The use of absorbance ratios in high-performance liquid chromatography for the identification of drugs of abuse |
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Institution: | 1. College of Information Engineering, Xuchang University, Xuchang, Henan, China;2. Xuchang Key Laboratory of Virtual Reality Technology, Xuchang, Henan, China;1. School of Environment, Nanjing Normal University, Nanjing, Jiangsu 210023, People’s Republic of China;2. Jiangsu Engineering Lab of Water and Soil Eco-remediation, Nanjing Normal University, Nanjing, Jiangsu 210023, People’s Republic of China;1. Nikolaev Institute of Inorganic Chemistry, Siberian Branch of the Russian Academy of Science, 630090 Novosibirsk, Russia;2. Federal Research Center, Boreskov Institute of Catalysis, 630090 Novosibirsk, Russia;1. Chair of Analytical Chemistry, Faculty of Chemistry, Warsaw University of Technology, Noakowskiego St. 3, 00-664, Warsaw, Poland;2. Saratov State Agrarian University, Teatralnaya Sq. 1, 410012, Saratov, Russian Federation;3. Institute of Inorganic Chemistry, University of Vienna, Waehringer Str. 42, A-1090, Vienna, Austria;4. Vernadsky Institute of Geochemistry and Analytical Chemistry, Kosygin St. 19, 119991, Moscow, Russian Federation;1. Department of Chemical and Biochemical Engineering, Technical University of Denmark, Søltofts Plads, Building 229, 2800 Lyngby, Denmark;2. Department of Food Science, University of Copenhagen, Rolighedsvej 26, DK-1958 Frederiksberg C, Denmark;3. Department of Nutrition, Exercise and Sports, University of Copenhagen, Rolighedsvej 26, DK-1958 Frederiksberg C, Denmark |
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Abstract: | Absorbance ratios at selected wavelengths and retention times were determined for 28 common drugs of abuse. Based on the values of three ratios, the drugs were placed into five classes. Within each class the individual member could be identified readily by its characteristic absorbance ratio and retention time. It was concluded that absorbance ratios in conjunction with retention times greatly enhance the utility of HPLC for the rapid analysis of drugs of abuse. |
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