| 狂犬病病毒反向遗传学的研究进展 |
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| 引用本文： | 焦文强,殷相平,柳纪省. 狂犬病病毒反向遗传学的研究进展[J]. 中国兽医科学, 2011, 0(9) |
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| 作者姓名： | 焦文强 殷相平 柳纪省 |
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| 作者单位： | 中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室农业部草食动物疫病重点开放实验室; |
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| 基金项目： | 国家高技术研究发展计划(863)项目(2006AA10A204) |
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| 摘 要： | 对狂犬病病毒反向遗传学操作系统进行了综述,论述了狂犬病病毒反向遗传操作技术的发展状况,并对反向遗传学操作技术在狂犬病病毒致病机理、狂犬病疫苗以及病毒载体研究中的应用进行了综述,对各种病毒拯救方法进行了比较,并对狂犬病病毒反向遗传学操作技术的应用进行了初步探讨。
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| 关 键 词： | 狂犬病病毒 反向遗传学 应用 |
Research advances in reverse genetics of rabies virus |
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| JIAO Wen-qiang,YIN Xiang-ping,LIU Ji-xing. Research advances in reverse genetics of rabies virus[J]. Chinese Veterinary Science, 2011, 0(9) |
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| Authors: | JIAO Wen-qiang YIN Xiang-ping LIU Ji-xing |
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| Affiliation: | JIAO Wen-qiang,YIN Xiang-ping,LIU Ji-xing(State Key Laboratory of Veterinary Etiological Biology/Key Laboratory of Grazing Animal Diseases of the Ministry of Agriculture/Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou 730046,China) |
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| Abstract: | Reverse genetics for rabies virus was reviewed in the present article,including the development history of reverse genetics,application in pathogenesis,live attenuated vaccine and rabies virus vector.In addition,the advantages and disadvantages of each method rescuing rabies virus were discussed,and the application of reverse genetics for rabies virus was summarized. |
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| Keywords: | rabies virus reverse genetics application |
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