组织化学 ABC法 |
IMMUNOHISTOCHEMICAL STUDY OF MYOGLOBIN DEPLETION FROM MYOCARDIUM IN THE CASES OF SUDDEN CORONARY DEATH |
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| Chen Xinshan Hu Jun Qin Qinsheng Huang Guangzhao.IMMUNOHISTOCHEMICAL STUDY OF MYOGLOBIN DEPLETION FROM MYOCARDIUM IN THE CASES OF SUDDEN CORONARY DEATH[J].Chinese Journal of Forensic Medicine,1993(1). |
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| Authors: | Chen Xinshan Hu Jun Qin Qinsheng Huang Guangzhao |
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| Institution: | Chen Xinshan Hu Jun Qin Qinsheng Huang Guangzhao Department of Forensic Pathology,Tongji Medical University,Wuhan 430030 |
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| Abstract: | Myoglobin (Mb)depletion from myocardium in the cases of sudden soronary death (SCD) and was firstly studied by an immunhistochemial technique (ABC method) in China. Mb was detected quantitatively using scanning microscope photmeter and the results were analyzed statistically by computer The results showed that there were marked depletion of Mb from myocardium in each case of SCD The Mb depleted arce were multiple, disseminatly and segmentally distributed while no depletion of Mb from myocardium in the cases of control group was seen We suggested that the depletion of Mb can be used as one of the diagnostic criterion in the cases of SCD. |
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| Keywords: | Sudden coronary death Myoglobin depletion Immunohistochemistry method |
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