| 挤压综合征大鼠血清酶浓度变化的初步研究 |
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| 引用本文： | Liu SP,Chen YC,Guo W,Cheng JD. 挤压综合征大鼠血清酶浓度变化的初步研究[J]. 法医学杂志, 2001, 17(4): 205-206 |
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| 作者姓名： | Liu SP Chen YC Guo W Cheng JD |
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| 作者单位： | 中山医科大学法医病理教研室, |
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| 摘 要： | 目的观察挤压伤大鼠血清肌酸激酶(CK)、肌酸激酶心肌同功酶(CK-MB)浓度的变化,阐明肢体挤压伤大鼠早期是否存在心脏损伤。方法复制挤压伤大鼠动物模型,全自动生化分析仪检测血清CK、CK-MB浓度的变化。结果挤压伤后12h,血清CK、CK-MB浓度显著升高,并持续48h以上。结论肢体挤压伤早期可能有心脏损伤的存在。
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| 关 键 词： | 挤压综合征 肌酸激酶 肌酸激酶心肌同功酶 |
| 文章编号： | 1004-5619(2001)04-0205-02 |
| 修稿时间： | 2000-12-12 |
The preliminary study on change of serum enzyme level in crush syndrome rat |
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| Liu S P,Chen Y C,Guo W,Cheng J D. The preliminary study on change of serum enzyme level in crush syndrome rat[J]. Journal of Forensic Medicine, 2001, 17(4): 205-206 |
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| Authors: | Liu S P Chen Y C Guo W Cheng J D |
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| Affiliation: | Department of Forensic Pathology, Sun Yat-Sen University of Medical Sciences, Guangzhou 510080. |
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| Abstract: | Objective To study the changes of serum creatinine kinase(CK) and its cardiac-specific isoenzyme compound(CK-MB) levels in crush injury rats.Methods Crush injury was produced in SD rats,the serum levels of CK and CK-MB were studied by automated biochemical analyzer.Results The levels of plasma CK and CK-MB were much higher in crush injury rats than those of the control group.Conclusions Cardiomyocyte injury may be induced in the early stage of crush injury rats. |
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| Keywords: | crush syndrome creatinine kinase creatinine kinase cardiac-specific isoenzyme compound |
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