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实验性心脏挫伤动物模型的建立
引用本文:官大威,徐建青,李德祥,李庆生,金鑫,王怀良,贾静涛.实验性心脏挫伤动物模型的建立[J].中国法医学杂志,1995(2).
作者姓名:官大威  徐建青  李德祥  李庆生  金鑫  王怀良  贾静涛
作者单位:中国医科大学法医学系法医病理学教研室!沈阳,110001,中国医科大学法医学系法医病理学教研室!沈阳,110001,中国医科大学法医学系法医病理学教研室!沈阳,110001,中国医科大学法医学系刑事技术照像室!沈阳,110001,中国医科大学基础医学院药理学教研室!沈阳,110001,中国医科大学基
摘    要:本研究应用自制机械式弹性拉力打击器以9.1~10.5m/s速度冲击动物胸骨心前区,不仅导致左右心室压力、心电图及心率发生改变,而且造成了心脏挫伤等宏观的病理形态学变化,成功地建立了心脏挫伤动物模型,为深入研究钝力性心脏外伤奠定了基础。

关 键 词:心脏挫伤  实验性动物模型

THE ESTABLISHMENT OF EXPERIMENTAL ANIMAL MODEL OF CARDIAC CONTUSION
Guan Dawei, et al.THE ESTABLISHMENT OF EXPERIMENTAL ANIMAL MODEL OF CARDIAC CONTUSION[J].Chinese Journal of Forensic Medicine,1995(2).
Authors:Guan Dawei  
Abstract:In the present study an experimental animal model of closed chest cardiac contusion in dogs was successfully established by impacting precardial area at the velocity of 9- 1 - 10. 5m/s with home-made elastic cord propelled impactor, After impact, some significant abnormalities of the left and right ventricular pressure,ECG and heart rate were recorded. Cardiac contusions were demonstrated at au-topsy. The establishment of the experimental cardiac contusion model could provide the tool for further study on nonpenetrating cardiac injury.
Keywords:Cardiac contusion  Experimental animal model  
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