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An Unusual Cause of Headache and Sudden Death of a Young Sailor—Postmortem Computed Tomography and Histological Findings of a Fatal Retroperitoneal Malignant Mixed Germ Cell Tumor
Authors:Belinda Lee M.B.B.S.   F.R.C.Path.  Michelle Chan M.B.B.S.   F.R.C.Path.  Ronald Goh M.B.B.S.   F.R.C.P.A.
Affiliation:1. Forensic Medicine Division, Health Sciences Authority, Singapore, Singapore;2. Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore
Abstract:A 26‐year‐old Caucasian sailor, with no past medical history aside from headache for the last 1 week, was found dead in his cabin. The body was stored in a refrigerator on board and disembarked for autopsy 3 days later. Autopsy showed a large, nodular, necrotic and hemorrhagic retroperitoneal mass, and smaller hemorrhagic nodules in the brain, lungs, liver, and left kidney, with the brain being markedly edematous. Both testes were descended and normal. Histologically, the retroperitoneal mass showed a malignant mixed germ cell tumor comprising choriocarcinoma, embryonal carcinoma, and teratoma components. Retroperitoneal extragonadal germ cell tumors are uncommon, and this case of a young male who presented with headache and sudden death due to metastases is extremely rare.
Keywords:forensic science  headache  sudden death  retroperitoneal  extragonal  germ cell tumor
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