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Amphetamine derivative related deaths
Affiliation:1. Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA;2. Paul and Carole Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA;3. Department of Psychology, East Tennessee State University, Johnson City, TN, USA;1. Laboratorio di Istopatologia Forense e Microbiologia Medico Legale - Sezione di Medicina Legale e delle Assicurazioni - Dipartimento di Scienze Biomediche per la Salute – Università degli Studi di Milano, Via Luigi Mangiagalli, 37 – 20133 Milano, Italy;2. Fondazione IRCCS Cà Granda – Ospedale Maggiore Policlinico di Milano, Anatomopatologo dirigente medico UOC Anatimia Patologica, Milano Italy;1. Centre on Theoretical Problems in Physical and Chemical Pharmacology, Russian Academy of Sciences, Moscow, Russia;2. Timpharm LTD, Moscow, Russia
Abstract:Amphetamine its methylendioxy (methylendioxyamphetamine methylenedioxymethylamphetamine, methylenedioxyethylamphetamine) and methoxy derivatives (p-methoxyamphetamine and p-methoxymethylamphetamine) are widely abused in Spanish society. We present here the results of a systematic study of all cases of deaths brought to the attention of the Madrid department of the Instituto Nacional de Toxicologia from 1993 to 1995 in which some of these drugs have been found in the cadaveric blood. The cases were divided into three categories: amphetamine and derivatives, amphetamines and alcohol, amphetamines and other drugs. Data on age, sex, clinical symptoms, morphological findings, circumstances of death, when known, and concentration of amphetamine derivatives, alcohol and other drugs in blood are given for each group. The information provided here may prove to be useful for the forensic interpretation of deaths which are directly or indirectly related to abuse of amphetamine derivatives.
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