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| MiniSTR技术的研究进展 | |
| 引用本文： | Wang HP,Liu C,Sun HY. MiniSTR技术的研究进展[J]. 法医学杂志, 2006, 22(2): 159-160,I0001,I0002 |
| 作者姓名： | Wang HP Liu C Sun HY |
| 作者单位： | 1. 中山大学基础医学院法医学系,广东,广州,510080;广州市刑事科学技术研究所,广东,广州,510030 2. 广州市刑事科学技术研究所,广东,广州,510030 3. 中山大学基础医学院法医学系,广东,广州,510080 |
| 摘 要： | 短串联重复序列(STR)是法医DNA鉴定中最常用和最重要的遗传标记,但是对于降解和微量的DNA样品,经常得不到完整的DNA分型甚至分型失败。MiniSTR技术通过设计更靠近重复序列的引物,得到更短一些的STR基因座,提高了降解和微量检材的DNA分型成功率。本文综述了miniSTR技术的研究进展,以服务于法医学实践。 |
| 关 键 词： | MiniSTR 降解DNA 法医DNA分型 |
| 文章编号： | 1004-5619(2006)02-0159-04 |
| 修稿时间： | 2005-09-14 |
Recent advancement in miniSTR research |
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| Wang Hui-Pin,Liu Chao,Sun Hong-Yu. Recent advancement in miniSTR research[J]. Journal of Forensic Medicine, 2006, 22(2): 159-160,I0001,I0002 | |
| Authors: | Wang Hui-Pin Liu Chao Sun Hong-Yu |
| Affiliation: | Department of Forensic Biology, Sun Yat-sen University, Guangzhou 510080, China. |
| Abstract: | As the most popular and important inherited marker used in forensic identification, short tandem repeat (STR) always have partial DNA profiling or even no results when handling degraded or minute DNA sample. Through redesigning primers close to STR core repeats, MiniSTR can access shorter STR loci and increase success rate of DNA profiling in degraded or minute DNA sample. The review provides an update on the advancement of miniSTR research to give information in the practice of forensic science. |
| Keywords: | miniSTR degraded DNA forensic DNA profiling |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |