A database of mitochondrial DNA hypervariable regions I and II sequences of individuals from Slovakia |
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| Authors: | Ivan Lehocký , Marian Baldovi
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udeví t K da&#x i,Ene Metspalu |
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| Affiliation: | aDepartment of Forensic Biology and DNA Analyse, Institute of Forensic Science of Police Corps, 812 72 Bratislava, Slovak Republic;bDepartment of Molecular Biology, Comenius University, Faculty of Natural Sciences, Bratislava, Slovak Republic;cInstitute of Molecular Physiology and Genetics, Slovak Academy of Science, Bratislava, Slovak Republic;dInstitute of Molecular and Cell Biology, Tartu University, Tartu, Estonia |
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| Abstract: | In order to identify polymorphic positions and to determine their frequencies and the frequency of haplotypes in the human mitochondrial control region, two hypervariable regions (HV1 and HV2) of the mitochondrial DNA (mtDNA) of 374 unrelated individuals from Slovakia were amplified and sequenced. Sequence comparison led to the identification of 284 mitochondrial lineages as defined by 163 variable sites. Genetic diversity (GD) was estimated at 0.997 and the probability of two randomly selected individuals from population having identical mtDNA types (random match probability, RMP) for the both regions is 0.60%. |
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| Keywords: | Mitochondrial DNA Hypervariable regions Haplotypes Population frequency Forensic science Slovak Republic |
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