Automatic data processing of reference DNA-profiles from FTA and non-FTA samples

The new Swedish DNA legislation resulted in a huge increase in reference samples. In 2006 approximately 25,000 reference samples were received compared to 5000 in 2005. To meet this increase the reference samples had to be handled in a more automatic process than previously. A new module in the LIMS system automatically compares duplicate results and creates confirmed results if the DNA profiles meet the set requirements. Profiles without automatically confirmed results need to be manually investigated. Certain rules and settings in the LIMS sort these samples. Evaluators are able to combine the results to form confirmed results or chose to reanalyse the samples. At a rough estimate, 80% of all FTA samples are automatically assigned confirmed results, without any manual handling. Only 0.09% of the reference samples was terminated without results in every marker.