| 噬菌体在细菌性疾病诊断和治疗中的应用 |
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| 引用本文： | 苏胜兵,马红霞,徐凤宇. 噬菌体在细菌性疾病诊断和治疗中的应用[J]. 中国兽医科学, 2011, 0(5) |
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| 作者姓名： | 苏胜兵 马红霞 徐凤宇 |
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| 作者单位： | 吉林农业大学动物科技学院动物生产及产品质量安全教育部重点实验室; |
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| 基金项目： | 吉林省自然科学基金项目(201115191) |
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| 摘 要： | 从重组噬菌体法、生物扩增法、噬菌体触发的离子级联感应技术及耐药性检测4个方面阐述了噬菌体在病原菌检测中的作用;从细菌分型的角度阐述了噬菌体在病原菌分型中的应用;从活噬菌体、裂解酶、药物载体3个方面陈述了噬菌体在细菌性疾病治疗方法中的研究进展,并分析了噬菌体在应用中的优缺点,展望了今后的研究和应用前景。
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| 关 键 词： | 噬菌体 特异性 诊断 治疗 |
Review of application of bacteriophage in the diagnosis and therapy for bacteria infection |
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| SU Sheng-bing,MA Hong-xia,XU Feng-yu. Review of application of bacteriophage in the diagnosis and therapy for bacteria infection[J]. Chinese Veterinary Science, 2011, 0(5) |
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| Authors: | SU Sheng-bing MA Hong-xia XU Feng-yu |
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| Affiliation: | SU Sheng-bing,MA Hong-xia,XU Feng-yu(Key Laboratory of Animal Production,Product Quality and Security of the Ministry of Education/College of Animal Science and Technology,Jilin Agricultural University,Changchun 130118,China) |
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| Abstract: | This article reviews four kinds of detection technology for pathogen,including recombinant bacteriophage method,PhaB method,sensing of phage-triggered ion cascade technology,detection of the drug resistance.Meanwhile,the application of bacteriophage in typing bacteria was illustrated.Furthermore,the research advance in three means for treating bacterial diseases using bacteriophage was also summarized in this paper,including viable bacteriophage,lysin,drug carrier.The advantages and disadvantages of these t... |
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| Keywords: | bacteriophage specificity diagnosis therapy |
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