Diversity of 17-locus Y-STR haplotypes in Upper (Southern) Egyptians |
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| Authors: | Ghada A Omran Guy N Rutty |
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| Institution: | a East Midlands Forensic Pathology Unit, University of Leicester, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK
b Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH, UK |
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| Abstract: | Seventeen Y-STR loci included in the AmpF?STR® Yfiler™ PCR Amplification kit were typed in a population sample of 208 males from Upper (South) Egypt. Of 204 observed haplotypes, 200 were unique (96.6%) and 4 were found twice each. The 17 loci gave a discriminating power of 0.9998. DYS458 showed the highest diversity as a single-locus marker (h = 0.868) along with a high frequency of microvariants and new alleles (22% of the sample). Other loci revealed duplicated and null alleles. Comparative analysis with Y-STR datasets of relevant populations and submission of the haplotypes to the Y-STR Haplotype Reference Database (YHRD) were undertaken. |
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| Keywords: | Forensic Y-STR Upper Egyptians South Egypt |
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