| PAP免疫组织化学技术检测血小板膜糖蛋白 |
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| 引用本文： | 顾晓生,薛义旗,祝家镇. PAP免疫组织化学技术检测血小板膜糖蛋白[J]. 中国法医学杂志, 1991, 0(3) |
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| 作者姓名： | 顾晓生 薛义旗 祝家镇 |
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| 作者单位： | 南京医学院法医学教研室 210005(顾晓生，薛义旗)，中山医科大学法医学系 广州(祝家镇) |
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| 摘 要： | <正> 血小板膜糖蛋白 GPⅠ_b 和 GPⅢa 在血小板粘附、聚集中起着极其重要的作用。为了直接检测组织中血小板粘附、聚集和血栓形成,我们建立了应用抗人血小板膜糖蛋白 GPⅠ_b和 GPⅢa 的单克隆抗体的 PAP 免疫组织化学技术,并首次对该技术在法医学中的应用进行了初步探讨。
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DETECTION OF PLATELET MEMBRANE GLYCOPROTEIN WITH PAP-IMMUNOHISTOCHEMICAL TECHNIQUE |
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| Gu Xiaosheng Xue Yiqi. DETECTION OF PLATELET MEMBRANE GLYCOPROTEIN WITH PAP-IMMUNOHISTOCHEMICAL TECHNIQUE[J]. Chinese Journal of Forensic Medicine, 1991, 0(3) |
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| Authors: | Gu Xiaosheng Xue Yiqi |
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| Affiliation: | Gu Xiaosheng Xue Yiqi Department of Forensic Medicine,Nanjing Medical College,210005Zhu Jia Zhen Faculty of Forensic Medicine,Sun Yat-Sen University of Medical Sciences Guangzhou 510089 |
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| Abstract: | The platelets in the human mixed thrombus,hyaline thrombus antemortemand postmrtem skin incision wounds were detected by the PAP-immunohisto-chemical technique using monoclonal antibodies against the human platelet mem-brane glycoprotein(GPIb,GPIIIa).The positive reaction were observed inthe mixed thrombus,hyaline thrombus and in all the antrmortem skin incisionwounds,but not in the postmortem skin wounds.The significance of theapplication of this technique in the forensic medicine practice was discussed. |
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| Keywords: | Platelet membrane glycoprotein Immunohistochemical technique Thrombus Skin incision wound |
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