Detection of methamphetamine and amphetamine in a skeletonized body buried for 5 years |
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| Authors: | T Kojima I Okamoto T Miyazaki F Chikasue M Yashiki K Nakamura |
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| Affiliation: | 1. Ningxia Medical University, Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education/Key Laboratory of Reproduction and Genetics/Department of Medical Genetics and Cell Biology, Yinchuan 750004, PR China;2. Clinical Medicine Science, Peking University Health Science Center, Beijing 100191, PR China;3. Surgical Oncology of General Hospital of Ningxia Medical University, Yinchuan 750004, PR China.;1. Department of Anatomy & Cell Biology, School of Medicine, Wayne State University, Detroit, MI 48201, USA;2. College of Nursing, Wayne State University, Detroit, MI 48202, USA;3. Department of Pharmacology, School of Medicine, Wayne State University, Detroit, MI 48201, USA;4. Center for Integrative Metabolic and Endocrine Research, Department of Psychiatry & Behavioral Neurosciences, School of Medicine, Wayne State University, Detroit, MI 48201, USA |
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| Abstract: | A 28-year-old male methamphetamine abuser, who had been buried for 5 years after being killed by strangulation, was found skeletonized. Methamphetamine and amphetamine in the significantly denatured fatty material of the bone marrow were analyzed by gas chromatography and gas chromatography-mass spectrometry. The confirmation of the chemicals was carried out by chemical ionization (CI) mass chromatography, CI mass spectrometry and CI mass fragmentography. The concentrations of methamphetamine and amphetamine determined by CI mass fragmentography were 1.0 mumol/100 g and 0.1 mumol/100 g, respectively. The method used would seem to be very useful for determination of methamphetamine and amphetamine in marked putrefied biological materials. |
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